-
1
-
-
0035795411
-
Role of diacylglycerol kinase α in the attenuation of receptor signaling
-
Sanjuán, M.A.; Jones, D.R.; Izquierdo, M.; Mérida, I. Role of diacylglycerol kinase α in the attenuation of receptor signaling. J. Cell Biol. 2001, 153, 207-220.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 207-220
-
-
Sanjuán, M.A.1
Jones, D.R.2
Izquierdo, M.3
Mérida, I.4
-
2
-
-
0032514484
-
Protein kinase C regulates the nuclear localization of diacylglycerol kinase
-
Topham, M.K.; Bunting, M.; Zimmerman, G.A.; McIntyre, T.M.; Blackshear, P.J.; Prescott, S.M. Protein kinase C regulates the nuclear localization of diacylglycerol kinase-ζ. Nature 1998, 394, 697-700.
-
(1998)
Nature
, vol.394
, pp. 697-700
-
-
Topham, M.K.1
Bunting, M.2
Zimmerman, G.A.3
McIntyre, T.M.4
Blackshear, P.J.5
Prescott, S.M.6
-
3
-
-
66349133941
-
Signaling at the membrane interface by the DGK/SK enzyme family
-
Raben, D.M.; Wattenberg, B.W. Signaling at the membrane interface by the DGK/SK enzyme family. J. Lipid Res. 2008, 50, S35-S39.
-
(2008)
J. Lipid Res.
, vol.50
-
-
Raben, D.M.1
Wattenberg, B.W.2
-
4
-
-
0037189475
-
Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization
-
Sugiura, M.; Kono, K.; Liu, H.; Shimizugawa, T.; Minekura, H.; Spiegel, S.; Kohama, T. Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization. J. Biol. Chem. 2002, 277, 23294-23300.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23294-23300
-
-
Sugiura, M.1
Kono, K.2
Liu, H.3
Shimizugawa, T.4
Minekura, H.5
Spiegel, S.6
Kohama, T.7
-
5
-
-
41149157492
-
Diacylglycerol kinases: At the hub of cell signalling
-
Merida, I.; Avila-Flores, A.; Merino, E. Diacylglycerol kinases: At the hub of cell signalling. Biochem. J. 2008, 410, 631-631.
-
(2008)
Biochem. J.
, vol.410
, pp. 631
-
-
Merida, I.1
Avila-Flores, A.2
Merino, E.3
-
6
-
-
0033887478
-
Signaling and subcellular targeting by membrane-binding domains
-
Hurley, J.H.; Misra, S. Signaling and subcellular targeting by membrane-binding domains. Annu. Rev. Biophys. Biomol. Struct. 2000, 29, 49-79.
-
(2000)
Annu. Rev. Biophys. Biomol. Struct.
, vol.29
, pp. 49-79
-
-
Hurley, J.H.1
Misra, S.2
-
7
-
-
0034637434
-
Subtype-specific translocation of diacylglycerol kinase alpha and gamma and its correlation with protein kinase C
-
Shirai, Y.; Segawa, S.; Kuriyama, M.; Goto, K.; Sakai, N.; Saito, N. Subtype-specific translocation of diacylglycerol kinase alpha and gamma and its correlation with protein kinase C. J. Biol. Chem. 2000, 275, 24760-24766.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24760-24766
-
-
Shirai, Y.1
Segawa, S.2
Kuriyama, M.3
Goto, K.4
Sakai, N.5
Saito, N.6
-
8
-
-
0037119466
-
Dynamics of diacylglycerol kinase ζ translocation in living T-cells
-
Santos, T.; Carrasco, S.; Jones, D.R.; Mérida, I.; Eguinoa, A. Dynamics of diacylglycerol kinase ζ translocation in living T-cells. J. Biol. Chem. 2002, 277, 30300-30309.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30300-30309
-
-
Santos, T.1
Carrasco, S.2
Jones, D.R.3
Mérida, I.4
Eguinoa, A.5
-
9
-
-
15444373874
-
Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C
-
Van Baal, J.; de Widt, J.; Divecha, N.; van Blitterswijk, W.J. Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C. J. Biol. Chem. 2005, 280, 9870-9878.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9870-9878
-
-
van Baal, J.1
de Widt, J.2
Divecha, N.3
van Blitterswijk, W.J.4
-
10
-
-
33846834013
-
Targeting of diacylglycerol degradation to M1 muscarinic receptors by β-arrestins
-
Nelson, C.D.; Perry, S.J.; Regier, D.S.; Prescott, S.M.; Topham, M.K.; Lefkowitz, R.J. Targeting of diacylglycerol degradation to M1 muscarinic receptors by β-arrestins. Science 2007, 315, 663-666.
-
(2007)
Science
, vol.315
, pp. 663-666
-
-
Nelson, C.D.1
Perry, S.J.2
Regier, D.S.3
Prescott, S.M.4
Topham, M.K.5
Lefkowitz, R.J.6
-
11
-
-
23344435425
-
Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase
-
Yakubchyk, Y.; Abramovici, H.; Maillet, J.-C.; Daher, E.; Obagi, C.; Parks, R.J.; Topham, M.K.; Gee, S.H. Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase ζ. Mol. Cell. Biol. 2005, 25, 7289-7302.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 7289-7302
-
-
Yakubchyk, Y.1
Abramovici, H.2
Maillet, J.-C.3
Daher, E.4
Obagi, C.5
Parks, R.J.6
Topham, M.K.7
Gee, S.H.8
-
12
-
-
0034602168
-
A domain with homology to neuronal calcium sensors is required for calcium-dependent activation of diacylglycerol kinase α
-
Jiang, Y.; Qian, W.; Hawes, J.W.; Walsh, J.P. A domain with homology to neuronal calcium sensors is required for calcium-dependent activation of diacylglycerol kinase α. J. Biol. Chem. 2000, 275, 34092-34099.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34092-34099
-
-
Jiang, Y.1
Qian, W.2
Hawes, J.W.3
Walsh, J.P.4
-
13
-
-
84863332129
-
Calcium negatively regulates an intramolecular interaction between the N-terminal recoverin homology and EF-hand motif domains and the C-terminal C1 and catalytic domains of diacylglycerol kinase α
-
Takahashi, M.; Yamamoto, T.; Sakai, H.; Sakane, F. Calcium negatively regulates an intramolecular interaction between the N-terminal recoverin homology and EF-hand motif domains and the C-terminal C1 and catalytic domains of diacylglycerol kinase α. Biochem. Biophys. Res. Commun. 2012, 423, 571-576.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.423
, pp. 571-576
-
-
Takahashi, M.1
Yamamoto, T.2
Sakai, H.3
Sakane, F.4
-
14
-
-
36849005359
-
Role of the diacylglycerol kinase α-conserved domains in membrane targeting in intact T cells
-
Merino, E.; Sanjuán, M.A.; Moraga, I.; Ciprés, A.; Mérida, I. Role of the diacylglycerol kinase α-conserved domains in membrane targeting in intact T cells. J. Biol. Chem. 2007, 282, 35396-35404.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35396-35404
-
-
Merino, E.1
Sanjuán, M.A.2
Moraga, I.3
Ciprés, A.4
Mérida, I.5
-
15
-
-
0031033007
-
EF-hand motifs of alpha, beta and gamma isoforms of diacylglycerol kinase bind calcium with different affinities and conformational changes
-
Yamada, K.; Sakane, F.; Matsushima, N.; Kanoh, H. EF-hand motifs of alpha, beta and gamma isoforms of diacylglycerol kinase bind calcium with different affinities and conformational changes. Biochem. J. 1997, 321, 59-64.
-
(1997)
Biochem. J.
