T cell receptor (TCR) interaction with haptens: Metal ions as non-classical haptens

Toxicology

Volumn 209, Issue 2, 2005, Pages 101-107

  Thierse, Hermann Josef ^a,b   Gamerdinger, Katharina ^a   Junkes, Christof ^a   Guerreiro, Nelson ^c   Weltzien, Hans Ulrich ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Albumin; Heat shock; Hypersensitivity; Nickel; Protein; T lymphocyte

Indexed keywords

CHAPERONE; HAPTEN; HEAT SHOCK PROTEIN; HUMAN SERUM ALBUMIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; METAL ION; NICKEL COMPLEX; T LYMPHOCYTE RECEPTOR; TRANSFERRIN;

B LYMPHOCYTE; CELL LINE; CHEMICAL BINDING; CONFERENCE PAPER; CONTACT ALLERGY; CONTROLLED STUDY; CROSS LINKING; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR HISTOCOMPATIBILITY COMPLEX; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN INTERACTION; T LYMPHOCYTE;

EID: 17644404780     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.12.015     Document Type: Conference Paper

References (30)

1. L. Budinger, and M. Hertl Immunologic mechanisms in hypersensitivity reactions to metal ions: an overview Allergy 55 2000 108 115
2. L. Budinger, N. Neuser, U. Totzke, H.F. Merk, and M. Hertl Preferential usage of TCR-Vbeta17 by peripheral and cutaneous T cells in nickel-induced contact dermatitis J. Immunol. 167 2001 6038 6044
3. S. Buus, A. Sette, S.M. Colon, C. Miles, and H.M. Grey The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides Science 235 1987 1353 1358
4. S. Carroll, and E.J. Wood Exposure of human keratinocytes and fibroblasts in vitro to nickel sulphate ions induces synthesis of stress proteins Hsp72 and Hsp90 [In Process Citation] Acta Derm. Venereol. 80 2000 94 97
5. B. Ernst, D.S. Lee, J.M. Chang, J. Sprent, and C.D. Surh The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery Immunity 11 1999 173 181
6. J.J.R. Fausto da Silva, and R.J.P. Williams The biological chemistry of the elements. The inorganic chemistry of life 2nd ed. 2001 Oxford University Press Oxford, UK
7. K. Gamerdinger, C. Moulon, D.R. Karp, J. Van Bergen, F. Koning, D. Wild, U. Pflugfelder, and H.U. Weltzien A new type of metal recognition by human T cells: contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel J. Exp. Med. 197 2003 1345 1353
8. P. Griem, C. Vonvultee, K. Panthel, S.L. Best, P.J. Sadler, and C.F. Shaw T-cell cross-reactivity to heavy-metals - identical cryptic peptides may be presented from protein exposed to different metals Eur. J. Immunol. 28 1998 1941 1947
9. C. Hannum, J.H. Freed, G. Tarr, J. Kappler, and P. Marrack Biochemistry and distribution of the T cell receptor Immunol. Rev. 81 1984 161 176
10. Heiss, K., Junkes, C., Guerreiro, N., Swamy, M., Camacho-Carvajal, M.M., Schamel, W.W.A., Haidl, I.D., Wild, D., Weltzien, H.U., Thierse, H.-J., 2005. Subproteomic analysis of metal-interacting proteins in human B cells. Proteomics, in press.
11. H. Jonuleit, U. Kuhn, G. Muller, K. Steinbrink, L. Paragnik, E. Schmitt, J. Knop, and A.H. Enk Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions Eur. J. Immunol. 27 1997 3135 3142
12. P. Jungblut, H. Baumeister, and J. Klose Classification of mouse liver proteins by immobilized metal affinity chromatography and two-dimensional electrophoresis Electrophoresis 14 1993 638 643
