메뉴 건너뛰기




Volumn 12, Issue 1, 2013, Pages 55-61

Palmitoylethanolamide in homeostatic and traumatic central nervous system injuries

Author keywords

Glial cells; N acylethanolamine; Neuroprotection; Spinal cord

Indexed keywords

CANNABINOID 2 RECEPTOR; PALMIDROL;

EID: 84875338025     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527311312010010     Document Type: Review
Times cited : (78)

References (94)
  • 1
    • 84875299926 scopus 로고    scopus 로고
    • Enna, S.J.; Bylund D.B. "xPharm: The Comprehensive Pharmacology Reference, Elsevier
    • S.P.H. N-Palmitoylethanolamine. In: Enna, S.J.; Bylund D.B. xPharm: The Comprehensive Pharmacology Reference". 2009, Elsevier, pp. 1-4
    • (2009) N-Palmitoylethanolamine , pp. 1-4
  • 2
    • 77953291080 scopus 로고    scopus 로고
    • N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities
    • Petrosino, S.; Iuvone, T.; Di Marzo, V. N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities. Biochimie., 2010, 92(6), 724-727.
    • (2010) Biochimie , vol.92 , Issue.6 , pp. 724-727
    • Petrosino, S.1    Iuvone, T.2    Di Marzo, V.3
  • 3
    • 33846378110 scopus 로고    scopus 로고
    • Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: Potential use in companion animals
    • Re, G.; Barbero, R.; Miolo, A.; Di Marzo, V. Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: Potential use in companion animals. Vet J., 2007, 173(1), 21-30.
    • (2007) Vet J , vol.173 , Issue.1 , pp. 21-30
    • Re, G.1    Barbero, R.2    Miolo, A.3    Di Marzo, V.4
  • 4
    • 3242703446 scopus 로고    scopus 로고
    • Occurrence, metabolism, and prospective functions of N-acylethanolamines in plants
    • Chapman, K.D. Occurrence, metabolism, and prospective functions of N-acylethanolamines in plants. Prog Lipid Res., 2004, 43(4), 302-327.
    • (2004) Prog Lipid Res , vol.43 , Issue.4 , pp. 302-327
    • Chapman, K.D.1
  • 5
    • 84891727054 scopus 로고    scopus 로고
    • Anandamide and Other Acylethanolamides. Chapter 5 In: Tettamanti G and Goracci G (eds.), Handbook of neurochemistry and molecular neurobiology. Neural Lipids, 3rd edition
    • Petrosino, S.; Di Marzo, V. Anandamide and Other Acylethanolamides. Chapter 5 In: Tettamanti G and Goracci G (eds.), Handbook of neurochemistry and molecular neurobiology. Neural Lipids, 3rd edition, Springer, 2009, pp.75-98.
    • Springer , vol.2009 , pp. 75-98
    • Petrosino, S.1    Di Marzo, V.2
  • 6
    • 0031031557 scopus 로고    scopus 로고
    • Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes
    • Bisogno, T.; Maurelli, S.; Melck, D.; De Petrocellis, L.; Di Marzo, V. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. J. Biol. Chem., 1997, 272(6), 3315-3323.
    • (1997) J. Biol. Chem , vol.272 , Issue.6 , pp. 3315-3323
    • Bisogno, T.1    Maurelli, S.2    Melck, D.3    de Petrocellis, L.4    Di Marzo, V.5
  • 7
    • 0035043018 scopus 로고    scopus 로고
    • Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: Comparison with anandamide
    • Jacobsson, S.O.; Fowler, C.J. Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. Br. J. Pharmacol. 2001, 132(8), 1743-1754.
    • (2001) Br. J. Pharmacol , vol.132 , Issue.8 , pp. 1743-1754
    • Jacobsson, S.O.1    Fowler, C.J.2
  • 8
    • 0000434849 scopus 로고
    • The effect of egg yolk in diets on anaphylactic arthritis (passive Arthus phenomenon) in the guinea pig
    • Coburn, A.F.; Graham, C.E.; Haninger, J. The effect of egg yolk in diets on anaphylactic arthritis (passive Arthus phenomenon) in the guinea pig. J. Exp. Med., 1954, 100(5), 425-435.
    • (1954) J. Exp. Med , vol.100 , Issue.5 , pp. 425-435
    • Coburn, A.F.1    Graham, C.E.2    Haninger, J.3
  • 9
    • 0000947743 scopus 로고
    • Factor in arachis oil depressing sensitivity to tuberculin in B.C.G.-infected guineapigs
    • Long, D.A.; Martin, A.J. Factor in arachis oil depressing sensitivity to tuberculin in B.C.G.-infected guineapigs. Lancet., 1956, 270(6921), 464-466.