, vol.321
, pp. 59-64
-
-
Yamada, K.1
Sakane, F.2
Matsushima, N.3
Kanoh, H.4
-
16
-
-
84871818683
-
Induction of filopodia-like protrusions in N1E-115 neuroblastoma cells by diacylglycerol kinase γ independent of its enzymatic activity: Potential novel function of the C-terminal region containing the catalytic domain of diacylglycerol kinase γ
-
Tanino, F.; Maeda, Y.; Sakai, H.; Sakane, F. Induction of filopodia-like protrusions in N1E-115 neuroblastoma cells by diacylglycerol kinase γ independent of its enzymatic activity: Potential novel function of the C-terminal region containing the catalytic domain of diacylglycerol kinase γ. Mol. Cell. Biochem. 2013, 373, 85-93.
-
(2013)
Mol. Cell. Biochem.
, vol.373
, pp. 85-93
-
-
Tanino, F.1
Maeda, Y.2
Sakai, H.3
Sakane, F.4
-
17
-
-
28844495301
-
Identification and characterization of a novel human type II diacylglycerol kinase, DGKκ
-
Imai, S.; Kai, M.; Yasuda, S.; Kanoh, H.; Sakane, F. Identification and characterization of a novel human type II diacylglycerol kinase, DGKκ. J. Biol. Chem. 2005, 280, 39870-39881.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39870-39881
-
-
Imai, S.1
Kai, M.2
Yasuda, S.3
Kanoh, H.4
Sakane, F.5
-
18
-
-
0029811987
-
Cloning and characterization of a glucocorticoid-induced diacylglycerol kinase
-
Klauck, T.M.; Xu, X.; Mousseau, B.; Jaken, S. Cloning and characterization of a glucocorticoid-induced diacylglycerol kinase. J. Biol. Chem. 1996, 271, 19781-19788.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19781-19788
-
-
Klauck, T.M.1
Xu, X.2
Mousseau, B.3
Jaken, S.4
-
19
-
-
0029877466
-
Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases
-
Sakane, F.; Imai, S.; Kai, M.; Wada, I.; Kanoh, H. Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases. J. Biol. Chem. 1996, 271, 8394-8401.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8394-8401
-
-
Sakane, F.1
Imai, S.2
Kai, M.3
Wada, I.4
Kanoh, H.5
-
20
-
-
42949124488
-
Comprehensive identification of PIP3-regulated PH domains from C. elegans to H. sapiens by model prediction and live imaging
-
Park, W.S.; Heo, W.D.; Whalen, J.H.; O'Rourke, N.A.; Bryan, H.M.; Meyer, T.; Teruel, M.N. Comprehensive identification of PIP3-regulated PH domains from C. elegans to H. sapiens by model prediction and live imaging. Mol. Cell 2008, 30, 381-392.
-
(2008)
Mol. Cell
, vol.30
, pp. 381-392
-
-
Park, W.S.1
Heo, W.D.2
Whalen, J.H.3
O'Rourke, N.A.4
Bryan, H.M.5
Meyer, T.6
Teruel, M.N.7
-
21
-
-
0031565953
-
Distinct specificity in the binding of inositol phosphates by pleckstrin homology domains of pleckstrin, RAC-protein kinase, diacylglycerol kinase and a new 130 kDa protein
-
Takeuchi, H.; Kanematsu, T.; Misumi, Y.; Sakane, F.; Konishi, H.; Kikkawa, U.; Watanabe, Y.; Katan, M.; Hirata, M. Distinct specificity in the binding of inositol phosphates by pleckstrin homology domains of pleckstrin, RAC-protein kinase, diacylglycerol kinase and a new 130 kDa protein. Biochim. Biophys. Acta 1997, 1359, 275-285.
-
(1997)
Biochim. Biophys. Acta
, vol.1359
, pp. 275-285
-
-
Takeuchi, H.1
Kanematsu, T.2
Misumi, Y.3
Sakane, F.4
Konishi, H.5
Kikkawa, U.6
Watanabe, Y.7
Katan, M.8
Hirata, M.9
-
22
-
-
0037144417
-
Phorbol ester-regulated oligomerization of diacylglycerol kinase delta linked to its phosphorylation and translocation
-
Imai, S.; Sakane, F.; Kanoh, H. Phorbol ester-regulated oligomerization of diacylglycerol kinase delta linked to its phosphorylation and translocation. J. Biol. Chem. 2002, 277, 35323-35332.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35323-35332
-
-
Imai, S.1
Sakane, F.2
Kanoh, H.3
-
23
-
-
4744364185
-
The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain
-
Imai, S.-I.; Kai, M.; Yamada, K.; Kanoh, H.; Sakane, F. The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain. Biochem. J. 2004, 382, 957-966.
-
(2004)
Biochem. J.
, vol.382
, pp. 957-966
-
-
Imai, S.-I.1
Kai, M.2
Yamada, K.3
Kanoh, H.4
Sakane, F.5
-
24
-
-
78149336385
-
Zinc binding drives sheet formation by the SAM domain of diacylglycerol kinase δ
-
Knight, M.J.; Joubert, M.K.; Plotkowski, M.L.; Kropat, J.; Gingery, M.; Sakane, F.; Merchant, S.S.; Bowie, J.U. Zinc binding drives sheet formation by the SAM domain of diacylglycerol kinase δ. Biochemistry 2010, 49, 9667-9676.
-
(2010)
Biochemistry
, vol.49
, pp. 9667-9676
-
-
Knight, M.J.1
Joubert, M.K.2
Plotkowski, M.L.3
Kropat, J.4
Gingery, M.5
Sakane, F.6
Merchant, S.S.7
Bowie, J.U.8
-
25
-
-
0031007843
-
Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in rat retina
-
Kohyama-Koganeya, A.; Watanabe, M.; Hotta, Y. Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in rat retina. FEBS Lett. 1997, 409, 258-264.
-
(1997)
FEBS Lett.
, vol.409
, pp. 258-264
-
-
Kohyama-Koganeya, A.1
Watanabe, M.2
Hotta, Y.3
-
26
-
-
0035836345
-
Diacylglycerol kinase epsilon regulates seizure susceptibility and long-term potentiation through arachidonoyl-inositol lipid signaling
-
De Turco, R.E.B.; Tang, W.; Topham, M.K.; Sakane, F.; Marcheselli, V.L.; Chen, C.; Taketomi, A.; Prescott, S.M.; Bazan, N.G. Diacylglycerol kinase epsilon regulates seizure susceptibility and long-term potentiation through arachidonoyl-inositol lipid signaling. Proc. Natl. Acad. Sci. USA 2001, 98, 4740-4745.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4740-4745
-
-
de Turco, R.E.B.1
Tang, W.2
Topham, M.K.3
Sakane, F.4
Marcheselli, V.L.5
Chen, C.6
Taketomi, A.7
Prescott, S.M.8
Bazan, N.G.9
-
27
-
-
0019829515
-
The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets
-
Prescott, S.M.; Majerus, P.W. The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets. J. Biol. Chem. 1981, 256, 579-582.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 579-582
-
-
Prescott, S.M.1
Majerus, P.W.2
-
28
-
-
80054080494
-
Regulation and functions of diacylglycerol kinases
-
Shulga, Y.V.; Topham, M.K.; Epand, R.M. Regulation and functions of diacylglycerol kinases. Chem. Rev. 2011, 111, 6186-6208.
-
(2011)
Chem. Rev.
, vol.111
, pp. 6186-6208
-
-
Shulga, Y.V.1
Topham, M.K.2
Epand, R.M.3
-
29
-
-
34250665428
-
Proteomics identification of sorting Nexin 27 as a diacylglycerol kinase ζ-associated protein
-
Rincon, E.; Santos, T.; Ávila-Flores, A.; Albar, J.P.; Lalioti, V.; Lei, C.; Hong, W.; Mérida, I. Proteomics identification of sorting Nexin 27 as a diacylglycerol kinase ζ-associated protein. Mol. Cell. Proteomics 2007, 6, 1073-1087.
