Mass spectrometric identification of covalent adducts of the skin allergen 2,4-dinitro-1-chlorobenzene and model skin proteins

Toxicology in Vitro

Volumn 22, Issue 5, 2008, Pages 1169-1176

  Aleksic, Maja ^a   Pease, Camilla K ^b   Basketter, David A ^b   Panico, Maria ^a   Morris, Howard R ^a,c   Dell, Anne ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNILEVER RESEARCH   (United Kingdom)

^c M SCAN Ltd   (United Kingdom)

Author keywords

Hapten; Human cofilin; Human keratin 14; In vitro; Mass spectrometry; Protein adducts; Skin sensitisation

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALLERGEN; AMINO ACID; BENZALKONIUM CHLORIDE; COFILIN; CYTOKERATIN; CYTOKERATIN 14; HAPTEN; PEPTIDE;

ARTICLE; BINDING ASSAY; COVALENT BOND; HUMAN; HUMAN CELL; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROENVIRONMENT; NANOTECHNOLOGY; PROTEIN STRUCTURE;

ACTIN DEPOLYMERIZING FACTORS; ALLERGENS; BENZALKONIUM COMPOUNDS; DINITROCHLOROBENZENE; HAPTENS; HUMANS; KERATIN-14; NANOTECHNOLOGY; NITROBENZENES; PEPTIDE MAPPING; RECOMBINANT PROTEINS; SKIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 46549088893     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2008.03.006     Document Type: Article

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