    • (1956) Lancet , vol.270 , Issue.6921 , pp. 464-466
    • Long, D.A.1    Martin, A.J.2
  • 10
    • 0001162640 scopus 로고
    • The identification of N-(2-hydroxyethyl)-palmitamide as a naturally occuring anti-inflammatory agent
    • Kuehl, F.A.; Jacob, T.A.; Ganley, O.H.; Ormond, R.E.; Meisinger, M.A.P. The identification of N-(2-hydroxyethyl)-palmitamide as a naturally occuring anti-inflammatory agent. J. Am. Chem. Soc., 1957, 79(19), 5577-5578.
    • (1957) J. Am. Chem. Soc , vol.79 , Issue.19 , pp. 5577-5578
    • Kuehl, F.A.1    Jacob, T.A.2    Ganley, O.H.3    Ormond, R.E.4    Meisinger, M.A.P.5
  • 11
    • 0011433814 scopus 로고
    • Anti-inflammatory activity on compounds obtained from egg yolk, peanut oil, and soybean lecithin
    • Ganley, O.H.; Graessle, O.E.; Robinson, H.J. Anti-inflammatory activity on compounds obtained from egg yolk, peanut oil, and soybean lecithin. J. Lab. Clin. Med., 1958, 51(5),709-714.
    • (1958) J. Lab. Clin. Med , vol.51 , Issue.5 , pp. 709-714
    • Ganley, O.H.1    Graessle, O.E.2    Robinson, H.J.3
  • 12
    • 0014416308 scopus 로고
    • Activity of some derivatives of palmitoylethanolamide on carragenine-induced edema in the rat paw
    • Benvenuti, F.; Lattanzi, F.; De Gori, A.; Tarli, P. Activity of some derivatives of palmitoylethanolamide on carragenine-induced edema in the rat paw. Boll. Soc. Ital. Biol. Sper., 1968, 44(9), 809-813.
    • (1968) Boll. Soc. Ital. Biol. Sper , vol.44 , Issue.9 , pp. 809-813
    • Benvenuti, F.1    Lattanzi, F.2    de Gori, A.3    Tarli, P.4
  • 13
    • 0015186245 scopus 로고
    • Anti-inflammatory properties of N(2-hydroxyethyl) palmitamide
    • Perlik, F.; Raskova, H.; Elis, J. Anti-inflammatory properties of N(2-hydroxyethyl) palmitamide. Acta Physiol. Acad. Sci. Hung., 1971, 39(4), 395-400.
    • (1971) Acta Physiol. Acad. Sci. Hung , vol.39 , Issue.4 , pp. 395-400
    • Perlik, F.1    Raskova, H.2    Elis, J.3
  • 14
    • 0027313392 scopus 로고
    • A proposed autacoid mechanism controlling mastocyte behaviour
    • Aloe, L.; Leon, A.; Levi-Montalcini, R. A proposed autacoid mechanism controlling mastocyte behaviour. Agents Actions., 1993, 3 (C), 145-147.
    • (1993) Agents Actions , vol.3 , Issue.C , pp. 145-147
    • Aloe, L.1    Leon, A.2    Levi-Montalcini, R.3
  • 15
    • 45749155263 scopus 로고    scopus 로고
    • Nerve-mast cell and smooth muscle-mast cell interaction mediated by cell adhesion molecule-1, CADM1
    • Ito, A.; Hagiyama, M.; Oonuma, J. Nerve-mast cell and smooth muscle-mast cell interaction mediated by cell adhesion molecule-1, CADM1. J. Smooth Muscle. Res., 2008, 44(2), 83-93.
    • (2008) J. Smooth Muscle. Res , vol.44 , Issue.2 , pp. 83-93
    • Ito, A.1    Hagiyama, M.2    Oonuma, J.3
  • 16
    • 77952868792 scopus 로고    scopus 로고
    • Mast cell-orchestrated immunity to pathogens
    • Abraham, S.N.; St John, AL. Mast cell-orchestrated immunity to pathogens. Nat. Rev. Immunol., 2010, 10(6), 440-452.
    • (2010) Nat. Rev. Immunol , vol.10 , Issue.6 , pp. 440-452
    • Abraham, S.N.1    St John, A.L.2
  • 17
    • 36849072350 scopus 로고    scopus 로고
    • The mast cell and allergic diseases: Role in pathogenesis and implications for therapy
    • Brown, J.M.; Wilson, T.M.; Metcalfe, D.D. The mast cell and allergic diseases: role in pathogenesis and implications for therapy. Clin. Exp. Allergy., 2008, 38(1), 4-18.
    • (2008) Clin. Exp. Allergy , vol.38 , Issue.1 , pp. 4-18
    • Brown, J.M.1    Wilson, T.M.2    Metcalfe, D.D.3
  • 18
    • 78649518547 scopus 로고    scopus 로고
    • Mast cells: Emerging sentinel innate immune cells with diverse role in immunity
    • Kumar, V.; Sharma, A. Mast cells: Emerging sentinel innate immune cells with diverse role in immunity. Mol. Immunol., 2010, 48(1-3), 14-25.