-
(2007)
Mol. Cell. Proteomics
, vol.6
, pp. 1073-1087
-
-
Rincon, E.1
Santos, T.2
Ávila-Flores, A.3
Albar, J.P.4
Lalioti, V.5
Lei, C.6
Hong, W.7
Mérida, I.8
-
30
-
-
0035854664
-
Interaction of γ1-syntrophin with diacylglycerol kinase-ζ
-
Hogan, A.; Shepherd, L.; Chabot, J.; Quenneville, S.; Prescott, S.M.; Topham, M.K.; Gee, S.H. Interaction of γ1-syntrophin with diacylglycerol kinase-ζ. J. Biol. Chem. 2001, 276, 26526-26533.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26526-26533
-
-
Hogan, A.1
Shepherd, L.2
Chabot, J.3
Quenneville, S.4
Prescott, S.M.5
Topham, M.K.6
Gee, S.H.7
-
31
-
-
0345687302
-
Diacylglycerol kinase-ζ localization in skeletal muscle is regulated by phosphorylation and interaction with syntrophins
-
Abramovici, H.; Hogan, A.B.; Obagi, C.; Topham, M.K.; Gee, S.H. Diacylglycerol kinase-ζ localization in skeletal muscle is regulated by phosphorylation and interaction with syntrophins. Mol. Biol. Cell 2003, 14, 4499-4511.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 4499-4511
-
-
Abramovici, H.1
Hogan, A.B.2
Obagi, C.3
Topham, M.K.4
Gee, S.H.5
-
32
-
-
34250320543
-
Morphological changes and spatial regulation of diacylglycerol kinase-ζ, syntrophins, and Rac1 during myoblast fusion
-
Abramovici, H.; Gee, S.H. Morphological changes and spatial regulation of diacylglycerol kinase-ζ, syntrophins, and Rac1 during myoblast fusion. Cell Motil. Cytoskeleton 2007, 64, 549-567.
-
(2007)
Cell Motil. Cytoskeleton
, vol.64
, pp. 549-567
-
-
Abramovici, H.1
Gee, S.H.2
-
33
-
-
0035937193
-
Diacylglycerol kinase ζ in hypothalamus interacts with long form leptin receptor
-
Liu, Z.; Chang, G.-Q.; Leibowitz, S.F. Diacylglycerol kinase ζ in hypothalamus interacts with long form leptin receptor. J. Biol. Chem. 2001, 276, 5900-5907.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5900-5907
-
-
Liu, Z.1
Chang, G.-Q.2
Leibowitz, S.F.3
-
34
-
-
67349239306
-
Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance
-
Kim, K.; Yang, J.; Zhong, X.-P.; Kim, M.-H.; Kim, Y.S.; Lee, H.W.; Han, S.; Choi, J.; Han, K.; Seo, J.; et al. Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. EMBO J. 2009, 28, 1170-1179.
-
(2009)
EMBO J.
, vol.28
, pp. 1170-1179
-
-
Kim, K.1
Yang, J.2
Zhong, X.-P.3
Kim, M.-H.4
Kim, Y.S.5
Lee, H.W.6
Han, S.7
Choi, J.8
Han, K.9
Seo, J.10
-
35
-
-
78650886564
-
DGKι regulates presynaptic release during mGluR-dependent LTD
-
Yang, J.; Seo, J.; Nair, R.; Han, S.; Jang, S.; Kim, K.; Han, K.; Paik, S.K.; Choi, J.; Lee, S.; et al. DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J. 2011, 30, 165-180.
-
(2011)
EMBO J.
, vol.30
, pp. 165-180
-
-
Yang, J.1
Seo, J.2
Nair, R.3
Han, S.4
Jang, S.5
Kim, K.6
Han, K.7
Paik, S.K.8
Choi, J.9
Lee, S.10
-
36
-
-
0030889241
-
Cloning of a novel human diacylglycerol kinase (DGKtheta) containing three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain
-
Houssa, B.; Schaap, D.; van der Wal, J.; Goto, K.; Kondo, H.; Yamakawa, A.; Shibata, M.; Takenawa, T.; Van Blitterswijk, W.J. Cloning of a novel human diacylglycerol kinase (DGKtheta) containing three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. J. Biol. Chem. 1997, 272, 10422-10428.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10422-10428
-
-
Houssa, B.1
Schaap, D.2
van der Wal, J.3
Goto, K.4
Kondo, H.5
Yamakawa, A.6
Shibata, M.7
Takenawa, T.8
van Blitterswijk, W.J.9
-
37
-
-
2942659717
-
Structure-activity relationship of diacylglycerol kinase theta
-
Los, A.P.; van Baal, J.; de Widt, J.; Divecha, N.; van Blitterswijk, W.J. Structure-activity relationship of diacylglycerol kinase theta. Biochim. Biophys. Acta 2004, 1636, 169-174.
-
(2004)
Biochim. Biophys. Acta
, vol.1636
, pp. 169-174
-
-
Los, A.P.1
van Baal, J.2
de Widt, J.3
Divecha, N.4
van Blitterswijk, W.J.5
-
38
-
-
33750334731
-
Diacylglycerol kinase δ regulates protein kinase C and epidermal growth factor receptor signaling
-
Crotty, T.; Cai, J.; Sakane, F.; Taketomi, A.; Prescott, S.M.; Topham, M.K. Diacylglycerol kinase δ regulates protein kinase C and epidermal growth factor receptor signaling. Proc. Natl. Acad. Sci. USA 2006, 103, 15485-15490.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15485-15490
-
-
Crotty, T.1
Cai, J.2
Sakane, F.3
Taketomi, A.4
Prescott, S.M.5
Topham, M.K.6
-
39
-
-
33750093594
-
T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-[alpha]
-
Zha, Y.; Marks, R.; Ho, A.W.; Peterson, A.C.; Janardhan, S.; Brown, I.; Praveen, K.; Stang, S.; Stone, J.C.; Gajewski, T.F. T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-[alpha]. Nat. Immunol. 2006, 7, 1166-1173.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1166-1173
-
-
Zha, Y.1
Marks, R.2
Ho, A.W.3
Peterson, A.C.4
Janardhan, S.5
Brown, I.6
Praveen, K.7
Stang, S.8
Stone, J.C.9
Gajewski, T.F.10
-
40
-
-
0037077135
-
Transcriptional mechanisms underlying lymphocyte tolerance
-
Macián, F.; Garci{dotless}́a-Cózar, F.; Im, S.-H.; Horton, H.F.; Byrne, M.C.; Rao, A. Transcriptional mechanisms underlying lymphocyte tolerance. Cell 2002, 109, 719-731.
