Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy

Journal of Biological Chemistry

Volumn 277, Issue 43, 2002, Pages 40710-40716

  Robinson, Paul ^a   Mirza, Mahmooda ^b   Knott, Adam ^c   Abdulrazzak, Hassan ^a   Willott, Ruth ^b   Marston, Steven ^d   Hugh Watkins, Charles Redwood ^a,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; BIOLOGICAL ORGANS; CARDIOLOGY; ENZYMES;

DILATED CARDIOMYOPATHY (DCM); THIN FILAMENT REGULATION;

BIOCHEMISTRY;

ACTIN; ADENOSINE TRIPHOSPHATASE; CALCIUM ION; LYSINE; TROPOMYOSIN; TROPONIN T;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HEART DILATATION; HUMAN; HUMAN TISSUE; HYPERTROPHIC CARDIOMYOPATHY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; THIN FILAMENT;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CALCIUM; CARDIOMEGALY; CARDIOMYOPATHY, DILATED; HUMANS; MICROFILAMENTS; MUTATION; MYOCARDIUM; RABBITS; TROPONIN T;

ANIMALIA;

EID: 0037174918     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M203446200     Document Type: Article

References (46)

1. Keeling, P. J., Gang, Y., Smith, G., Seo, H., Bent, S. E., Murday, V., Caforio, A. L., and McKenna, W. J. (1995) Br. Heart J. 73, 417-421
2. Michels, V. V., Moll, P. P., Miller, F. A., Tajik, A. J., Chu, J. S., Driscoll, D. J., Burnett, J. C., Rodeheffer, R. J., Chesebro, J. H., and Tazelaar, H. D. (1992) N. Engl. J. Med. 326, 77-82
3. Seidman, J. G., and Seidman, C. (2001) Cell 104, 557-567
4. Schonberger, J., and Seidman, C. E. (2001) Am. J. Hum. Genet. 69, 249-260
5. Olson, T. M., Michels, V. V., Thibodeau, S. N., Tai, Y. S., and Keating, M. T. (1998) Science 280, 750-752
6. Kamisago, M., Sharma, S. D., DePalma, S. R., Solomon, S., Sharma, P., McDonough, B., Smoot, L., Mullen, M. P., Woolf, P. K., Wigle, E. D., Seidman, J. G., Seidman, C. E., Jarcho, J., and Shapiro, L. R. (2000) N. Engl. J. Med. 343, 1688-1696
7. Gerull, B., Gramlich, M., Atherton, J., McNabb, M., Trombitas, K., Sasse-Klaassen, S., Seidman, J. G., Seidman, C., Granzier, H., Labeit, S., Frenneaux, M., and Thierfelder, L. (2002) Nat. Genet. 30, 201-204
8. Olson, T. M., Kishimoto, N. Y., Whitby, F. G., and Michels, V. V. (2001) J. Mol. Cell Cardiol. 33, 723-732
9. Blair, E., Redwood, C., Ashrafian, H., Oliveira, M., Broxholme, J., Kerr, B., Salmon, A., Ostman-Smith, I., and Watkins, H. (2001) Hum. Mol. Genet. 10, 1215-1220
10. Redwood, C. S., Moolman-Smook, J. C., and Watkins, H. (1999) Cardiovasc. Res. 44, 20-36
11. Hernandez, O. M., Housmans, P. R., and Potter, J. D. (2001) J. Appl. Physiol. 90, 1125-1136
12. Sweeney, H. L., Feng, H. S., Yang, Z., and Watkins, H. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 14406-14410
13. Montgomery, D. E., Tardiff, J. C., and Chandra, M. (2001) J. Physiol. (Lond.) 536, 583-592
14. Franz, W. M., Muller, O. J., and Katus, H. A. (2001) Lancet 358, 1627-1637
15. Watkins, H. (2001) Eur., Heart J. 3, (suppl.) L43-L50
16. Marston, S. B., and Hodgkinson, J. L. (2001) J. Muscle Res. Cell Motil. 22, 1-4
17. Perry, S. V. (1998) J. Muscle Res. Cell Motil. 19, 575-602
18. Oberst, L., Zhao, G., Park, J. T., Brugada, R., Michael, L. H., Entman, M. L., Roberts, R., and Marian, A. J. (1998) J. Clin. Invest. 102, 1498-1505
