Proteomic allergen-peptide/protein interaction assay for the identification of human skin sensitizers

Toxicology in Vitro

Volumn 27, Issue 3, 2013, Pages 1157-1162

  Dietz, Lisa ^a,c   Kinzebach, Sven ^a,b   Ohnesorge, Stefanie ^a   Franke, Bastian ^a   Goette, Irina ^a   Koenig Gressel, Dieter ^a   Thierse, Hermann Josef ^a,c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MEDICAL FACULTY MANNHEIM HEIDELBERG UNIVERSITY   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Adduct formation; Chemical peptide interaction; Hapten; In vitro systems; Mass spectrometry; Skin sensitization; Small reactive chemicals

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALLERGEN; CINNAMALDEHYDE; CYSTEINE; IRRITANT AGENT; PEPTIDE; SALICYLIC ACID;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; FREEZING; IN VITRO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; OXIDATION; PH; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SKIN SENSITIZATION; SKIN SURFACE; STRUCTURE ANALYSIS;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; BIOLOGICAL ASSAY; HUMANS; PEPTIDES; PROTEINS; SKIN IRRITANCY TESTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

ANIMALIA;

EID: 84875380096     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.08.013     Document Type: Article

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