-
(2002)
Cell
, vol.109
, pp. 719-731
-
-
McIán, F.1
García-Cózar, F.2
Im, S.-H.3
Horton, H.F.4
Byrne, M.C.5
Rao, A.6
-
41
-
-
33750094147
-
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy
-
Olenchock, B.A.; Guo, R.; Carpenter, J.H.; Jordan, M.; Topham, M.K.; Koretzky, G.A.; Zhong, X.-P. Disruption of diacylglycerol metabolism impairs the induction of T cell anergy. Nat. Immunol. 2006, 7, 1174-1181.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1174-1181
-
-
Olenchock, B.A.1
Guo, R.2
Carpenter, J.H.3
Jordan, M.4
Topham, M.K.5
Koretzky, G.A.6
Zhong, X.-P.7
-
42
-
-
84868686754
-
FoxO-dependent regulation of diacylglycerol kinase α gene expression
-
Martínez-Moreno, M.; García-Liévana, J.; Soutar, D.; Torres-Ayuso, P.; Andrada, E.; Zhong, X.-P.; Koretzky, G.A.; Mérida, I.; Ávila-Flores, A. FoxO-dependent regulation of diacylglycerol kinase α gene expression. Mol. Cell. Biol. 2012, 32, 4168-4180.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 4168-4180
-
-
Martínez-Moreno, M.1
García-Liévana, J.2
Soutar, D.3
Torres-Ayuso, P.4
Andrada, E.5
Zhong, X.-P.6
Koretzky, G.A.7
Mérida, I.8
Ávila-Flores, A.9
-
43
-
-
84871885298
-
Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo
-
Zheng, Y.; Zha, Y.; Driessens, G.; Locke, F.; Gajewski, T.F. Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo. J. Exp. Med. 2012, 209, 2157-2163.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 2157-2163
-
-
Zheng, Y.1
Zha, Y.2
Driessens, G.3
Locke, F.4
Gajewski, T.F.5
-
44
-
-
67650752137
-
T cell activation
-
Smith-Garvin, J.E.; Koretzky, G.A.; Jordan, M.S. T cell activation. Annu. Rev. Immunol. 2009, 27, 591-619.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 591-619
-
-
Smith-Garvin, J.E.1
Koretzky, G.A.2
Jordan, M.S.3
-
45
-
-
82755190049
-
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling
-
Baldanzi, G.; Pighini, A.; Bettio, V.; Rainero, E.; Traini, S.; Chianale, F.; Porporato, P.E.; Filigheddu, N.; Mesturini, R.; Song, S.; et al. SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling. J. Immunol. 2011, 187, 5941-5951.
-
(2011)
J. Immunol.
, vol.187
, pp. 5941-5951
-
-
Baldanzi, G.1
Pighini, A.2
Bettio, V.3
Rainero, E.4
Traini, S.5
Chianale, F.6
Porporato, P.E.7
Filigheddu, N.8
Mesturini, R.9
Song, S.10
-
46
-
-
0037443550
-
T cell activation in vivo targets diacylglycerol kinase α to the membrane: A novel mechanism for Ras attenuation
-
Sanjuan, M.A.; Pradet-Balade, B.; Jones, D.R.; Martinez-A, C.; Stone, J.C.; Garcia-Sanz, J.A.; Merida, I. T cell activation in vivo targets diacylglycerol kinase α to the membrane: A novel mechanism for Ras attenuation. J. Immunol. 2003, 170, 2877-2883.
-
(2003)
J. Immunol.
, vol.170
, pp. 2877-2883
-
-
Sanjuan, M.A.1
Pradet-Balade, B.2
Jones, D.R.3
Martinez-A, C.4
Stone, J.C.5
Garcia-Sanz, J.A.6
Merida, I.7
-
47
-
-
44449117561
-
Lck-dependent tyrosine phosphorylation of diacylglycerol kinase α regulates its membrane association in T cells
-
Merino, E.; Ávila-Flores, A.; Shirai, Y.; Moraga, I.; Saito, N.; Mérida, I. Lck-dependent tyrosine phosphorylation of diacylglycerol kinase α regulates its membrane association in T cells. J. Immunol. 2008, 180, 5805-5815.
-
(2008)
J. Immunol.
, vol.180
, pp. 5805-5815
-
-
Merino, E.1
Ávila-Flores, A.2
Shirai, Y.3
Moraga, I.4
Saito, N.5
Mérida, I.6
-
48
-
-
81755181127
-
Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immune synapse
-
Gharbi, S.I.; Rincón, E.; Avila-Flores, A.; Torres-Ayuso, P.; Almena, M.; Cobos, M.A.; Albar, J.P.; Mérida, I. Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immune synapse. Mol. Biol. Cell 2011, 22, 4406-4414.
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 4406-4414
-
-
Gharbi, S.I.1
Rincón, E.2
Avila-Flores, A.3
Torres-Ayuso, P.4
Almena, M.5
Cobos, M.A.6
Albar, J.P.7
Mérida, I.8
-
49
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
Zhang, W.; Sloan-Lancaster, J.; Kitchen, J.; Trible, R.P.; Samelson, L.E. LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998, 92, 83-92.
-
(1998)
Cell
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
50
-
-
0030002904
-
Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production
-
Motto, D.G.; Ross, S.E.; Wu, J.; Hendricks-Taylor, L.R.; Koretzky, G.A. Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production. J. Exp. Med. 1996, 183, 1937-1943.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1937-1943
-
-
Motto, D.G.1
Ross, S.E.2
Wu, J.3
Hendricks-Taylor, L.R.4
Koretzky, G.A.5
-
51
-
-
0021917674
-
Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores
-
Imboden, J.B.; Stobo, J.D. Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores. J. Exp. Med. 1985, 161, 446-456.
-
(1985)
J. Exp. Med.
, vol.161
, pp. 446-456
-
-
Imboden, J.B.1
Stobo, J.D.2
-
52
-
-
0031784267
-
Regulation of RasGRP via a phorbol ester-responsive C1 domain
-
Tognon, C.E.; Kirk, H.E.; Passmore, L.A.; Whitehead, I.P.; Der, C.J.; Kay, R.J. Regulation of RasGRP via a phorbol ester-responsive C1 domain. Mol. Cell. Biol. 1998, 18, 6995-7008.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6995-7008
-
-
Tognon, C.E.1
Kirk, H.E.2
Passmore, L.A.3
Whitehead, I.P.4
Der, C.J.5
Kay, R.J.6
-
53
-
-
79959376445
-
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells
-
Quann, E.J.; Liu, X.; Altan-Bonnet, G.; Huse, M. A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells. Nat. Immunol. 2011, 12, 647-654.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 647-654
-
-
Quann, E.J.1
Liu, X.2
Altan-Bonnet, G.3
Huse, M.4
-
54
-
-
33646560593
-
Diacylglycerol and protein kinase D localization during T lymphocyte activation
-
Spitaler, M.; Emslie, E.; Wood, C.D.; Cantrell, D. Diacylglycerol and protein kinase D localization during T lymphocyte activation. Immunity 2006, 24, 535-546.
-
(2006)
Immunity
, vol.24
, pp. 535-546
-
-
Spitaler, M.1
Emslie, E.2
Wood, C.D.3
Cantrell, D.4
-
55
-
-
0034303371
-
RasGRP is essential for mouse thymocyte differentiation and TCR signaling
-
Dower, N.A.; Stang, S.L.; Bottorff, D.A.; Ebinu, J.O.; Dickie, P.; Ostergaard, H.L.; Stone, J.C. RasGRP is essential for mouse thymocyte differentiation and TCR signaling. Nat. Immunol. 2000, 1, 317-321.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 317-321
-
-
Dower, N.A.1
Stang, S.L.2
Bottorff, D.A.3
Ebinu, J.O.4
Dickie, P.5
Ostergaard, H.L.6
Stone, J.C.7
-
56
-
-
0034724201
-
NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta
-
Coudronniere, N.; Villalba, M.; Englund, N.; Altman, A. NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta. Proc. Natl. Acad. Sci. USA 2000, 97, 3394-3399.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3394-3399
-
-
Coudronniere, N.1
Villalba, M.2
Englund, N.3
Altman, A.4
-
57
-
-
18844473151
-
PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes
-
Sun, Z.; Arendt, C.W.; Ellmeier, W.; Schaeffer, E.M.; Sunshine, M.J.; Gandhi, L.; Annes, J.; Petrzilka, D.; Kupfer, A.; Schwartzberg, P.L.; et al. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. Nature 2000, 404, 402-407.
