Chemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation

Journal of the American Chemical Society

Volumn 130, Issue 7, 2008, Pages 2195-2201

  Szekely, Joseph ^a   Rizzo, Carmelo J ^a   Marnett, Lawrence J ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXOPROPENYL ADDUCTS; PYRIMIDINE NUCLEOSIDES;

AMINO ACIDS; CHEMICAL PROPERTIES; CROSSLINKING; PH EFFECTS;

ORGANIC COMPOUNDS;

AMINO ACID; DOUBLE STRANDED DNA; LYSINE DERIVATIVE; MALONALDEHYDE; N 2 OXOPROPENYLDEOXYGUANOSINE; N ALPHA ACETYLLYSINE; PURINE NUCLEOSIDE DERIVATIVE; PYRIMIDINE NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG; CROSS LINKING REAGENT; DEOXYGUANOSINE; DRUG DERIVATIVE; LYSINE; N(ALPHA) ACETYLLYSINE; N(ALPHA)-ACETYLLYSINE; PURINE NUCLEOSIDE; PYRIMIDINE NUCLEOSIDE;

ACIDITY; ARTICLE; CHEMICAL STRUCTURE; CROSS LINKING; MOLECULAR STABILITY; PH; PKA; PROTEIN DNA INTERACTION; REACTION ANALYSIS; RING CLOSING METATHESIS; SYNTHESIS; TITRIMETRY; CHEMISTRY; DNA ADDUCT; KINETICS;

AMINO ACIDS; CROSS-LINKING REAGENTS; DEOXYGUANOSINE; DNA ADDUCTS; KINETICS; LYSINE; MALONDIALDEHYDE; PURINE NUCLEOSIDES; PYRIMIDINE NUCLEOSIDES;

EID: 39549122240     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja074506u     Document Type: Article

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