    • (2010) Mol. Immunol , vol.48 , Issue.1-3 , pp. 14-25
    • Kumar, V.1    Sharma, A.2
  • 22
    • 79953713651 scopus 로고    scopus 로고
    • Biological implications of preformed mast cell mediators
    • Lundequist, A.; Pejler, G. Biological implications of preformed mast cell mediators. Cell. Mol. Life Sci., 2011, 68(6), 965-975.
    • (2011) Cell. Mol. Life Sci , vol.68 , Issue.6 , pp. 965-975
    • Lundequist, A.1    Pejler, G.2
  • 23
    • 70349279924 scopus 로고    scopus 로고
    • Physiological and pathophysiological functions of intestinal mast cells
    • Bischoff, S.C. Physiological and pathophysiological functions of intestinal mast cells. Semin. Immunopathol., 2009, 31(2), 185-205.
    • (2009) Semin. Immunopathol , vol.31 , Issue.2 , pp. 185-205
    • Bischoff, S.C.1
  • 24
    • 34248186535 scopus 로고    scopus 로고
    • Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti-rheumatic therapy
    • Eklund, K.K. Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti-rheumatic therapy. Immunol Rev., 2007, 217, 38-52.
    • (2007) Immunol Rev , vol.217 , pp. 38-52
    • Eklund, K.K.1
  • 26
    • 57149091790 scopus 로고    scopus 로고
    • Role of Mast Cells in Progressive Renal Diseases
    • Holdsworth, S.R.; Summers, S.A. Role of Mast Cells in Progressive Renal Diseases. J. Am. Soc. Nephrol., 2008, 19(12), 2254-2261.
    • (2008) J. Am. Soc. Nephrol , vol.19 , Issue.12 , pp. 2254-2261
    • Holdsworth, S.R.1    Summers, S.A.2
  • 27
    • 56649085176 scopus 로고    scopus 로고
    • Brain mast cells link the immune system to anxiety-like behavior
    • Nautiyal, K.M.; Ribeiro, A.C.; Pfaff, D.W.; Silver, R. Brain mast cells link the immune system to anxiety-like behavior. Proc. Natl. Acad. Sci. U S A., 2008, 105(46), 18053-18057.
    • (2008) Proc. Natl. Acad. Sci. U S A , vol.105 , Issue.46 , pp. 18053-18057
    • Nautiyal, K.M.1    Ribeiro, A.C.2    Pfaff, D.W.3    Silver, R.4
  • 29
    • 0028906566 scopus 로고
    • Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide
    • Facci, L.; Dal Toso, R.; Romanello, S.; Buriani, A.; Skaper, S.D.; Leon, A. Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. Proc. Natl. Acad. Sci., 1995, 92(8), 3376-3380.
    • (1995) Proc. Natl. Acad. Sci , vol.92 , Issue.8 , pp. 3376-3380
    • Facci, L.1    Dal Toso, R.2    Romanello, S.3    Buriani, A.4    Skaper, S.D.5    Leon, A.6
  • 30
    • 0036216311 scopus 로고    scopus 로고
    • The palmitoylethanolamide family: A new class of anti-inflammatory agents?
    • Lambert, D.M.; Vandevoorde, S.; Jonsson, K.O.; Fowler, C.J. The palmitoylethanolamide family: a new class of anti-inflammatory agents? Curr. Med. Chem., 2002, 9(6), 663-674.
    • (2002) Curr. Med. Chem , vol.9 , Issue.6 , pp. 663-674
    • Lambert, D.M.1    Vandevoorde, S.2    Jonsson, K.O.3    Fowler, C.J.4
  • 31
    • 0032766027 scopus 로고    scopus 로고
    • The palmitoylethanolamide and oleamide enigmas: Are these two fatty acid amides cannabimimetic?
    • Lambert, D.M.; Di Marzo, V. The palmitoylethanolamide and oleamide enigmas: are these two fatty acid amides cannabimimetic? Curr. Med. Chem., 1999, 6(8), 757-773.
    • (1999) Curr. Med. Chem , vol.6 , Issue.8 , pp. 757-773
    • Lambert, D.M.1    Di Marzo, V.2
  • 32
    • 0030425575 scopus 로고    scopus 로고
    • Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
    • Showalter, V.M.; Compton, D.R.; Martin, B.R.; Abood, M.E. Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. J. Pharmacol. Exp. Ther., 1996, 278(3), 989-999.
    • (1996) J. Pharmacol. Exp. Ther , vol.278 , Issue.3 , pp. 989-999
    • Showalter, V.M.1    Compton, D.R.2    Martin, B.R.3    Abood, M.E.4
  • 33
    • 0034614374 scopus 로고    scopus 로고
    • Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells
    • Sugiura, T.; Kondo, S.; Kishimoto, S.; Miyashita, T.; Nakane, S.; Kodaka, T.; Suhara, Y.; Takayama, H.; Waku, K. Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. J. Biol. Chem., 2000, 275(1), 605-612.