-
(2000)
Nature
, vol.404
, pp. 402-407
-
-
Sun, Z.1
Arendt, C.W.2
Ellmeier, W.3
Schaeffer, E.M.4
Sunshine, M.J.5
Gandhi, L.6
Annes, J.7
Petrzilka, D.8
Kupfer, A.9
Schwartzberg, P.L.10
-
58
-
-
33644772836
-
CARMA1 is required for Akt-mediated NF-kappaB activation in T cells
-
Narayan, P.; Holt, B.; Tosti, R.; Kane, L.P. CARMA1 is required for Akt-mediated NF-kappaB activation in T cells. Mol. Cell. Biol. 2006, 26, 2327-2336.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2327-2336
-
-
Narayan, P.1
Holt, B.2
Tosti, R.3
Kane, L.P.4
-
59
-
-
0346993668
-
CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1
-
Wang, D.; Matsumoto, R.; You, Y.; Che, T.; Lin, X.-Y.; Gaffen, S.L.; Lin, X. CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1. Mol. Cell. Biol. 2004, 24, 164-171.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 164-171
-
-
Wang, D.1
Matsumoto, R.2
You, Y.3
Che, T.4
Lin, X.-Y.5
Gaffen, S.L.6
Lin, X.7
-
60
-
-
8644283766
-
The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse
-
Hara, H.; Bakal, C.; Wada, T.; Bouchard, D.; Rottapel, R.; Saito, T.; Penninger, J.M. The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse. J. Exp. Med. 2004, 200, 1167-1177.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1167-1177
-
-
Hara, H.1
Bakal, C.2
Wada, T.3
Bouchard, D.4
Rottapel, R.5
Saito, T.6
Penninger, J.M.7
-
61
-
-
0037827638
-
Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis
-
Jun, J.E.; Wilson, L.E.; Vinuesa, C.G.; Lesage, S.; Blery, M.; Miosge, L.A.; Cook, M.C.; Kucharska, E.M.; Hara, H.; Penninger, J.M.; et al. Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis. Immunity 2003, 18, 751-762.
-
(2003)
Immunity
, vol.18
, pp. 751-762
-
-
Jun, J.E.1
Wilson, L.E.2
Vinuesa, C.G.3
Lesage, S.4
Blery, M.5
Miosge, L.A.6
Cook, M.C.7
Kucharska, E.M.8
Hara, H.9
Penninger, J.M.10
-
62
-
-
23844509495
-
Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation
-
Medeiros, R.B.; Dickey, D.M.; Chung, H.; Quale, A.C.; Nagarajan, L.R.; Billadeau, D.D.; Shimizu, Y. Protein kinase D1 and the beta 1 integrin cytoplasmic domain control beta 1 integrin function via regulation of Rap1 activation. Immunity 2005, 23, 213-226.
-
(2005)
Immunity
, vol.23
, pp. 213-226
-
-
Medeiros, R.B.1
Dickey, D.M.2
Chung, H.3
Quale, A.C.4
Nagarajan, L.R.5
Billadeau, D.D.6
Shimizu, Y.7
-
63
-
-
34447579251
-
The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2
-
Mor, A.; Campi, G.; Du, G.; Zheng, Y.; Foster, D.A.; Dustin, M.L.; Philips, M.R. The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2. Nat. Cell Biol. 2007, 9, 713-719.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 713-719
-
-
Mor, A.1
Campi, G.2
Du, G.3
Zheng, Y.4
Foster, D.A.5
Dustin, M.L.6
Philips, M.R.7
-
64
-
-
33846438568
-
Regulation of mTOR by phosphatidic acid?
-
Foster, D.A. Regulation of mTOR by phosphatidic acid? Cancer Res. 2007, 67, 1-4.
-
(2007)
Cancer Res.
, vol.67
, pp. 1-4
-
-
Foster, D.A.1
-
65
-
-
68949103681
-
Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells
-
Foster, D.A. Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells. Biochim. Biophys. Acta 2009, 1791, 949-955.
-
(2009)
Biochim. Biophys. Acta
, vol.1791
, pp. 949-955
-
-
Foster, D.A.1
-
66
-
-
0035976615
-
Phosphatidic acid-mediated mitogenic activation of mTOR signaling
-
Fang, Y.; Vilella-Bach, M.; Bachmann, R.; Flanigan, A.; Chen, J. Phosphatidic acid-mediated mitogenic activation of mTOR signaling. Science 2001, 294, 1942-1945.
-
(2001)
Science
, vol.294
, pp. 1942-1945
-
-
Fang, Y.1
Vilella-Bach, M.2
Bachmann, R.3
Flanigan, A.4
Chen, J.5
-
67
-
-
15444378732
-
Modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid
-
Avila-Flores, A. Modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid. J. Biol. Chem. 2005, 280, 10091-10099.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 10091-10099
-
-
Avila-Flores, A.1
-
68
-
-
49249109489
-
Diacylglycerol kinases in immune cell function and self-tolerance
-
Zhong, X.-P.; Guo, R.; Zhou, H.; Liu, C.; Wan, C.-K. Diacylglycerol kinases in immune cell function and self-tolerance. Immunol. Rev. 2008, 224, 249-264.
-
(2008)
Immunol. Rev.
, vol.224
, pp. 249-264
-
-
Zhong, X.-P.1
Guo, R.2
Zhou, H.3
Liu, C.4
Wan, C.-K.5
-
69
-
-
0037163130
-
Regulation of T cell receptor-induced activation of the Ras-ERK pathway by dacylglycerol kinase ζ
-
Zhong, X.-P.; Hainey, E.A.; Olenchock, B.A.; Zhao, H.; Topham, M.K.; Koretzky, G.A. Regulation of T cell receptor-induced activation of the Ras-ERK pathway by dacylglycerol kinase ζ. J. Biol. Chem. 2002, 277, 31089-31098.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31089-31098
-
-
Zhong, X.-P.1
Hainey, E.A.2
Olenchock, B.A.3
Zhao, H.4
Topham, M.K.5
Koretzky, G.A.6
-
70
-
-
0042383362
-
Enhanced T cell responses due to diacylglycerol kinase [zeta] deficiency
-
Zhong, X.-P.; Hainey, E.A.; Olenchock, B.A.; Jordan, M.S.; Maltzman, J.S.; Nichols, K.E.; Shen, H.; Koretzky, G.A. Enhanced T cell responses due to diacylglycerol kinase [zeta] deficiency. Nat. Immunol. 2003, 4, 882-890.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 882-890
-
-
Zhong, X.-P.1
Hainey, E.A.2
Olenchock, B.A.3
Jordan, M.S.4
Maltzman, J.S.5
Nichols, K.E.6
Shen, H.7
Koretzky, G.A.8
-
71
-
-
79954618943
-
Negative regulation of mTOR activation by diacylglycerol kinases
-
Gorentla, B.K.; Wan, C.-K.; Zhong, X.-P. Negative regulation of mTOR activation by diacylglycerol kinases. Blood 2011, 117, 4022-4031.
-
(2011)
Blood
, vol.117
, pp. 4022-4031
-
-
Gorentla, B.K.1
Wan, C.-K.2
Zhong, X.-P.3
-
72
-
-
70349235821
-
Molecular origin and functional consequences of digital signaling and hysteresis during Ras activation in lymphocytes
-
Chakraborty, A.K.; Das, J.; Zikherman, J.; Yang, M.; Govern, C.C.; Ho, M.; Weiss, A.; Roose, J. Molecular origin and functional consequences of digital signaling and hysteresis during Ras activation in lymphocytes. Sci. Signal. 2009, 2, pt2.
-
(2009)
Sci. Signal.