13. R.S. Kalish, J.A. Wood, and A. LaPorte Processing of urushiol (poison ivy) hapten by both endogenous and exogenous pathways for presentation to T cells in vitro J. Clin. Invest. 93 1994 2039 2047
14. K. Landsteiner, and J.L. Jacobs Studies on the sensitization of animals with simple chemical compounds J. Exp. Med. 61 1935 643
15. L. Lu, J. Vollmer, C. Moulon, H.U. Weltzien, P. Marrack, and J. Kappler Components of the ligand for a Ni++ reactive human T cell clone J. Exp. Med. 197 2003 567 574
16. T. Menne Prevention of nickel allergy by regulation of specific exposures Ann. Clin. Lab. Sci. 26 1996 133 138
17. C. Moulon, J. Vollmer, and H.U. Weltzien Characterization of processing requirements and metal cross-reactivities in T cell clones from patients with allergic contact dermatitis to nickel Eur. J. Immunol. 25 1995 3308 3315
18. F.O. Nestle, H. Speidel, and M.O. Speidel Metallurgy: high nickel release from 1- and 2-euro coins Nature 419 2002 132
19. N.H. Nielsen, A. Linneberg, T. Menne, F. Madsen, L. Frolund, A. Dirksen, and T. Jorgensen Incidence of allergic contact sensitization in Danish adults between 1990 and 1998; the Copenhagen Allergy Study, Denmark Br. J. Dermatol. 147 2002 487 492
20. B. Ortmann, S. Martin, A. von Bonin, E. Schiltz, H. Hoschutzky, and H.U. Weltzien Synthetic peptides anchor T cell-specific TNP epitopes to MHC antigens J. Immunol. 148 1992 1445 1450
21. H. Pohlit, W. Haas, and H. von Boehmer Cytotoxic T cell responses to haptenated cells. I. Primary, secondary and long-term cultures Eur. J. Immunol. 9 1979 681 690
22. G.M. Shearer Cell-mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes Eur. J. Immunol. 4 1974 527 533
23. F. Sinigaglia The molecular basis of metal recognition by T cells J. Invest. Dermatol. 102 1994 398 401 [published erratum appears in J. Invest. Dermatol. 1994; 103:41]
24. H.J. Thierse, C. Moulon, Y. Allespach, B. Zimmermann, A. Doetze, S. Kuppig, D. Wild, F. Herberg, and H.U. Weltzien Metal-protein complex-mediated transport and delivery of Ni2+ to TCR/MHC contact sites in nickel-specific human T cell activation J. Immunol. 172 2004 1926 1934
25. J. Vollmer, M. Fritz, A. Dormoy, H.U. Weltzien, and C. Moulon Dominance of the BV17 element in nickel-specific human T cell receptors relates to severity of contact sensitivity Eur. J. Immunol. 27 1997 1865 1874
26. J. Vollmer, H.U. Weltzien, and C. Moulon TCR reactivity in human nickel allergy indicates contacts with complementarity-determining region 3 but excludes superantigen-like recognition J. Immunol. 163 1999 2723 2731
27. Weltzien, H.U., Dötze, A., Gamerdinger, K., Hellwig, S., Thierse, H.-J., 2004. Molecular recognition of haptens by T cells: more than one way to tickle the receptor. In: A. Cavani, G. Girolomoni (Eds.), Immune Mechanisms in Allergic Contact Dermatitis. Landes Bioscience, Georgetown, TX, USA, pp. 14-27. Online access: www.Eurekah.com.
28. H.U. Weltzien, C. Moulon, S. Martin, E. Padovan, U. Hartmann, and J. Kohler T cell immune responses to haptens. Structural models for allergic and autoimmune reactions Toxicology 107 1996 141 151
29. H.U. Weltzien, and E. Padovan Molecular features of penicillin allergy J. Invest. Dermatol. 110 1998 203 206
30. Y. Zhang, and D.E. Wilcox Thermodynamic and spectroscopic study of Cu(II) and Ni(II) binding to bovine serum albumin J. Biol. Inorg. Chem. 7 2002 327 337