Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells

Free Radical Biology and Medicine

Volumn 31, Issue 3, 2001, Pages 321-330

  Wang, Tsu Shing ^a   Hsu, Tsung Yang ^a   Chung, Chiao Hui ^a   Wang, Alexander S S ^b   Bau, Da Tian ^b,c   Jan, Kun Yan ^b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b ACADEMIA SINICA   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

8OH dG; Arsenic; Comet assay; DNA damages; DNA protein cross links; Free radicals; Hydroxyl radicals; Hypochlorous acid; Peroxynitrite

Indexed keywords

1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID TETRA(ACETOXYMETHYL ESTER); 4 AMINOBENZOHYDRAZIDE; ACETIC ACID DERIVATIVE; ARSENIC TRIOXIDE; ARSENITE SODIUM; BENZOIC ACID DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; CATALASE; DIETHYLTHIOCARBAMATE; DNA GLYCOSYLTRANSFERASE; ENZYME INHIBITOR; FORMAMIDOPYRIDINE; HYDROXYL RADICAL; HYPOCHLOROUS ACID; MYELOPEROXIDASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; PEROXYNITRITE; PROTEINASE K; PYRIDINE DERIVATIVE; QUIN 2; S METHYLTHIOCITRULLINE; SALICYLHYDROXAMIC ACID; SUPEROXIDE DISMUTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CHO CELL; CONTROLLED STUDY; DNA ADDUCT; DNA CROSS LINKING; DNA STRAND BREAKAGE; EXCISION REPAIR; HUMAN; HUMAN CELL; LEUKEMIA CELL; MAMMAL CELL; OXIDATION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA;

ANIMALS; ARSENITES; CELL LINE; CELL SURVIVAL; CHO CELLS; CRICETINAE; CROSS-LINKING REAGENTS; DNA; DNA ADDUCTS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENDOPEPTIDASE K; FREE RADICALS; HL-60 CELLS; HUMANS; N-GLYCOSYL HYDROLASES; SODIUM COMPOUNDS;

CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 0035426039     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00581-0     Document Type: Article

References (48)

1. Blackfoot disease in Taiwan: A 30-year follow-up study
2. Ingested inorganic arsenic and prevalence of diabetes mellitus
3. Increased prevalence of hypertension and long-term arsenic exposure
4. Ecological correlation between arsenic level in well water and age-adjusted mortality from malignant neoplasms
5. Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water
6. Sodium arsenite enhances the cytotoxicity clastogenicity and 6-thioguanine-resistant mutagenicity of ultraviolet light in Chinese hamster ovary cells
7. Posttreatment with sodium arsenite alters the mutational spectrum induced by ultraviolet light irradiation in Chinese hamster ovary cells
8. Study of arsenic mutagenesis using the plasmid shuttle vector pZ189 propagated in DNA repair proficient human cells
9. Mutagenicity of arsenic in mammalian cells: Role of reactive oxygen species
10. Effects of arsenite on the DNA repair of UV-irradiated Chinese hamster ovary cells
11. Differential effects of luminol nickel and arsenite on the rejoining of ultraviolet light and alkylation-induced DNA breaks
12. Comparative investigations of the genotoxic effects of metals in the single cells gel (SCG) assay and the sister chromatid exchange (SCE) test
13. Arsenic-induced DNA-strand breaks associated with DNA-protein cross-links in human fetal lung fibroblasts
14. Arsenite induces DNA-protein cross-links and cytokeratin expression in the WRL-68 human hepatic cell line
15. NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells
16. DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells
17. Arsenite stimulates poly (ADP-ribosylation) by generation of nitric oxide
18. The comet moment as a measure of DNA damage in the comet assay
19. 8-Oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity
20. Detection of cross-links with the comet assay in relationship to genotoxicity and cytotoxicity
21. Calcium-dependent nitric oxide production is involved in arsenite-induced micronuclei
22. Differential activation of ERK JNK/SAPK and P38/CSBP/RK map kinase family members during the cellular response to arsenite
23. The tumor promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase
24. Arsenic mediates cell proliferation and gene expression in the bladder epithelium: Association with activating protein-1 transactivation
25. Mechanisms of arsenic carcinogenicity: Genetic or epigenetic mechanisms?
26. Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in inner Mongolia
27. Clinicopathological features of bladder cancer associated with chronic exposure to arsenic
28. Relationship of urinary arsenic to intake estimates and a biomarker of effect bladder cell micronuclei
29. Micronuclei in exfoliated bladder cells among individuals chronically exposed to arsenic in drinking water
30. Decrease in bladder cell micronucleus prevalence after intervention to lower the concentration of arsenic in drinking water
31. Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen chlorine and nitrogen species: Measurement mechanism and the effects of nutrition
32. Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA
33. Hypochlorous acid-induced DNA base modification: Potentiation by nitrite: Biomarkers of DNA damage by reactive oxygen species
34. Nitrite-induced deamination and hypochlorite-induced oxidation of DNA in intact human respiratory tract epithelial cells
35. Expression of granule protein mRNAs in acute promyelocytic leukemia
36. Expression of azurophil and specific granule proteins during differentiation of NB4 cells in neutrophils
37. Myeloperoxidase is involved in H2O2-induced apoptosis of HL-60 human leukemia cells
38. Mechanism of comutagenesis of sodium arsenite with n-methyl-n-nitrosourea
39. Arsenite enhances DNA double-strand breaks and cell killing on methyl methanesulfonate-treated cells by inhibiting the excision of alkali-labile sites
40. Arsenite retards DNA break rejoining by inhibiting DNA ligation
41. Delay of the excision of UV light-induced DNA adducts is involved in the coclastogenicity of UV light plus arsenite
42. Interaction of arsenic(III) with nucleotide excision repair in UV-irradiated human fibroblasts
43. Endogenous DNA damage as related to cancer and aging
44. Nitric oxide is involved in arsenite inhibition of pyrimidine dimer excision
45. Dithiothreitol enhances arsenic trioxide-induced apoptosis in NB4 cells
46. Low levels of arsenic trioxide stimulate proliferative signals in primary vascular cells without activating stress effector pathways
47. Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species
48. Involvement of calcium-dependent protein kinase C in arsenite-induced genotoxicity in Chinese hamster ovary cells