    • (2000) J. Biol. Chem , vol.275 , Issue.1 , pp. 605-612
    • Sugiura, T.1    Kondo, S.2    Kishimoto, S.3    Miyashita, T.4    Nakane, S.5    Kodaka, T.6    Suhara, Y.7    Takayama, H.8    Waku, K.9
  • 34
    • 0031776783 scopus 로고    scopus 로고
    • The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain
    • Jaggar, S.I.; Hasnie, F.S.; Sellaturay, S.; Rice, A.S. The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. Pain., 1998, 76(1-2), 189-199.
    • (1998) Pain , vol.76 , Issue.1-2 , pp. 189-199
    • Jaggar, S.I.1    Hasnie, F.S.2    Sellaturay, S.3    Rice, A.S.4
  • 35
    • 0032537734 scopus 로고    scopus 로고
    • Control of pain initiation by endogenous cannabinoids
    • Calignano, A.; La Rana, G.; Giuffrida, A.; Piomelli, D. Control of pain initiation by endogenous cannabinoids. Nature, 1998, 394(6690), 277-281.
    • (1998) Nature , vol.394 , Issue.6690 , pp. 277-281
    • Calignano, A.1    la Rana, G.2    Giuffrida, A.3    Piomelli, D.4
  • 36
    • 0036157693 scopus 로고    scopus 로고
    • Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat
    • Conti, S.; Costa, B.; Colleoni, M.; Parolaro, D.; Giagnoni, G. Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat. Br. J. Pharmacol., 2002, 135(1),181-187.
    • (2002) Br. J. Pharmacol , vol.135 , Issue.1 , pp. 181-187
    • Conti, S.1    Costa, B.2    Colleoni, M.3    Parolaro, D.4    Giagnoni, G.5
  • 38
    • 77950630872 scopus 로고    scopus 로고
    • GPR55: Current Knowledge and Future Perspectives of a Purported Type-3 Cannabinoid Receptor
    • Moriconi, A.; Cerbara, I.; Maccarrone, M.; Topai, A. GPR55: Current Knowledge and Future Perspectives of a Purported Type-3 Cannabinoid Receptor. Curr. Med. Chem., 2010, 17(14), 1411-1429.
    • (2010) Curr. Med. Chem , vol.17 , Issue.14 , pp. 1411-1429
    • Moriconi, A.1    Cerbara, I.2    Maccarrone, M.3    Topai, A.4
  • 39
    • 11244328917 scopus 로고    scopus 로고
    • The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide
    • LoVerme, J.; Fu, J.; Astarita, G.; La Rana, G.; Russo, R.; Calignano, A.; Piomelli, D. The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide. Mol. Pharmacol.,2005, 67(1), 15-19.
    • (2005) Mol. Pharmacol , vol.67 , Issue.1 , pp. 15-19
    • Loverme, J.1    Fu, J.2    Astarita, G.3    la Rana, G.4    Russo, R.5    Calignano, A.6    Piomelli, D.7
  • 40
    • 77954175115 scopus 로고    scopus 로고
    • Cannabinoid activation of peroxisome proliferator-activated receptors: Potential for modulation of inflammatory disease
    • O'Sullivan, S.E.; Kendall, D.A. Cannabinoid activation of peroxisome proliferator-activated receptors: Potential for modulation of inflammatory disease. Immunobiology, 2010, 215(8), 611-616.
    • (2010) Immunobiology , vol.215 , Issue.8 , pp. 611-616
    • O'Sullivan, S.E.1    Kendall, D.A.2
  • 44
    • 0028837562 scopus 로고
    • Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain
    • Schmid, P.C.; Krebsbach, R.J.; Perry, S.R.; Dettmer, T.M.; Maasson, J.L.; Schmid, H.H. Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain. FEBS Lett., 1995, 375(1-2), 117-120.
    • (1995) FEBS Lett , vol.375 , Issue.1-2 , pp. 117-120
    • Schmid, P.C.1    Krebsbach, R.J.2    Perry, S.R.3    Dettmer, T.M.4    Maasson, J.L.5    Schmid, H.H.6
  • 48
    • 33749996485 scopus 로고    scopus 로고
    • Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: A role for endogenous fatty-acid ethanolamides?
    • Guindon, J.; LoVerme, J.; De Lean, A.; Piomelli, D.; Beaulieu, P. Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: A role for endogenous fatty-acid ethanolamides? Eur. J. Pharmacol., 2006, 550(1-3), 68-77.
