메뉴 건너뛰기




Volumn 79, Issue 3, 2008, Pages 481-491

The molecular phenotype of human cardiac myosin associated with hypertrophic obstructive cardiomyopathy

Author keywords

Contractile apparatus; Contractile function; Hypertrophic cardiomyopathy; Hypertrophy; Myectomy; Myosin; Protein phosphorylation

Indexed keywords

ACETYLSALICYLIC ACID; AMIODARONE; ATENOLOL; CARDIAC MYOSIN; CLOPIDOGREL; DISOPYRAMIDE; FRUMIL; ISOPROTEIN; MYOSIN HEAVY CHAIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 2; PHOSPHOPROTEIN; PROPRANOLOL DERIVATIVE; QUININE; TIMOLOL; VERAPAMIL;

EID: 48749118698     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn094     Document Type: Article
Times cited : (40)

References (40)
  • 1
    • 0033214976 scopus 로고    scopus 로고
    • Properties of mutant contractile proteins that cause hypertrophic cardiomyopathy
    • Redwood CS, Moolman-Smook JC, Watkins H. Properties of mutant contractile proteins that cause hypertrophic cardiomyopathy. Cardiovasc Res 1999;44:20-36.
    • (1999) Cardiovasc Res , vol.44 , pp. 20-36
    • Redwood, C.S.1    Moolman-Smook, J.C.2    Watkins, H.3
  • 2
    • 0037630018 scopus 로고    scopus 로고
    • Hypertrophic cardiomyopathy distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy
    • Richard P, Charron P, Carrier L, Ledeuil C, Cheav T, Pichereau C et al. Hypertrophic cardiomyopathy distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy. Circulation 2003;107:2227-2232.
    • (2003) Circulation , vol.107 , pp. 2227-2232
    • Richard, P.1    Charron, P.2    Carrier, L.3    Ledeuil, C.4    Cheav, T.5    Pichereau, C.6
  • 3
    • 4043081356 scopus 로고    scopus 로고
    • Comprehensive analysis of the beta-myosin heavy chain gene in 389 unrelated patients with hypertrophic cardiomyopathy
    • Van Driest SL, Jaeger MA, Ommen SR, Will ML, Gersh BJ, Tajik AJ et al. Comprehensive analysis of the beta-myosin heavy chain gene in 389 unrelated patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 2004;44:602-610.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 602-610
    • Van Driest, S.L.1    Jaeger, M.A.2    Ommen, S.R.3    Will, M.L.4    Gersh, B.J.5    Tajik, A.J.6
  • 5
    • 0034796231 scopus 로고    scopus 로고
    • Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy
    • Knollmann BC, Potter JD. Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy. Trends Cardiovasc Med 2001;11:206-212.
    • (2001) Trends Cardiovasc Med , vol.11 , pp. 206-212
    • Knollmann, B.C.1    Potter, J.D.2
  • 6
    • 0037174918 scopus 로고    scopus 로고
    • Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy
    • Robinson PJR, Mirza M, Knott A, Abdulrazzak H, Marston S, Watkins H et al. Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy. J Biol Chem 2002;277:40710-40716.
    • (2002) J Biol Chem , vol.277 , pp. 40710-40716
    • Robinson, P.J.R.1    Mirza, M.2    Knott, A.3    Abdulrazzak, H.4    Marston, S.5    Watkins, H.6
  • 8
    • 0034494362 scopus 로고    scopus 로고
    • R403Q and L908V mutant beta-cardiac myosin from patients with familial hypertrophic cardiomyopathy exhibit enhanced mechanical performance at the single molecule level
    • Palmiter KA, Tyska MJ, Haeberle JR, Alpert NR, Fananapazir L, Warshaw DM. R403Q and L908V mutant beta-cardiac myosin from patients with familial hypertrophic cardiomyopathy exhibit enhanced mechanical performance at the single molecule level. J Musc Res Cell Motil 2000;21:609-620.
    • (2000) J Musc Res Cell Motil , vol.21 , pp. 609-620
    • Palmiter, K.A.1    Tyska, M.J.2    Haeberle, J.R.3    Alpert, N.R.4    Fananapazir, L.5    Warshaw, D.M.6
  • 9
    • 0034721807 scopus 로고    scopus 로고
    • Transgenic modelling of a cardiac troponin I mutation linked to familial hypertrophic cardiomyopathy
    • James J, Zhang Y, Osonska H, Sanbe A, Klevitsky R, Hewett TE et al. Transgenic modelling of a cardiac troponin I mutation linked to familial hypertrophic cardiomyopathy. Circ Res 2000;87:805-811.
    • (2000) Circ Res , vol.87 , pp. 805-811
    • James, J.1    Zhang, Y.2    Osonska, H.3    Sanbe, A.4    Klevitsky, R.5    Hewett, T.E.6
  • 10
    • 0032526155 scopus 로고    scopus 로고
    • A truncated troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy
    • Tardiff JC, Factor SM, Tompkins BD, Hewett TE, Palmer BM, Moore RL et al. A truncated troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. J Clin Invest 1998;101:2800-2811.
