Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 57, Issue 1, 2013, Pages 13-22

  Kraft, Theresia ^a   Witjas Paalberends, E Rosalie ^b   Boontje, Nicky M ^b   Tripathi, Snigdha ^a   Brandis, Almuth ^a   Montag, Judith ^a   Hodgkinson, Julie L ^a   Francino, Antonio ^c   Navarro Lopez, Francisco ^c   Brenner, Bernhard ^a   Stienen, Ger J M ^b   Van der Velden, Jolanda ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Myosin missense mutation R723G; Calcium sensitivity; Cardiomyocyte function; Familial hypertrophic cardiomyopathy; Myofibrillar disarray; Slow skeletal muscle

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; MYOSIN BINDING PROTEIN C; MYOSIN HEAVY CHAIN BETA; MYOSIN LIGHT CHAIN 2; TROPONIN I; TROPONIN T;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA MYHC GENE; CALCIUM EFFECT; CASE REPORT; CELL DENSITY; CONTROLLED STUDY; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; FEMALE; GENE; GENE FUNCTION; GENE MUTATION; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HUMAN; MALE; MUSCLE FIBRIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSICAL SENSITIVITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SOLEUS MUSCLE;

ADULT; CALCIUM; CARDIAC MYOSINS; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; FEMALE; GENE EXPRESSION; HEART VENTRICLES; HUMANS; ISOMETRIC CONTRACTION; MALE; MIDDLE AGED; MUSCLE PROTEINS; MUTATION, MISSENSE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; SARCOMERES; TROPONIN; YOUNG ADULT;

EID: 84875271449     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.01.001     Document Type: Article

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