    • (2006) Eur. J. Pharmacol , vol.550 , Issue.1-3 , pp. 68-77
    • Guindon, J.1    Loverme, J.2    de Lean, A.3    Piomelli, D.4    Beaulieu, P.5
  • 50
    • 33750452664 scopus 로고    scopus 로고
    • Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration
    • Matias, I.; Wang, J.W.; Moriello, A.S.; Nieves, A.; Woodward, D.F.; Di Marzo, V. Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. Prostaglandins Leukot. Essent. Fatty Acids., 2006, 75(6), 413-418.
    • (2006) Prostaglandins Leukot. Essent. Fatty Acids , vol.75 , Issue.6 , pp. 413-418
    • Matias, I.1    Wang, J.W.2    Moriello, A.S.3    Nieves, A.4    Woodward, D.F.5    Di Marzo, V.6
  • 53
    • 70349089224 scopus 로고    scopus 로고
    • Simultaneous quantitative analysis of n-acylethanolamides in clinical samples
    • Ozalp, A.; Barroso, B. Simultaneous quantitative analysis of n-acylethanolamides in clinical samples. Anal. Biochem., 2009, 395(1), 68-76.
    • (2009) Anal. Biochem , vol.395 , Issue.1 , pp. 68-76
    • Ozalp, A.1    Barroso, B.2
  • 54
    • 65249103959 scopus 로고    scopus 로고
    • Development and validation of a quantitative method for the determination of 12 endocannabinoids and related compounds in human plasma using liquid chromatography-tandem mass spectrometry
    • Balvers, M.G.J.; Verhoeckx, K.C.M.; Witkamp, R.F. Development and validation of a quantitative method for the determination of 12 endocannabinoids and related compounds in human plasma using liquid chromatography-tandem mass spectrometry. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci., 2009, 877(14-15), 1583-1590.
    • (2009) J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci , vol.877 , Issue.14-15 , pp. 1583-1590
    • Balvers, M.G.J.1    Verhoeckx, K.C.M.2    Witkamp, R.F.3
  • 55
    • 79952299578 scopus 로고    scopus 로고
    • Central and peripheral endocannabinoids and cognate acylethanolamides in humans: Association with race, adiposity, and energy expenditure
    • Jumpertz, R.; Guijarro, A.; Pratley, R.E.; Piomelli, D.; Krakoff, J. Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. J. Clin. Endocrinol. Metab., 2011, 96(3), 787-91.
    • (2011) J. Clin. Endocrinol. Metab , vol.96 , Issue.3 , pp. 787-791
    • Jumpertz, R.1    Guijarro, A.2    Pratley, R.E.3    Piomelli, D.4    Krakoff, J.5
  • 56
    • 0032488797 scopus 로고    scopus 로고
    • Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma
    • Giuffrida, A.; Piomelli, D. Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma. FEBS Lett., 1998, 422(3), 373-376.
    • (1998) FEBS Lett , vol.422 , Issue.3 , pp. 373-376
    • Giuffrida, A.1    Piomelli, D.2
  • 58
    • 84875281625 scopus 로고    scopus 로고
    • Increased skin levels of the aliamide palmitoylethanolamide and other endogenous fatty acid amides in dogs with atopic dermatitis. 33rd Annual WSAVA/FECAVA Congress, Dublin
    • August
    • Petrosino, S.; Albanese, F.; Abramo, F.; Di Marzo, V. Increased skin levels of the aliamide palmitoylethanolamide and other endogenous fatty acid amides in dogs with atopic dermatitis. 33rd Annual WSAVA/FECAVA Congress, Dublin, Ireland, 20th-24th August 2008, p. 707.
    • (2008) Ireland, 20th-24th , pp. 707
    • Petrosino, S.1    Albanese, F.2    Abramo, F.3    Di Marzo, V.4
  • 59
    • 84859239736 scopus 로고    scopus 로고
    • High levels of N-palmitoylethanolamide and N-stearoylethanolamide in microdialysate samples from myalgic trapezius muscle in women
    • Ghafouri, N; Ghafouri, B; Larsson, B; Turkina, MV.; Karlsson, L.; Fowler, CJ.; Gerdle, B. High levels of N-palmitoylethanolamide and N-stearoylethanolamide in microdialysate samples from myalgic trapezius muscle in women. PLoS One., 2011, 6(11), e27257.
    • (2011) PLoS One , vol.6 , Issue.11
    • Ghafouri, N.1    Ghafouri, B.2    Larsson, B.3    Turkina, M.V.4    Karlsson, L.5    Fowler, C.J.6    Gerdle, B.7
  • 60
    • 0033665923 scopus 로고    scopus 로고
    • Emerging physiological roles for N-acylphosphatidylethanolamine metabolism in plants: Signal transduction and membrane protection
    • K.D. Emerging physiological roles for N-acylphosphatidylethanolamine metabolism in plants: signal transduction and membrane protection. Chem. Phys. Lipids., 2000, 108(1-2), 221-230.