    • (1998) J Clin Invest , vol.101 , pp. 2800-2811
    • Tardiff, J.C.1    Factor, S.M.2    Tompkins, B.D.3    Hewett, T.E.4    Palmer, B.M.5    Moore, R.L.6
  • 11
    • 33947531466 scopus 로고    scopus 로고
    • Reviews of translational medicine and genomics in cardiovascular disease: New disease taxonomy and therapeutic implications cardiomyopathies - therapeutics based on molecular phenotype
    • Ashrafian H, Watkins H. Reviews of translational medicine and genomics in cardiovascular disease: new disease taxonomy and therapeutic implications cardiomyopathies - therapeutics based on molecular phenotype. J Am Coll Cardiol 2007;49:1251-1264.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1251-1264
    • Ashrafian, H.1    Watkins, H.2
  • 13
    • 13944269529 scopus 로고    scopus 로고
    • Hypertrophic cardiomyopathy-related beta-myosin mutations cause highly variable calcium sensitivity with functional imbalances among individual muscle cells
    • Kirschner SE, Becker E, Antognozzi M, Kubis HP, Francino A, Navarro-Lopez F et al. Hypertrophic cardiomyopathy-related beta-myosin mutations cause highly variable calcium sensitivity with functional imbalances among individual muscle cells. Am J Physiol Heart Circ Physiol 2005;288:H1242- H1251.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Kirschner, S.E.1    Becker, E.2    Antognozzi, M.3    Kubis, H.P.4    Francino, A.5    Navarro-Lopez, F.6
  • 14
    • 33748080756 scopus 로고    scopus 로고
    • Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy
    • Elliott PM, Gimeno JR, Tome MT, Shah J, Ward D, Thaman R et al. Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy. Eur Heart J 2006;27:1933-1941.
    • (2006) Eur Heart J , vol.27 , pp. 1933-1941
    • Elliott, P.M.1    Gimeno, J.R.2    Tome, M.T.3    Shah, J.4    Ward, D.5    Thaman, R.6
  • 15
    • 0036800523 scopus 로고    scopus 로고
    • Septal myotomy-myectomy and transcoronary septal alcohol ablation in hypertrophic obstructive cardiomyopathy: A comparison of clinical, haemodynamic and exercise outcomes
    • Firoozi S, Elliott PM, Sharma S, Murday A, Brecker SJ, Hamid MS et al. Septal myotomy-myectomy and transcoronary septal alcohol ablation in hypertrophic obstructive cardiomyopathy: a comparison of clinical, haemodynamic and exercise outcomes. Eur Heart J 2002;23:1617-1624.
    • (2002) Eur Heart J , vol.23 , pp. 1617-1624
    • Firoozi, S.1    Elliott, P.M.2    Sharma, S.3    Murday, A.4    Brecker, S.J.5    Hamid, M.S.6
  • 16
    • 0016682585 scopus 로고
    • Operative treatment in hypertrophic subaortic stenosis: Techniques and the results of pre- and postoperative assessments in 83 patients
    • Morrow AG, Reitz BA, Epstein SE, Henry WL, Conkle DM, Itscoitz SB et al. Operative treatment in hypertrophic subaortic stenosis: techniques and the results of pre- and postoperative assessments in 83 patients. Circulation 1975;52:88-102.
    • (1975) Circulation , vol.52 , pp. 88-102
    • Morrow, A.G.1    Reitz, B.A.2    Epstein, S.E.3    Henry, W.L.4    Conkle, D.M.5    Itscoitz, S.B.6
  • 17
    • 33845778948 scopus 로고    scopus 로고
    • Troponin phosphorylation and regulatory function in human heart muscle: Dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure
    • Messer AE, Jacques AM, Marston SB. Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure. J Mol Cell Cardiol 2007;42:247-259.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 247-259
    • Messer, A.E.1    Jacques, A.M.2    Marston, S.B.3
  • 18
    • 0028953460 scopus 로고
    • 2+: The thin filament is switched as a single cooperative unit
    • 2+: the thin filament is switched as a single cooperative unit. J Biol Chem 1995;270:7836-7841.
    • (1995) J Biol Chem , vol.270 , pp. 7836-7841
    • Fraser, I.D.C.1    Marston, S.B.2
  • 19
    • 17744416349 scopus 로고    scopus 로고
    • Changes in essential myosin light chain isoform expression provide a molecular basis for isometric force regulation in the failing human heart
    • Morano I, Hadicke K, Haase H, Bohm M, Erdmann E, Schaub MC. Changes in essential myosin light chain isoform expression provide a molecular basis for isometric force regulation in the failing human heart. J Mol Cell Cardiol 1997;29:1177-1187.
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 1177-1187
