Molecular biological and biochemical characterization of the human type 2 selenodeiodinase

Endocrinology

Volumn 137, Issue 8, 1996, Pages 3308-3315

  Salvatore, Domenico ^a   Bartha, Tibor ^a   Harney, John W ^a   Larsen, P Reed ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; IODIDE PEROXIDASE; SELENIUM; THYROID HORMONE;

ARTICLE; CODON; DNA LIBRARY; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; ENZYME ANALYSIS; HORMONE ACTION; HUMAN; HUMAN TISSUE; IODINATION; MOLECULAR BIOLOGY; OPEN READING FRAME; PRIORITY JOURNAL; RNA TRANSCRIPTION; SKELETAL MUSCLE;

EID: 0029938790     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.8.8754756     Document Type: Article

References (40)

1. Berry MJ, Banu L, Larsen PR 1991 Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature 349:438-440
2. Mandel SJ, Berry MJ, Kieffer JD, Harney JW, Warne RL, Larsen PR 1992 Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase. J Clin Endocrinol Metab 75:1133-1139
3. Toyoda N, Harney JW, Berry MJ, Larsen PR 1994 Identification of critical amino acids for 3,5′,3′-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes. J Biol Chem 269:20329-20334
4. Maia AL, Berry MJ, Sabbag R, Harney JW, Larsen PR 1995 Structural and functional differences in the Diol gene in mice with inherited type 1 deiodinase deficiency. Mol Endocrinol 9:969-980
5. Leonard JL, Visser TJ 1986 Biochemistry of deiodination. In: Hennemann G (ed) Thyroid Hormone Metabolism. Marcel Dekker, New York, pp 189-229
6. Berry MJ, Kieffer JD, Harney JW, Larsen PR 1991 Selenocysteine confers the biochemical properties of the type I iodothyronine deiodinase. J Biol Chem 266:14155-14158
7. Berry MJ, Kieffer JD, Larsen PR 1991 Evidence that cysteine, not selenocysteine, is in the catalytic site of type II iodothyronine deiodinase. Endocrinology 129:550-552
8. Silva JE, Larsen PR 1977 Pituitary nuclear 3,5-3′-triiodothyronine and thyrotropin secretion: an explanation for the effect of thyroxine. Science 198:617
9. Visser TJ, Leonard JL, Kaplan MM, Larsen PR 1982 Kinetic evidence suggesting two mechanisms for iodothyronine 5′-deiodination in rat cerebral cortex. Proc Natl Acad Sci USA 79:5080-5084
10. Visser TJ, Kaplan MM, Leonard JL, Larsen PR 1983 Evidence for two pathways of iodothyronine 5′-deiodination in rat pituitary that differ in kinetics, propylthyiouracil sensitivity, and response to hypothyroidism. J Clin Invest 71:992-1002
11. Leonard JD, Mellen SA, Larsen PR 1982 Thyroxine 5′-deiodinase activity in brown adipose tissue. Endocrinology 112:1153-1155
12. Kaplan MM, Shaw EA 1984 Type II iodothyronine 5′-deiodination by human and rat placenta in vitro. J Clin Endocrinol Metab 59:253-257
13. Kaplan MM, Pan C, Gordon PR, Lee JK, Gilchrest BA 1988 Human epidermal keratinocytes in culture convert thyroxine to 3,5,3′-triiodothyronine by type II iodothyronine deiodination: a novel endocrine function of the skin. J Clin Endocrinol Metab 66:815-822
14. Silva JE, Dick TE, Lasen PR 1978 Contribution of local tissue thyroxine monodeiodination to the nuclear 3,5,3′-triiodothyronine in pituitary, liver and kidney of euthyroid rats. Endocrinology 103:1196-1207
15. 3 as determined by in vivo techniques. Endocrinology 120:55-62
16. Crantz FR, Silva JE, Larsen PR 1982 Analysis of the sources and quantity of 3,5,3′-triiodothyronine specifically bound to nuclear receptors in rat cerebral cortex and cerebellum. Endocrinology 110:367-375
17. Davey JC, Becker KB, Schneider MJ, St.Germain DL, Galton VA 1995 Cloning of a cDNA for the type II iodothyronine deiodinase. J Biol Chem 270:26786-26789
18. Auffray C, Behar G, Bois F, Boucher C, daSilva C, Devignes MD, Duprat S, Houlgatte R, Jumeau MN, Lamy B, Lorenzo F, Mitchell H, Mariage-Samson R, Pietu G, Pouliot Y, Sebastiani-Kabaktchis C, Tessier A 1995 IMAGE: integrated molecular analysis of the human genome and its expression. C R Acad Sci [D] (Paris) 318:263-272