    • (2000) Chem. Phys. Lipids , vol.108 , Issue.1-2 , pp. 221-230
  • 61
    • 71649099454 scopus 로고    scopus 로고
    • Effects of palmitoylethanolamide on immunologically induced histamine, PGD2 and TNFa release from canine skin mast cells
    • Cerrato, S.; Brazis, P.; Miolo, A.; della Valle, MF.; Puigdemont, A. Effects of palmitoylethanolamide on immunologically induced histamine, PGD2 and TNFa release from canine skin mast cells. Vet. Immunol. Immunopathol, 2010, 133(1), 9-15.
    • (2010) Vet. Immunol. Immunopathol , vol.133 , Issue.1 , pp. 9-15
    • Cerrato, S.1    Brazis, P.2    Miolo, A.3    della Valle, M.F.4    Puigdemont, A.5
  • 63
    • 0029870716 scopus 로고    scopus 로고
    • The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons
    • Skaper, S.D.; Buriani, A.; Dal Toso, R; Petrelli, L.; Romanello, S.; Facci, L.; Leon, A. The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. Proc. Natl. Acad. Sci. U S A., 1996, 93(9), 3984-3989.
    • (1996) Proc. Natl. Acad. Sci. U S A , vol.93 , Issue.9 , pp. 3984-3989
    • Skaper, S.D.1    Buriani, A.2    Dal Toso, R.3    Petrelli, L.4    Romanello, S.5    Facci, L.6    Leon, A.7
  • 64
    • 0036797445 scopus 로고    scopus 로고
    • Therapeutic effect of the endogenous fatty acid amide, palmitoylethanolamide, in rat acute inflammation: Inhibition of nitric oxide and cyclo-oxygenase systems
    • Costa, B.; Conti, S.; Giagnoni, G.; Colleoni, M. Therapeutic effect of the endogenous fatty acid amide, palmitoylethanolamide, in rat acute inflammation: inhibition of nitric oxide and cyclo-oxygenase systems. Br. J. Pharmacol, 2002, 137(4), 413-420.
    • (2002) Br. J. Pharmacol , vol.137 , Issue.4 , pp. 413-420
    • Costa, B.1    Conti, S.2    Giagnoni, G.3    Colleoni, M.4
  • 66
    • 77953103422 scopus 로고    scopus 로고
    • La palmitoiletanolamida (Normast®) en el dolor neuropático crónico por lumbociatalgia de tipo compresivo: Estudio clínico multicéntrico
    • Guida, G.; de Martino, M.; de Fabiani, A.; Cantieri, L.; Alexandre, A.; Vassallo, G.M.; Rogai, M.; Lanaia, F.; Petrosino, S. La palmitoiletanolamida (Normast®) en el dolor neuropático crónico por lumbociatalgia de tipo compresivo: estudio clínico multicéntrico. Dolor., 2010, 25, 35-42.
    • (2010) Dolor , vol.25 , pp. 35-42
    • Guida, G.1    de Martino, M.2    de Fabiani, A.3    Cantieri, L.4    Alexandre, A.5    Vassallo, G.M.6    Rogai, M.7    Lanaia, F.8    Petrosino, S.9
  • 67
    • 79957659495 scopus 로고    scopus 로고
    • Use of the palmitoylethanolamide in the entrapment neuropathy of the median in the wrist
    • Conigliaro, R.; Drago, V.; Foster, P.S.; Schievano, C; Di Marzo, V. Use of the palmitoylethanolamide in the entrapment neuropathy of the median in the wrist. Minerva Med., 2011, 102(2), 141-147.
    • (2011) Minerva Med , vol.102 , Issue.2 , pp. 141-147
    • Conigliaro, R.1    Drago, V.2    Foster, P.S.3    Schievano, C.4    Di Marzo, V.5
  • 68
    • 37749016059 scopus 로고    scopus 로고
    • Adjuvant treatment of atopic eczema: Assessment of an emollient containing N-palmitoylethanolamine (ATOPA study)
    • Eberlein, B.; Eicke, C; Reinhardt, H.W.; Ring, J. Adjuvant treatment of atopic eczema: assessment of an emollient containing N-palmitoylethanolamine (ATOPA study). J. Eur. Acad. Dermatol. Venereol, 2008;22(1), 73-82.
    • (2008) J. Eur. Acad. Dermatol. Venereol , vol.22 , Issue.1 , pp. 73-82
    • Eberlein, B.1    Eicke, C.2    Reinhardt, H.W.3    Ring, J.4
  • 70
    • 37549064702 scopus 로고    scopus 로고
    • An optimized GC-MS method detects nanomolar amounts of anandamide in mouse brain
    • Muccioli, G.G.; Stella, N. An optimized GC-MS method detects nanomolar amounts of anandamide in mouse brain. Anal. Biochem., 2008, 373(2), 220-228.
