Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine

BMC Medicine

Volumn 11, Issue 1, 2013, Pages

  Hayes, Crystal D ^a   Dey, Debleena ^a   Palavicini, Juan P ^a   Wang, Hongjie ^a   Patkar, Kshitij A ^a   Minond, Dimitriy ^a   Nefzi, Adel ^a   Lakshmana, Madepalli K ^a  

^a TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

1; 3 bis (2 chloroethyl) 1 nitrosourea; Amyloid plaques; Amyloid ; Carmustine; Cytotoxicity; LDH release; MTT assay

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CARMUSTINE; SECRETASE; TRANSFORMING GROWTH FACTOR BETA;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CELL COUNT; CHO CELL; CHRONIC DRUG ADMINISTRATION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE MODEL; ENZYME INHIBITION; FEMALE; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INCUBATION TIME; MICROGLIA; MOTOR CORTEX; MOUSE; NONHUMAN; PROTEIN ANALYSIS; STABLE EXPRESSION;

ALZHEIMER DISEASE; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN; CARMUSTINE; CHO CELLS; CRICETINAE; CRICETULUS; DISEASE MODELS, ANIMAL; MICE; NEUROPROTECTIVE AGENTS; PLAQUE, AMYLOID; TREATMENT OUTCOME;

EID: 84875320351     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-11-81     Document Type: Article

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