Influence of methylglyoxal on antioxidant enzymes and oxidative damage

Toxicology Letters

Volumn 93, Issue 2-3, 1997, Pages 141-152

  Choudhary, Dharamainder ^a   Chandra, Dhyan ^a   Kale, Raosaheb K ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

Antioxidant enzymes; GSH content; Lipid peroxidation; Methylglyoxal; Toxic effect

Indexed keywords

ANTIOXIDANT; CATALASE; ENZYME; FREE RADICAL; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HYDROXYACYLGLUTATHIONE HYDROLASE; LACTOYLGLUTATHIONE LYASE; METHYLGLYOXAL; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID PEROXIDATION; LIVER; MALE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SPLEEN;

ANIMALS; ANTIOXIDANTS; CATALASE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; GLUTATHIONE TRANSFERASE; LACTOYLGLUTATHIONE LYASE; LIPID PEROXIDATION; LIVER; MALE; MICE; MICE, INBRED STRAINS; OXIDATIVE STRESS; PYRUVALDEHYDE; SUPEROXIDE DISMUTASE; THIOLESTER HYDROLASES;

ANIMALIA;

EID: 0031452880     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(97)00087-8     Document Type: Article

References (54)

1. Aebi, H., 1984. Catalase in vitro. In: Colowick, S.P., Kaplan, N.O. (Eds.), Methods in Enzymology. vol. 105, Academic Press, New York, pp. 121-126.
2. Atkins T.W., Thornalley P.J. Modification of the red blood cell glyoxalase system in genetically (ob/ob) and streptozotocin induced diabetic mice. Diabetes Res. 11:1989;125-129.
3. Baskaran S., Balasubramanium K.A. Effect of methylglyoxal on protein thiol and amino groups in isolated rat enterocytes and colonocytes and activity of various brush border enzymes. Indian J. Biochem. Biophys. 27:1990;13-17.
4. Beyer E.B., Aguilar J.S., Bernardo S.D., Cavazzoni M., Fato R., Fiorentini D., Galli M.C., Setti M., Landi L., Lenaz G. The role of DT-diaphorase in the maintenance of the reduced antioxidant form of CoQ in membrane systems. Proc. Natl. Acad. Sci. USA. 93:1996;2528-2532.
5. Bone S., Lewis T.J., Pethig R., Szent- Györgyi A. Electronic properties of some protein-methylglyoxal complexes. Proc. Natl. Acad. Sci. USA. 75:1978;315-318.
6. Braun L., Garzo T., Mandl J., Kalapos M.P. Methylglyoxal and cell viability. Int. J. Biochem. 26(8):1994;987-990.
7. Bronzetti G., Corsi C., Del Chiaro D., Boccardo P., Vellosi R., Rossi F., Paolini M., Cantelli Forti G. Methylglyoxal: genotoxicity studies and its effect in vivo on the hepatic microsomal mono-oxygenase system of mouse. Mutagenesis. 2:1987;275-277.
8. Cohen G.M., d'Arcy Doherty M. Free radical mediated cell toxicity by redox cycling chemicals. Br. J. Cancer. 55:1987;46s-52s.
9. Dianzani M.U. Biological activity of methylglyoxal and related aldehydes. Ciba Found. Symp. 67:1978;245-270.
10. Ernster L., Danielson L., Ljunggren M. DT-diaphorase, I. Purification from the soluble fraction of rat liver cytoplasm. Biochim. Biophys. Acta. 58:1962;171-188.
11. Furihata C., Sato Y., Matsushima T., Tatematsu M. Induction of ornithine decarboxylase and DNA synthesis in stomach mucosa. Carcinogenesis. 6:1985;91-94.
12. Habig W.H., Pabst M.J., Jacoby W.B. Glutathione-S-transferase: The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249:1974;7130-7139.
13. Halder J., Ray M., Ray S. Inhibition of glycolysis and mitochondrial respiration in Ehrlich ascites carcinoma cells by methylglyoxal. Int. J. Cancer. 54:1993;443-449.
14. Kalapos M.P., Garzo T., Antoni F., Mandl J. Accumulation of S-D-lactoylglutathione and transient decrease of glutathione level caused by methylglyoxal load in isolated hepatocytes. Biochim. Biophys. Acta. 1135:1992;159-164.
15. Kalapos M.P., Littauer A., de Groot H. Has reactive oxygen a role in methylglyoxal toxicity? A study on cultured rat hepatocytes. Arch. Toxicol. 67:1993;369-372.
16. Kalapos M.P. Accumulation of phenols in isolated hepatocytes after pretreatment with methylglyoxal. Toxicol. Lett. 58:1991;181-191.
17. Kalapos M.P. Mechanisms leading to complications in diabetes mellitus: pathological role of alpha-oxoaldehydes. Biochem. Educ. 20:1992;27-29.
18. Kalapos M.P. Methylglyoxal toxicity in mammals. Toxicol. Lett. 73:1994;3-24.
19. Kappus H. Overview of enzyme systems involved in bioreduction of drugs and in redox cycling. Biochem. Pharmacol. 35:1986;1-6.
20. Kon H., Szent-Györgyi A. Charge transfer between and carbonyl. Proc. Natl. Acad. Sci. USA. 69:1973;3139-3140.
21. Konings A.W.T., Drijver E.B. Radiation effects on membranes. I. Vitamin E deficiency and lipid peroxidation. Radiat. Res. 80:1979;494-501.
22. Kun E. Inhibition of succinic dehydrogenase by methylglyoxal. J. Biol. Chem. 187:1950;289-297.
23. Leocini G., Maresca M., Buzzi E. Inhibition of the glycolytic pathway by methylglyoxal in human platelets. Cell Biochem. Funct. 7:1989;65-70.
24. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
25. Marklund S., Marklund G. Involvement of superoxide anion radical in autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 47:1974;469-474.
26. McCartney M.A. Effect of glutathione depletion on morphine toxicity in mice. Biochem. Pharmacol. 38:1988;207-209.
27. McLaughlin J.A., Pethig R., Szent-Györgyi A. Spectroscopic studies of the protein- methylglyoxal adduct. Proc. Natl. Acad. Sci. USA. 77:1980;949-951.
28. Meister A. Glutathione metabolism and its selective modification. J. Biol. Chem. 263:1988;17205-17208.
29. Moron M.A., Dipierre I.W., Mannervick B. Levels of glutathione, glutathione reductase and glutathione-S-transferase activities in rat lung and liver. Biochim. Biophys. Acta. 582:1979;67-78.
30. Nagao M., Fujita Y., Wakabayashi K., Nukaya H., Kosuge T., Sugimura T. Mutagens in coffee and other beverages. Environ. Health Perspect. 67:1986;89-91.
31. Otsuka H., Együd L.G. Nucleic acid and protein synthesis of malignant ascites cells in the presence of liver extract and methylglyoxal. Cancer Res. 27:1967;1498-1499.
32. Passeyre D., Dolder A., Artigou J.Y., Wandscheer J.C., Descatoire V., Degott C., Benhamou J.P. Effect of fasting on metabolite-mediated hepatotoxicity in the rat. Gastroenterology. 77:1979;264-271.
33. Penninckx M.J., Jaspers C.J., Legrain M.J. The glutathione dependent glyoxalase pathway in yeast Saccharomyces cerevisiae. A vital defence line against methylglyoxal producing during glycerol catabolism. J. Biol. Chem. 258:1983;6030-6038.
34. Pethig R., Szent-Györgyi A. Electronic properties of the casein-methylglyoxal complex. Proc. Natl. Acad. Sci. USA. 74:1977;226-228.
35. Racker E. The mechanism of action of glyoxalase. J. Biol. Chem. 190:1951;685-696.
36. Ray M., Ray S. Purification and partial characterization of a methylglyoxal reductase from goat liver. Biochim. Biophys. Acta. 802:1984;119-127.
37. Reitman S., Frankal S. A colorimetric method for the determination of serum oxalacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol. 28:1957;53-56.
38. Revesz, L., Edgren, M., Nishidai, T., 1984. Mechanism of inherent radioprotection in mammalian cells. In: Sugahara, T. (Ed.), Modifications of Radiosensitivity In Cancer Treatment. Academic Press, New York, pp. 13-29.
39. Sharma-Luthra R., Kale R.K. Age related changes in the activity of the glyoxalase system. Mech. Ageing Dev. 73:1994;39-45.
40. +2. Rad. Phy. Chem. 43(6):1994;563-567.
41. Sugimura T., Sato S. Mutagens-carcinogens in foods. Cancer Res. 43:1983;2415s-2421s.
42. Szent-Györgyi A., McLaughlin J.A. Interaction of glyoxal and methylglyoxal with biogenic amines. Proc. Natl. Acad. Sci. USA. 72:1975;1610-1611.
43. Szent-Györgyi A. Protein radicals, regulation and cancer., Int. J. Quantum Chem. Quantum Biol. Symp. 4:1977;179-184.
44. 32P-Post labelling analysis of a DNA adduct and N2-acetyl derivative of guanine formed in vitro by methylglyoxal and hydrogen peroxide in combination. Mut. Res. 351(2):1996;173-180.
45. Thornalley P.J. The glyoxalase system: developments towards functional characterization of a metabolic pathway fundamental to biological life. Biochem J. 269:1990;1-11.
46. Thornalley P.J. The glyoxalase system in health and disease. Mol. Aspects. Med. 14:1993;287-371.
47. Thornalley P.J. Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids and enzymatic detoxification-a role in pathogenesis and antiproliferative chemotherapy. Gen. Pharmacol. 27(4):1996;565-573.
48. van Kuijik F.J.G.M., Sevanian A., Handleman G.J., Dratz E.G. A new role for phospholipase A2: Protection of membranes from lipid peroxidation damage. Trend. Biochem. Sci. 12:1987;31-34.
49. Vander Jagt, D.L., Hunsaker, L.A., 1993. Substrate specifity of reduced and oxidized forms of human aldosereductase. In: Enzymol. Mol. Biol. Carbonyl Metab. Plenum Press, New York, vol. 4, pp. 279-288.
50. Vander Jagt D.L., Robinson B., Taylor K.K., Hunsaker L.A. Reduction of trioses by NADPH- dependent aldo-keto reductases. J. Biol. Chem. 267:1992;4364-4370.
51. Varshney R., Kale R.K. Modulation of radiation induced lipid peroxidation by phospholipase A2 and calmodulin antagonists: Relevance to detoxification. Radiat. Phys. Chem. 45(4):1995;671-675.
52. Videla L.A., Fernandez V., de Marinis A., Fernandez N., Valenzuela A. Liver lipoperoxidative pressure and glutathione status following acetaldehyde and aliphatic alcohol pretreatments in the rat. Biochem. Biophys. Res. Commun. 104:1982;965-970.
53. Vogt-Moller P. Is avitaminosis B1 an intoxication by methylglyoxal? Biochem J. 25:1931;418-421.
54. Yim H., Kang S., Hah Y., Chock P.B., Yim M.B. Free radicals generated during the glycation reaction of amino acids by methylglyoxal. J. Biol. Chem. 270:1995;28228-28233.