    • (2008) Anal. Biochem , vol.373 , Issue.2 , pp. 220-228
    • Muccioli, G.G.1    Stella, N.2
  • 71
    • 33646521012 scopus 로고    scopus 로고
    • Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat
    • Murillo-Rodriguez, E.; Désarnaud, F.; Prospéro-García, O. Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat. Life Sci., 2006, 79(1), 30-37.
    • (2006) Life Sci , vol.79 , Issue.1 , pp. 30-37
    • Murillo-Rodriguez, E.1    Désarnaud, F.2    Prospéro-García, O.3
  • 72
    • 0037036436 scopus 로고    scopus 로고
    • Astrocytes in culture produce anandamide and other acylethanolamides
    • Walter, L.; Franklin, A.; Witting, A.; Moller, T.; Stella, N. Astrocytes in culture produce anandamide and other acylethanolamides. J. Biol. Chem., 2002, 277(23), 20869-20876.
    • (2002) J. Biol. Chem , vol.277 , Issue.23 , pp. 20869-20876
    • Walter, L.1    Franklin, A.2    Witting, A.3    Moller, T.4    Stella, N.5
  • 73
    • 37349006157 scopus 로고    scopus 로고
    • Microglia produce and hydrolyze palmitoylethanolamide
    • Muccioli, G.G.; Stella, N. Microglia produce and hydrolyze palmitoylethanolamide. Neuropharmacology, 2008, 54(1), 16-22.
    • (2008) Neuropharmacology , vol.54 , Issue.1 , pp. 16-22
    • Muccioli, G.G.1    Stella, N.2
  • 74
    • 0035902918 scopus 로고    scopus 로고
    • Receptor-dependent formation of endogenous cannabinoids in cortical neurons
    • Stella, N.; Piomelli, D. Receptor-dependent formation of endogenous cannabinoids in cortical neurons. Eur. J. Pharmacol, 2001, 425(3), 189-196.
    • (2001) Eur. J. Pharmacol , vol.425 , Issue.3 , pp. 189-196
    • Stella, N.1    Piomelli, D.2
  • 77
    • 0042320663 scopus 로고    scopus 로고
    • Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility
    • Franklin, A.; Parmentier-Batteur, S.; Walter, L.; Greenberg, DA.; Stella, N. Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility. J. Neurosci., 2003, 23(21), 7767-7775.
    • (2003) J. Neurosci , vol.23 , Issue.21 , pp. 7767-7775
    • Franklin, A.1    Parmentier-Batteur, S.2    Walter, L.3    Greenberg, D.A.4    Stella, N.5
  • 78
    • 1442348425 scopus 로고    scopus 로고
    • Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?
    • Berger, C.; Schmid, P.C.; Schabitz, W.R.; Wolf, M.; Schwab, S.; Schmid, H.H. Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia? J. Neurochem., 2004, 88(5), 1159-1167.
    • (2004) J. Neurochem , vol.88 , Issue.5 , pp. 1159-1167
    • Berger, C.1    Schmid, P.C.2    Schabitz, W.R.3    Wolf, M.4    Schwab, S.5    Schmid, H.H.6
  • 79
    • 5344277612 scopus 로고    scopus 로고
    • Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid
    • Sheerin, A.H.; Zhang, X.; Saucier, D.M.; Corcoran, M.E. Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid. Epilepsia., 2004, 45(10), 1184-1188.
    • (2004) Epilepsia , vol.45 , Issue.10 , pp. 1184-1188
    • Sheerin, A.H.1    Zhang, X.2    Saucier, D.M.3    Corcoran, M.E.4
  • 80
    • 74349084448 scopus 로고    scopus 로고
    • The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line
    • Duncan, R.S.; Chapman, K.D.; Koulen, P. The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line. Mol. Neurodegener., 2009, 4, 50.
    • (2009) Mol. Neurodegener , vol.4 , pp. 50
    • Duncan, R.S.1    Chapman, K.D.2    Koulen, P.3
  • 81
    • 79751535002 scopus 로고    scopus 로고
    • Palmitoylethanolamide protects dentate gyrus granule cells via peroxisome proliferator-activated receptor-alpha
    • Koch, M.; Kreutz, S.; Böttger, C.; Benz, A.; Maronde, E.; Ghadban, C.; Korf, H.W.; Dehghani, F. Palmitoylethanolamide protects dentate gyrus granule cells via peroxisome proliferator-activated receptor-alpha. Neurotox Res., 2011, 19(2), 330-340.
    • (2011) Neurotox Res , vol.19 , Issue.2 , pp. 330-340
    • Koch, M.1    Kreutz, S.2    Böttger, C.3    Benz, A.4    Maronde, E.5    Ghadban, C.6    Korf, H.W.7    Dehghani, F.8
  • 82
    • 0022498237 scopus 로고
    • N-acylethanolamine phospholipid metabolism in normal and ischemic rat brain
    • Natarajan, V.; Schmid, P.C.; Schmid, H.H. N-acylethanolamine phospholipid metabolism in normal and ischemic rat brain. Biochim. Biophys. Acta., 1986, 878(1), 32-41.