19. Tardiff, J. C., Hewett, T. E., Palmer, B. M., Olsson, C., Factor, S. M., Moore, R. L., Robbins, J., and Leinwand, L. A. (1999) J. Clin. Invest. 104, 469-481
20. Morimoto, S., Yanaga, F., Minakami, R., and Ohtsuki, I. (1998)Am. J. Physiol. 275, C200-C207
21. Szczesna, D., Zhang, R., Zhao, J., Jones, M., Guzman, G., and Potter, J. D. (2000) J. Biol. Chem. 275, 624-630
22. Purcell, I. F., Bing, W., and Marston, S. B. (1999) Cardiovasc. Res. 43, 884-891
23. Knott, A., Purcell, I. F., and Marston, S. B. (2002) J. Mol. Cell. Cardiol. 34, 469-482
24. Redwood, C. S., Lohmann, K., Bing, W., Esposito, G. M., Elliott, K., Abdulrazzak, H., Knott, A., Purcell, I., Marston, S. B., and Watkins, H. (2000) Circ. Res. 86, 1146-1152
25. Elliott, K., Watkins, H., and Redwood, C. S. (2000) J. Biol. Chem. 275, 22069-22074
26. Bing, W., Fraser, I. D. C., and Marston, S. B. (1997) Biochem. J. 327, 335-340
27. Kron, S. J., Toyoshima, Y. Y., Uyeda, T. Q., and Spudich, J. A. (1991) Methods Enzymol. 196, 399-416
28. Marston, S. B., Fraser, I. D., Bing, W., and Roper, G. (1996) J. Muscle Res. Cell Motil. 17, 497-506
29. Burton, D., Abdulrazzak, H., Knott, A., Elliott, K., Redwood, C., Watkins, H., Marston, S., and Ashley, C. (2002) Biochem. J. 362, 443-451
30. Stefancsik, R., Jha, P. K., and Sarkar, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 957-962
31. Filatov, V. L., Katrukha, A. G., Bulargina, T. V., and Gusev, N. B. (1999) Biochemistry (Mosc.) 64, 969-985
32. Takeda, S., Yamashita, A., Maeda, K., and Maeda, Y. (2002) Biophys. J. 82, 170a
33. Potter, J. D., Sheng, Z., Pan, B. S., and Zhao, J. (1995) J. Biol. Chem. 270, 2557-2562
34. Geeves, M. A., and Lehrer, S. S. (1994) Biophys. J. 67, 273-282
35. Schaertl, S., Lehrer, S. S., and Geeves, M. A. (1995) Biochemistry 34, 15890-15894
36. Li, D., Czernuszewicz, G. Z., Gonzalez, O., Tapscott, T., Karibe, A., Durand, J. B., Brugada, R., Hill, R., Gregoritch, J. M., Anderson, J. L., Quinones, M., Bachinski, L. L., and Roberts, R. (2001) Circulation 104, 2188-2193
37. Morimoto, S., Lu, Q. W., Harada, K., Takahashi-Yanaga, F., Minakami, R., Ohta, M., Sasaguri, T., and Ohtsuki, I. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 913-918
38. Hajjar, R. J., Grossman, W., and Gwathmey, J. K. (1992) Basic. Res. Cardiol. 87 Suppl. 1, 143-159
39. Ruf, T., Schulte-Baukloh, H., Ludemann, J., Posival, H., Beyersdorf, F., Just, H., and Holubarsch, C. (1998) Cardiovasc. Res. 40, 580-590
40. de Tombe, P. P. (1998) Cardiovasc. Res. 37, 367-380
41. Wolff, M. R., Buck, S. H., Stoker, S. W., Greaser, M. L., and Mentzer, R. M. (1996) J. Clin. Invest. 98, 167-176
42. Hajjar, R. J., Schwinger, R. H., Schmidt, U., Kim, C. S., Lebeche, D., Doye, A. A., and Gwathmey, J. K. (2000) Circulation 101, 1679-1685
43. van der Velden, J., Klein, L. J., Zaremba, R., Boontje, N. M., Huybregts, M. A., Stooker, W., Eijsman, L., de Jong, J. W., Visser, C. A., Visser, F. C., and Stienen, G. J. (2001) Circulation 104, 1140-1146
44. Perez, N. G., Hashimoto, K., McCune, S., Altschuld, R. A., and Marban, E. (1999) Circulation 99, 1077-1083
45. Tobacman, L. S., Lin, D., Butters, C., Landis, C., Back, N., Pavlov, D., and Homsher, E. (1999) J. Biol. Chem. 274, 28363-28370
46. Knollmann, B. C., and Potter, J. D. (2001) Trends Cardiovasc. Med. 11, 206-212