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Volumn 2, Issue 66, 2009, Pages

Molecular origin and functional consequences of digital signaling and hysteresis during ras activation in lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAS PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; SOS PROTEIN;

EID: 70349235821     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.266pt2     Document Type: Review
Times cited : (20)

References (11)
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    • G. Altan-Bonnet, R. N. Germain, Modeling T cell antigen discrimination based on feedback control of digital ERK responses. PLoS Biol. 3, e356 (2005).
    • (2005) PLoS Biol. , vol.3
    • Altan-Bonnet, G.1    Germain, R.N.2
  • 3
    • 58249087468 scopus 로고    scopus 로고
    • Origin of digital and analog thresholds discriminating positive and negative selection of T cells in the thymus
    • A. Prasad, J. Das, J. Roose, A. Weiss, A. K. Chakraborty, Origin of digital and analog thresholds discriminating positive and negative selection of T cells in the thymus. Proc. Natl. Acad. Sci. U.S.A. 106, 528-534 (2009).
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 528-534
    • Prasad, A.1    Das, J.2    Roose, J.3    Weiss, A.4    Chakraborty, A.K.5
  • 5
    • 0344885558 scopus 로고    scopus 로고
    • Structural evidence for feedback activation by Ras-GTP of the Ras-specific nucleotide exchange factor SOS
    • S. M. Margarit, H. Sondermann, B. E. Hall, B. Nagar, A. Hoelz, M. Pirruccello, D. Bar-Sagi, J. Kuriyan, Structural evidence for feedback activation by Ras-GTP of the Ras-specific nucleotide exchange factor SOS. Cell 112, 685-695 (2003).
    • (2003) Cell , vol.112 , pp. 685-695
    • Margarit, S.M.1    Sondermann, H.2    Hall, B.E.3    Nagar, B.4    Hoelz, A.5    Pirruccello, M.6    Bar-Sagi, D.7    Kuriyan, J.8
  • 7
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical-reactions
    • D. T. Gillespie, Exact stochastic simulation of coupled chemical-reactions. J. Phys. Chem. 81, 2340-2361 (1977).
    • (1977) J. Phys. Chem. , vol.81 , pp. 2340-2361
    • Gillespie, D.T.1
  • 8
    • 0026711081 scopus 로고
    • Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: The C terminal domain of GAP is not sufficient for full activity
    • P. Gideon, J. John, M. Frech, A. Lautwein, R. Clark, J. E. Sceffler, A. Wittinghoffer, Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: The C terminal domain of GAP is not sufficient for full activity. Mol. Cell. Biol. 12, 2050-2056 (1992).
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2050-2056
    • Gideon, P.1    John, J.2    Frech, M.3    Lautwein, A.4    Clark, R.5    Sceffler, J.E.6    Wittinghoffer, A.7
  • 9
    • 0347593996 scopus 로고    scopus 로고
    • Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-λ 2 to Ras in B cell receptor signaling
    • M. Oh-hora, S. Johmura, A. Hashimoto, M. Hikida, T. Kurosaki, Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-λ 2 to Ras in B cell receptor signaling. J. Exp. Med. 198, 1841-1851 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 1841-1851
    • Oh-hora, M.1    Johmura, S.2    Hashimoto, A.3    Hikida, M.4    Kurosaki, T.5
  • 11
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    • How antigen quantity and quality determine T cell decisions in lymphoid tissues
    • H. Zheng, S. Henrickson, U. von Andrian, A. K. Chakraborty, How antigen quantity and quality determine T cell decisions in lymphoid tissues. Mol. Cell. Biol. 28, 4040-4051 (2008).
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 4040-4051
    • Zheng, H.1    Henrickson, S.2    Von Andrian, U.3    Chakraborty, A.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.