    • (1986) Biochim. Biophys. Acta , vol.878 , Issue.1 , pp. 32-41
    • Natarajan, V.1    Schmid, P.C.2    Schmid, H.H.3
  • 86
    • 79960209448 scopus 로고    scopus 로고
    • Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury
    • Esposito, E.; Paterniti, I.; Mazzon, E.; Genovese, T.; Di Paola, R.; Galuppo, M.; Cuzzocrea, S. Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. Brain Behav. Immun., 2011, 25(6), 1099-1112.
    • (2011) Brain Behav. Immun , vol.25 , Issue.6 , pp. 1099-1112
    • Esposito, E.1    Paterniti, I.2    Mazzon, E.3    Genovese, T.4    Di Paola, R.5    Galuppo, M.6    Cuzzocrea, S.7
  • 88
    • 0035542990 scopus 로고    scopus 로고
    • Microglial cells protect cerebellar granule neurons from apoptosis: Evidence for reciprocal signaling
    • Polazzi, E.; Gianni, T.; Contestabile, A. Microglial cells protect cerebellar granule neurons from apoptosis: evidence for reciprocal signaling. Glia., 2001, 36(3), 271-280.
    • (2001) Glia , vol.36 , Issue.3 , pp. 271-280
    • Polazzi, E.1    Gianni, T.2    Contestabile, A.3
  • 89
    • 51849168176 scopus 로고    scopus 로고
    • Neuron-microglia crosstalk up-regulates neuronal FGF-2 expression which mediates neuroprotection against excitotoxicity via JNK1/2
    • Figueiredo, C; Pais, TF.; Gomes, JR.; Chatterjee, S. Neuron-microglia crosstalk up-regulates neuronal FGF-2 expression which mediates neuroprotection against excitotoxicity via JNK1/2. J. Neurochem., 2008, 107(1), 73-85.
    • (2008) J. Neurochem , vol.107 , Issue.1 , pp. 73-85
    • Figueiredo, C.1    Pais, T.F.2    Gomes, J.R.3    Chatterjee, S.4
  • 90
    • 85027921135 scopus 로고    scopus 로고
    • Cell death/proliferation and alterations in glial morphology contribute to changes in diffusivity in the rat hippocampus after hypoxia-ischemia
    • Anderova, M.; Vorisek, I.; Pivonkova, H.; Benesova, J.; Vargova, L.; Cicanic, M.; Chvatal, A.; Sykova, E. Cell death/proliferation and alterations in glial morphology contribute to changes in diffusivity in the rat hippocampus after hypoxia-ischemia. J. Cereb. Blood Flow Metab., 2011, 31(3), 894-907.
    • (2011) J. Cereb. Blood Flow Metab , vol.31 , Issue.3 , pp. 894-907
    • Anderova, M.1    Vorisek, I.2    Pivonkova, H.3    Benesova, J.4    Vargova, L.5    Cicanic, M.6    Chvatal, A.7    Sykova, E.8
  • 91
    • 79959254383 scopus 로고    scopus 로고
    • Palmitoylethanolamide stimulation induces allopregnanolone synthesis in C6 cells and primary astrocytes: Involvement of peroxisome-proliferator activated receptor-a
    • Mattace Raso, G.; Esposito, E.; Vitiello, S.; Iacono, A.; Santoro, A.; D'Agostino, G.; Sasso, O.; Russo, R.; Piazza, PV.; Calignano, A.; Meli, R. Palmitoylethanolamide stimulation induces allopregnanolone synthesis in C6 cells and primary astrocytes: involvement of peroxisome-proliferator activated receptor-a. J. Neuroendocrinol., 2011, 23(7), 591-600.
    • (2011) J. Neuroendocrinol , vol.23 , Issue.7 , pp. 591-600
    • Mattace Raso, G.1    Esposito, E.2    Vitiello, S.3    Iacono, A.4    Santoro, A.5    D'Agostino, G.6    Sasso, O.7    Russo, R.8    Piazza, P.V.9    Calignano, A.10    Meli, R.11
  • 94
    • 84861191772 scopus 로고    scopus 로고
    • Palmitoylethanolamide Protects Against the Amyloid-p25-35-Induced Learning and Memory Impairment in Mice, an Experimental Model of Alzheimer Disease
    • D'Agostino, G.; Russo, R.; Avagliano, C; Cristiano, C; Meli, R.; Calignano, A. Palmitoylethanolamide Protects Against the Amyloid-p25-35-Induced Learning and Memory Impairment in Mice, an Experimental Model of Alzheimer Disease. Neuropsychopharmacology, 2012, (7), 1784-1792.
    • (2012) Neuropsychopharmacology , Issue.7 , pp. 1784-1792
    • D'Agostino, G.1    Russo, R.2    Avagliano, C.3    Cristiano, C.4    Meli, R.5    Calignano, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.