Protein kinase A phosphorylates titin's cardiac-specific N2B domain and reduces passive tension in rat cardiac myocytes

Circulation Research

Volumn 90, Issue 11, 2002, Pages 1181-1188

  Yamasaki, R ^a   Wu, Y ^a   McNabb, M ^a   Greaser, M ^a   Labeit, S ^a   Granzier, H ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

adrenergic signaling; Connectin; Diastole; Myocyte mechanics; Resting tension

Indexed keywords

CONNECTIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; RECOMBINANT PROTEIN;

ADRENERGIC SYSTEM; ANIMAL CELL; ARTICLE; BETA ADRENERGIC STIMULATION; DIASTOLE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEART FUNCTION; HEART MUSCLE CELL; MALE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; SARCOMERE; TENSION;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BINDING SITES; BIOMECHANICS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HEART VENTRICLES; ISOPROTERENOL; MALE; MICROSCOPY, IMMUNOELECTRON; MUSCLE PROTEINS; PHOSPHORYLATION; PROPRANOLOL; PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; SARCOMERES;

EID: 0037076791     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000021115.24712.99     Document Type: Article

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