, vol.2
-
-
Chakraborty, A.K.1
Das, J.2
Zikherman, J.3
Yang, M.4
Govern, C.C.5
Ho, M.6
Weiss, A.7
Roose, J.8
-
73
-
-
18944383647
-
A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells
-
Roose, J.P.; Mollenauer, M.; Gupta, V.A.; Stone, J.; Weiss, A. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. Mol. Cell. Biol. 2005, 25, 4426-4441.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 4426-4441
-
-
Roose, J.P.1
Mollenauer, M.2
Gupta, V.A.3
Stone, J.4
Weiss, A.5
-
74
-
-
34147203741
-
Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes
-
Roose, J.P.; Mollenauer, M.; Ho, M.; Kurosaki, T.; Weiss, A. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes. Mol. Cell. Biol. 2007, 27, 2732-2745.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 2732-2745
-
-
Roose, J.P.1
Mollenauer, M.2
Ho, M.3
Kurosaki, T.4
Weiss, A.5
-
75
-
-
58249092059
-
Digital signaling and hysteresis characterize Ras activation in lymphoid cells
-
Das, J.; Ho, M.; Zikherman, J.; Govern, C.; Yang, M.; Weiss, A.; Chakraborty, A.K.; Roose, J.P. Digital signaling and hysteresis characterize Ras activation in lymphoid cells. Cell 2009, 136, 337-351.
-
(2009)
Cell
, vol.136
, pp. 337-351
-
-
Das, J.1
Ho, M.2
Zikherman, J.3
Govern, C.4
Yang, M.5
Weiss, A.6
Chakraborty, A.K.7
Roose, J.P.8
-
76
-
-
79953141058
-
+ T cell functional responses
-
+ T cell functional responses. J. Biol. Chem. 2011, 286, 5254-5265.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 5254-5265
-
-
Riese, M.J.1
Grewal, J.2
Das, J.3
Zou, T.4
Patil, V.5
Chakraborty, A.K.6
Koretzky, G.A.7
-
77
-
-
67349243386
-
Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells
-
Quann, E.J.; Merino, E.; Furuta, T.; Huse, M. Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells. Nat. Immunol. 2009, 10, 627-635.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 627-635
-
-
Quann, E.J.1
Merino, E.2
Furuta, T.3
Huse, M.4
-
78
-
-
0035892735
-
Differential secretion of Fas ligand-or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells
-
Monleón, I.; Martínez-Lorenzo, M.J.; Monteagudo, L.; Lasierra, P.; Taulés, M.; Iturralde, M.; Piñeiro, A.; Larrad, L.; Alava, M.A.; Naval, J.; et al. Differential secretion of Fas ligand-or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells. J. Immunol. 2001, 167, 6736-6744.
-
(2001)
J. Immunol.
, vol.167
, pp. 6736-6744
-
-
Monleón, I.1
Martínez-Lorenzo, M.J.2
Monteagudo, L.3
Lasierra, P.4
Taulés, M.5
Iturralde, M.6
Piñeiro, A.7
Larrad, L.8
Alava, M.A.9
Naval, J.10
-
79
-
-
33846821720
-
Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation
-
Zuccato, E.; Blott, E.J.; Holt, O.; Sigismund, S.; Shaw, M.; Bossi, G.; Griffiths, G.M. Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation. J. Cell Sci. 2007, 120, 191-199.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 191-199
-
-
Zuccato, E.1
Blott, E.J.2
Holt, O.3
Sigismund, S.4
Shaw, M.5
Bossi, G.6
Griffiths, G.M.7
-
80
-
-
79958796052
-
Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes
-
Alonso, R.; Mazzeo, C.; Rodriguez, M.C.; Marsh, M.; Fraile-Ramos, A.; Calvo, V.; Avila-Flores, A.; Merida, I.; Izquierdo, M. Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes. Cell Death Differ. 2011, 18, 1161-1173.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 1161-1173
-
-
Alonso, R.1
Mazzeo, C.2
Rodriguez, M.C.3
Marsh, M.4
Fraile-Ramos, A.5
Calvo, V.6
Avila-Flores, A.7
Merida, I.8
Izquierdo, M.9
-
81
-
-
0023390431
-
Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones
-
Jenkins, M.K.; Pardoll, D.M.; Mizuguchi, J.; Chused, T.M.; Schwartz, R.H. Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones. Proc. Natl. Acad. Sci. USA 1987, 84, 5409-5413.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 5409-5413
-
-
Jenkins, M.K.1
Pardoll, D.M.2
Mizuguchi, J.3
Chused, T.M.4
Schwartz, R.H.5
-
82
-
-
34249736434
-
Molecular mechanisms for adaptive tolerance and other T cell anergy models
-
Choi, S.; Schwartz, R.H. Molecular mechanisms for adaptive tolerance and other T cell anergy models. Semin. Immunol. 2007, 19, 140-152.
-
(2007)
Semin. Immunol.
, vol.19
, pp. 140-152
-
-
Choi, S.1
Schwartz, R.H.2
-
85
-
-
0026667860
-
Transactivation by AP-1 is a molecular target of T cell clonal anergy
-
Kang, S.M.; Beverly, B.; Tran, A.C.; Brorson, K.; Schwartz, R.H.; Lenardo, M.J. Transactivation by AP-1 is a molecular target of T cell clonal anergy. Science 1992, 257, 1134-1138.
-
(1992)
Science
, vol.257
, pp. 1134-1138
-
-
Kang, S.M.1
Beverly, B.2
Tran, A.C.3
Brorson, K.4
Schwartz, R.H.5
Lenardo, M.J.6
-
86
-
-
62249131518
-
Complete but curtailed T-cell response to very low-affinity antigen
-
Zehn, D.; Lee, S.Y.; Bevan, M.J. Complete but curtailed T-cell response to very low-affinity antigen. Nature 2009, 458, 211-214.
-
(2009)
Nature
, vol.458
, pp. 211-214
-
-
Zehn, D.1
Lee, S.Y.2
Bevan, M.J.3
-
87
-
-
78650430984
-
+ T-cell pool
-
+ T-cell pool. Blood 2010, 116, 5548-5559.
-
(2010)
Blood
, vol.116
, pp. 5548-5559
-
-
Smith-Garvin, J.E.1
Burns, J.C.2
Gohil, M.3
Zou, T.4
Kim, J.S.5
Maltzman, J.S.6
Wherry, E.J.7
Koretzky, G.A.8
Jordan, M.S.9
-
88
-
-
78650509025
-
+ memory T cells
-
+ memory T cells. Blood 2010, 116, 5560-5570.
-
(2010)
Blood
, vol.116
, pp. 5560-5570
-
-
Wiehagen, K.R.1
Corbo, E.2
Schmidt, M.3
Shin, H.4
Wherry, E.J.5
Maltzman, J.S.6
-
89
-
-
58849158737
-
+ memory versus effector development
-
+ memory versus effector development. Science 2009, 323, 502-505.
-
(2009)
Science
, vol.323
, pp. 502-505
-
-
Teixeiro, E.1
Daniels, M.A.2
Hamilton, S.E.3
Schrum, A.G.4
Bragado, R.5
Jameson, S.C.6
Palmer, E.7
-
90
-
-
84857463985
-
Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases
-
Shin, J.; O'Brien, T.F.; Grayson, J.M.; Zhong, X.-P. Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases. J. Immunol. 2012, 188, 2111-2117.