19. Aruffo A, Seed B 1987 Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc Natl Acad Sci USA 84:8573-8577
20. Salvatore D, Low SC, Berry MJ, Maia AL, Harney JW, Croteau W, St.Germain DL, Larsen PR 1995 Type 3 iodothyronine deiodinase: cloning, in vitro expression and functional analysis of the placental selenoenzyme. J Clin Invest 95:2421-2430
21. Berry MJ, Banu L, Chen Y, Mandel SJ, Kieffer JD, Harney JW, Larsen PR 1991 Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3′ untranslated region. Nature 353:273-276
22. Berry MJ, Banu L, Harney JW, Larsen PR 1993 Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons. EMBO J 12:3315-3322
23. Gossen M, Bujard H 1992 Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89:5547-5551
24. Brent GA, Larsen PR, Harney JW, Koenig RJ, Moore DD 1989 Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor. J Biol Chem 264:178-182
25. Berry MJ, Kates AL, Larsen PR 1990 Thyroid hormone regulates type I deiodinase messenger RNA in rat liver. Mol Endocrinol 4:743-748
26. Schoenmakers CHH, Pigmans IGAJ, Visser TJ 1992 Species differences in liver type I iodothyronine deiodinase. Biochim Biophys Acta 1121:160-166
27. Berry MJ, Harney JW, Ohama T, Hatfield DL 1994 selenocysteine insertion or termination: factors affecting UGA codon fate and complementary anticodon:codon mutations. Nucleic Acids Res 22:3753-3759
28. Chanoine JP, Safran M, Farwell AP, Tranter P, Ekenbarger DM, Dubord S, Alex S, Arthur JR, Beckett GJ, Braverman LE, Leonard JL 1992 Selenium deficiency and type II 5′-deiodinase regulation in the euthyroid and hypothyroid rat: evidence of a direct effect of thyroxine. Endocrinology 130:479-484
29. Toyoda N, Berry MJ, Harney JW, Larsen PR 1995 Topological analysis of the integral membrane protein, type 1 iodothyronine deiodinase (D1). J Biol Chem 270:12310-12318
30. McCaughan KK, Brown CM, Dalphin ME, Berry MJ, Tate WP 1995 Translational termination efficiency in mammals is influenced by the base following the stop codon. Proc Natl Acad Sci USA 92:5431-5435
31. Larsen PR, Silva JE, Kaplan MM 1981 Relationships between circulating and intracellular thyroid hormones: physiological and clinical implications. Endocr Rev 2:87-102
32. Houstek J, Vizek K, Pavelka S, Kopecky J, Krejcova E, HermanskaJ, Cermakova M 1993 Type II iodothyronine 5′-deiodinase and uncoupling protein in brown adipose tissue of human newborns. J Clin Endocrinol Metab 77:382-387
33. Gallon VA, Hiebert A 1988 The ontogeny of iodothyronine 5′-monodeiodinase activity in Rana catesbeiana tadpoles. Endocrinology 122:640-645
34. 3 formation in different skeletal muscle types of normal and hyperthyroid rats. Acta Endocrinol (Copenh) 88:306-320
35. LoPresti JS, Eigen A, Kaptein E, Anderson KP, Spencer CA, Nicoloff JT 1989 Alteration in 3,3′,5′-triiodothyronine metabolism in response to propylthiouracil, dexamethasone, and thyroxine administration in man. J Clin Invest 84:1650-1656
36. DiStefano JJ, Jang M, Malone TK, Broutman M 1982 Comprehensive kinetics of triiodothyronine production, distribution, and metabolism in blood and tissue pools of the rat using optimized blood-sampling protocols. Endocrinology 110:198-213
37. Silva JE, Larsen PR 1983 Adrenergic activation of triiodothyronine production in brown adipose tissue. Nature 305:712-713
38. Meinhold H, Campos-Barros A, Walzog B, Kohler R, Muller F, Behne D 1993 Effects of selenium and iodine deficiency on type I, type II and type III iodothyronine deiodinases and circulating thyroid hormones in the rat. Exp Clin Endocrinol 101:87-93
39. Chanoine JP, Safran M, Farwell AP, Dubord S, Alex S, Stone S, Arthur JR, Braverman LE, Leonard JL 1992 Effects of selenium deficiency on thyroid hormone economy in rats. Endocrinology 131:1787-1792
40. Safran M, Farwell AP, Leonard JL 1991 Evidence that type II 5′-deiodinase is not a selenoprotein. J Biol Chem 266:13477-13480