-
(2012)
J. Immunol.
, vol.188
, pp. 2111-2117
-
-
Shin, J.1
O'Brien, T.F.2
Grayson, J.M.3
Zhong, X.-P.4
-
91
-
-
67650074206
-
mTOR regulates memory CD8 T-cell differentiation
-
Araki, K.; Turner, A.P.; Shaffer, V.O.; Gangappa, S.; Keller, S.A.; Bachmann, M.F.; Larsen, C.P.; Ahmed, R. mTOR regulates memory CD8 T-cell differentiation. Nature 2009, 460, 108-112.
-
(2009)
Nature
, vol.460
, pp. 108-112
-
-
Araki, K.1
Turner, A.P.2
Shaffer, V.O.3
Gangappa, S.4
Keller, S.A.5
Bachmann, M.F.6
Larsen, C.P.7
Ahmed, R.8
-
92
-
-
67650096912
-
Enhancing CD8 T-cell memory by modulating fatty acid metabolism
-
Pearce, E.L.; Walsh, M.C.; Cejas, P.J.; Harms, G.M.; Shen, H.; Wang, L.-S.; Jones, R.G.; Choi, Y. Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 2009, 460, 103-107.
-
(2009)
Nature
, vol.460
, pp. 103-107
-
-
Pearce, E.L.1
Walsh, M.C.2
Cejas, P.J.3
Harms, G.M.4
Shen, H.5
Wang, L.-S.6
Jones, R.G.7
Choi, Y.8
-
93
-
-
74649085700
-
+ T cell fate by regulating the expression of transcription factors T-bet and eomesodermin
-
+ T cell fate by regulating the expression of transcription factors T-bet and eomesodermin. Immunity 2010, 32, 67-78.
-
(2010)
Immunity
, vol.32
, pp. 67-78
-
-
Rao, R.R.1
Li, Q.2
Odunsi, K.3
Shrikant, P.A.4
-
94
-
-
84860237060
-
Regulation and function of mTOR signalling in T cell fate decisions
-
Chi, H. Regulation and function of mTOR signalling in T cell fate decisions. Nat. Rev. Immunol. 2012, 12, 325-338.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 325-338
-
-
Chi, H.1
-
95
-
-
0032477815
-
Induction of antigen-specific T cell anergy: An early event in the course of tumor progression
-
Staveley-O'Carroll, K.; Sotomayor, E.; Montgomery, J.; Borrello, I.; Hwang, L.; Fein, S.; Pardoll, D.; Levitsky, H. Induction of antigen-specific T cell anergy: An early event in the course of tumor progression. Proc. Natl. Acad. Sci. USA 1998, 95, 1178-1183.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1178-1183
-
-
Staveley-O'Carroll, K.1
Sotomayor, E.2
Montgomery, J.3
Borrello, I.4
Hwang, L.5
Fein, S.6
Pardoll, D.7
Levitsky, H.8
-
96
-
-
84862611102
-
+ T cells that is reversible by pharmacologic intervention
-
+ T cells that is reversible by pharmacologic intervention. J. Immunol. 2012, 188, 5990-6000.
-
(2012)
J. Immunol.
, vol.188
, pp. 5990-6000
-
-
Prinz, P.U.1
Mendler, A.N.2
Masouris, I.3
Durner, L.4
Oberneder, R.5
Noessner, E.6
-
97
-
-
79957621253
-
The insider's guide to leukocyte integrin signalling and function
-
Hogg, N.; Patzak, I.; Willenbrock, F. The insider's guide to leukocyte integrin signalling and function. Nat. Rev. Immunol. 2011, 11, 416-426.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 416-426
-
-
Hogg, N.1
Patzak, I.2
Willenbrock, F.3
-
98
-
-
27544505630
-
The lymphocyte homing receptors: Gatekeepers of the multistep paradigm
-
Sackstein, R. The lymphocyte homing receptors: Gatekeepers of the multistep paradigm. Curr. Opin. Hematol. 2005, 12, 444-450.
-
(2005)
Curr. Opin. Hematol.
, vol.12
, pp. 444-450
-
-
Sackstein, R.1
-
99
-
-
84874426205
-
Diacylglycerol kinase zeta negatively regulates CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow
-
Lee, D.; Kim, J.; Beste, M.T.; Koretzky, G.A.; Hammer, D.A. Diacylglycerol kinase zeta negatively regulates CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow. Integr. Biol. 2012, 4, 606-614.
-
(2012)
Integr. Biol.
, vol.4
, pp. 606-614
-
-
Lee, D.1
Kim, J.2
Beste, M.T.3
Koretzky, G.A.4
Hammer, D.A.5
-
100
-
-
33746214860
-
RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development
-
Priatel, J.J.; Chen, X.; Dhanji, S.; Abraham, N.; Teh, H.-S. RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development. J. Immunol. 2006, 177, 1470-1480.
-
(2006)
J. Immunol.
, vol.177
, pp. 1470-1480
-
-
Priatel, J.J.1
Chen, X.2
Dhanji, S.3
Abraham, N.4
Teh, H.-S.5
-
101
-
-
33845607123
-
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
-
Daniels, M.A.; Teixeiro, E.; Gill, J.; Hausmann, B.; Roubaty, D.; Holmberg, K.; Werlen, G.; Hollander, G.A.; Gascoigne, N.R.J.; Palmer, E. Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling. Nature 2006, 444, 724-729.
-
(2006)
Nature
, vol.444
, pp. 724-729
-
-
Daniels, M.A.1
Teixeiro, E.2
Gill, J.3
Hausmann, B.4
Roubaty, D.5
Holmberg, K.6
Werlen, G.7
Hollander, G.A.8
Gascoigne, N.R.J.9
Palmer, E.10
-
102
-
-
0035500758
-
Duration and strength of extracellular signal-regulated kinase signals are altered during positive versus negative thymocyte selection
-
Mariathasan, S.; Zakarian, A.; Bouchard, D.; Michie, A.M.; Zúñiga-Pflücker, J.C.; Ohashi, P.S. Duration and strength of extracellular signal-regulated kinase signals are altered during positive versus negative thymocyte selection. J. Immunol. 2001, 167, 4966-4973.
-
(2001)
J. Immunol.
, vol.167
, pp. 4966-4973
-
-
Mariathasan, S.1
Zakarian, A.2
Bouchard, D.3
Michie, A.M.4
Zúñiga-Pflücker, J.C.5
Ohashi, P.S.6
-
103
-
-
0034720881
-
A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity
-
Werlen, G.; Hausmann, B.; Palmer, E. A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity. Nature 2000, 406, 422-426.
-
(2000)
Nature
, vol.406
, pp. 422-426
-
-
Werlen, G.1
Hausmann, B.2
Palmer, E.3
-
105
-
-
76249090489
-
I. BioGPS: An extensible and customizable portal for querying and organizing gene annotation resources
-
Wu, C.; Orozco, C.; Boyer, J.; Leglise, M.; Goodale, J.; Batalov, S.; Hodge, C.L.; Haase, J.; Janes, J.; Huss, J.W., III; et al. I. BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol. 2009, 10, R130.
-
(2009)
Genome Biol.
, vol.10
-
-
Wu, C.1
Orozco, C.2
Boyer, J.3
Leglise, M.4
Goodale, J.5
Batalov, S.6
Hodge, C.L.7
Haase, J.8
Janes, J.9
Huss III, J.W.10
-
106
-
-
44249093277
-
Expression analysis of G protein-coupled receptors in mouse macrophages
-
Lattin, J.E.; Schroder, K.; Su, A.I.; Walker, J.R.; Zhang, J.; Wiltshire, T.; Saijo, K.; Glass, C.K.; Hume, D.A.; Kellie, S.; et al. Expression analysis of G protein-coupled receptors in mouse macrophages. Immunome Res 2008, 4, 5.
-
(2008)
Immunome Res
, vol.4
, pp. 5
-
-
Lattin, J.E.1
Schroder, K.2
Su, A.I.3
Walker, J.R.4
Zhang, J.5
Wiltshire, T.6
Saijo, K.7
Glass, C.K.8
Hume, D.A.9
Kellie, S.10
-
107
-
-
11144358198
-
A gene atlas of the mouse and human protein-encoding transcriptomes
-
Su, A.I.; Wiltshire, T.; Batalov, S.; Lapp, H.; Ching, K.A.; Block, D.; Zhang, J.; Soden, R.; Hayakawa, M.; Kreiman, G.; et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl. Acad. Sci. USA 2004, 101, 6062-6067.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6062-6067
-
-
Su, A.I.1
Wiltshire, T.2
Batalov, S.3
Lapp, H.4
Ching, K.A.5
Block, D.6
Zhang, J.7
Soden, R.8
Hayakawa, M.9
Kreiman, G.10
-
108
-
-
84875448568
-
-
University of Pennsylvania, Philadelphia, PA, USA, Unpublished work
-
Joshi, R.P.; Koretzky G.A. Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, USA, Unpublished work, 2013.
-
(2013)
Abramson Family Cancer Research Institute
-
-
Joshi, R.P.1
Koretzky, G.A.2
-
109
-
-
50149083445
-
Synergistic control of T cell development and tumor suppression by diacylglycerol kinase α and ζ
-
Guo, R.; Wan, C.-K.; Carpenter, J.H.; Mousallem, T.; Boustany, R.-M.N.; Kuan, C.-T.; Burks, A.W.; Zhong, X.-P. Synergistic control of T cell development and tumor suppression by diacylglycerol kinase α and ζ. Proc. Natl. Acad. Sci. USA 2008, 105, 11909-11914.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 11909-11914
-
-
Guo, R.1
Wan, C.-K.2
Carpenter, J.H.3
Mousallem, T.4
Boustany, R.-M.N.5
Kuan, C.-T.6
Burks, A.W.7
Zhong, X.-P.8
-
110
-
-
17844375168
-
-
Klinger, M.B.; Guilbault, B.; Goulding, R.E.; Kay, R.J. Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors. 2004, 24, 2695-2704.
-
(2004)
Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors.
, vol.24
, pp. 2695-2704
-
-
Klinger, M.B.1
Guilbault, B.2
Goulding, R.E.3
Kay, R.J.4
-
111
-
-
34247842744
-
The biology of NKT cells
-
Bendelac, A.; Savage, P.B.; Teyton, L. The biology of NKT cells. Annu. Rev. Immunol. 2007, 25, 297-336.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 297-336
-
-
Bendelac, A.1
Savage, P.B.2
Teyton, L.3
-
112
-
-
0028863822
-
Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes
-
Bendelac, A. Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes. J. Exp. Med. 1995, 182, 2091-2096.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 2091-2096
-
-
Bendelac, A.1
-
113
-
-
22944442645
-
Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes
-
Wei, D.G.; Lee, H.; Park, S.-H.; Beaudoin, L.; Teyton, L.; Lehuen, A.; Bendelac, A. Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes. J. Exp. Med. 2005, 202, 239-248.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 239-248
-
-
Wei, D.G.1
Lee, H.2
Park, S.-H.3
Beaudoin, L.4
Teyton, L.5
Lehuen, A.6
Bendelac, A.7
-
114
-
-
20144387328
-
Regulation of NKT cell development by SAP, the protein defective in XLP
-
Nichols, K.E.; Hom, J.; Gong, S.-Y.; Ganguly, A.; Ma, C.S.; Cannons, J.L.; Tangye, S.G.; Schwartzberg, P.L.; Koretzky, G.A.; Stein, P.L. Regulation of NKT cell development by SAP, the protein defective in XLP. Nat. Med. 2005, 11, 340-345.
-
(2005)
Nat. Med.
, vol.11
, pp. 340-345
-
-
Nichols, K.E.1
Hom, J.2
Gong, S.-Y.3
Ganguly, A.4
Ma, C.S.5
Cannons, J.L.6
Tangye, S.G.7
Schwartzberg, P.L.8
Koretzky, G.A.9
Stein, P.L.10
-
115
-
-
15444374149
-
Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product
-
Pasquier, B.; Yin, L.; Fondanèche, M.-C.; Relouzat, F.; Bloch-Queyrat, C.; Lambert, N.; Fischer, A.; de Saint-Basile, G.; Latour, S. Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product. J. Exp. Med. 2005, 201, 695-701.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 695-701
-
-
Pasquier, B.1
Yin, L.2
Fondanèche, M.-C.3
Relouzat, F.4
Bloch-Queyrat, C.5
Lambert, N.6
Fischer, A.7
de Saint-Basile, G.8
Latour, S.9
-
116
-
-
36049012716
-
Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development
-
Griewank, K.; Borowski, C.; Rietdijk, S.; Wang, N.; Julien, A.; Wei, D.G.; Mamchak, A.A.; Terhorst, C.; Bendelac, A. Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 2007, 27, 751-762.
-
(2007)
Immunity
, vol.27
, pp. 751-762
-
-
Griewank, K.1
Borowski, C.2
Rietdijk, S.3
Wang, N.4
Julien, A.5
Wei, D.G.6
Mamchak, A.A.7
Terhorst, C.8
Bendelac, A.9
-
117
-
-
0032853934
-
Cutting edge: NKT cell development is selectively impaired in Fyn-deficient mice
-
Eberl, G.; Lowin-Kropf, B.; MacDonald, H.R. Cutting edge: NKT cell development is selectively impaired in Fyn-deficient mice. J. Immunol. 1999, 163, 4091-4094.
-
(1999)
J. Immunol.
, vol.163
, pp. 4091-4094
-
-
Eberl, G.1
Lowin-Kropf, B.2
McDonald, H.R.3
-
118
-
-
0032723181
-
The Src family tyrosine kinase Fyn regulates natural killer T cell development
-
Gadue, P.; Morton, N.; Stein, P.L. The Src family tyrosine kinase Fyn regulates natural killer T cell development. J. Exp. Med. 1999, 190, 1189-1196.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1189-1196
-
-
Gadue, P.1
Morton, N.2
Stein, P.L.3
-
119
-
-
80052689578
-
Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development
-
Shen, S.; Wu, J.; Srivatsan, S.; Gorentla, B.K.; Shin, J.; Xu, L.; Zhong, X.-P. Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development. J. Immunol. 2011, 187, 2122-2129.
-
(2011)
J. Immunol.
, vol.187
, pp. 2122-2129
-
-
Shen, S.1
Wu, J.2
Srivatsan, S.3
Gorentla, B.K.4
Shin, J.5
Xu, L.6
Zhong, X.-P.7
-
120
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos, M.; Levine, B.L.; Porter, D.L.; Katz, S.; Grupp, S.A.; Bagg, A.; June, C.H. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci. Trans. Med. 2011, 3, 95ra73.
-
(2011)
Sci. Trans. Med.
, vol.3
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
Katz, S.4
Grupp, S.A.5
Bagg, A.6
June, C.H.7
-
121
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter, D.L.; Levine, B.L.; Kalos, M.; Bagg, A.; June, C.H. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N. Engl. J. Med. 2011, 365, 725-733.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
Bagg, A.4
June, C.H.5
-
122
-
-
84862838257
-
Chimeric antigen receptors for T cell immunotherapy: Current understanding and future directions
-
Curran, K.J.; Pegram, H.J.; Brentjens, R.J. Chimeric antigen receptors for T cell immunotherapy: Current understanding and future directions. J. Gene Med. 2012, 14, 405-415.
-
(2012)
J. Gene Med.
, vol.14
, pp. 405-415
-
-
Curran, K.J.1
Pegram, H.J.2
Brentjens, R.J.3
|