    • Morano, I.1    Hadicke, K.2    Haase, H.3    Bohm, M.4    Erdmann, E.5    Schaub, M.C.6
  • 21
    • 0028860791 scopus 로고
    • Reduced contraction and altered frequency response of isolated ventricular myocytes from patients with heart failure
    • Davies CH, Davia K, Bennett JG, Pepper JR, Poole-Wilson PA, Harding SE. Reduced contraction and altered frequency response of isolated ventricular myocytes from patients with heart failure. Circulation 1995;92:2540-2549.
    • (1995) Circulation , vol.92 , pp. 2540-2549
    • Davies, C.H.1    Davia, K.2    Bennett, J.G.3    Pepper, J.R.4    Poole-Wilson, P.A.5    Harding, S.E.6
  • 23
    • 0030721473 scopus 로고    scopus 로고
    • 2+-dependant effects on actin-tropomyosin filament motility
    • 2+-dependant effects on actin-tropomyosin filament motility. Biochem J 1997;327:335-340.
    • (1997) Biochem J , vol.327 , pp. 335-340
    • Bing, W.1    Fraser, I.D.C.2    Marston, S.B.3
  • 24
    • 9744230560 scopus 로고    scopus 로고
    • Cardiac myosin isoforms from different species have unique enzymatic and mechanical properties
    • Malmqvist UP, Aronshtam A, Lowey S. Cardiac myosin isoforms from different species have unique enzymatic and mechanical properties. Biochemistry 2004;43:15058-15065.
    • (2004) Biochemistry , vol.43 , pp. 15058-15065
    • Malmqvist, U.P.1    Aronshtam, A.2    Lowey, S.3
  • 26
    • 0142187316 scopus 로고    scopus 로고
    • Random walks with thin filaments: Application of in vitro motility assay to the study of actomyosin regulation
    • Marston S. Random walks with thin filaments: application of in vitro motility assay to the study of actomyosin regulation. J Musc Res Cell Motil 2003;24:149-156.
    • (2003) J Musc Res Cell Motil , vol.24 , pp. 149-156
    • Marston, S.1
  • 29
    • 48749119251 scopus 로고    scopus 로고
    • Electromechanical properties of isolated myocardium from patients with hypertrophic obstructive cardiomyopathy (HOCM)
    • Gray R, Jacques A, Peters N, McKenna W, Walker J, McIntyre H et al. Electromechanical properties of isolated myocardium from patients with hypertrophic obstructive cardiomyopathy (HOCM). Circulation 2005;112(17 Supp 15):U149.
    • (2005) Circulation , vol.112 , Issue.17 SUPP 15
    • Gray, R.1    Jacques, A.2    Peters, N.3    McKenna, W.4    Walker, J.5    McIntyre, H.6
  • 30
    • 0030855107 scopus 로고    scopus 로고
    • Abnormal action potential conduction in isolated human hypertrophied left ventricular myocardium
    • McIntyre H, Fry CH. Abnormal action potential conduction in isolated human hypertrophied left ventricular myocardium. J Cardiovasc Electrophysiol 1997;8:887-894.
    • (1997) J Cardiovasc Electrophysiol , vol.8 , pp. 887-894
    • McIntyre, H.1    Fry, C.H.2
  • 31
    • 0037216694 scopus 로고    scopus 로고
    • 2+ sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins
    • 2+ sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins. Cardiovasc Res 2003;57:37-47.
    • (2003) Cardiovasc Res , vol.57 , pp. 37-47
    • van der Velden, J.1    Papp, Z.2    Zaremba, R.3    Boontje, N.M.4    de Jong, J.W.5    Owen, V.J.6
  • 32
    • 48749109518 scopus 로고    scopus 로고
    • Post-translational modification of TnT, TnI, MyBP-C and MLC-2 in HOCM human heart muscle
    • abstract#3:9, doi:10.1007/S10974-008- 9127-Z
    • Gallon CE, Messer AE, Copeland O, Jacques A, Tsang V, McKenna WJ et al. Post-translational modification of TnT, TnI, MyBP-C and MLC-2 in HOCM human heart muscle. J Muscle Res Cell Motil 2007, doi:10.1007/S10974-008- 9127-Z abstract#3:9.
    • J Muscle Res Cell Motil , vol.2007
    • Gallon, C.E.1    Messer, A.E.2    Copeland, O.3    Jacques, A.4    Tsang, V.5    McKenna, W.J.6
  • 33
    • 34447526253 scopus 로고    scopus 로고
    • Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure
    • El-Armouche A, Pohlmann L, Schlossarek S, Starbatty J, Yeh YH, Nattel S et al. Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure. J Mol Cell Cardiol 2007;43:223-229.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 223-229
    • El-Armouche, A.1    Pohlmann, L.2    Schlossarek, S.3    Starbatty, J.4    Yeh, Y.H.5    Nattel, S.6
  • 34
    • 48749084331 scopus 로고    scopus 로고
    • Evidence for reduced troponin I phosphorylation and altered troponin function in patients with hypertrophic obstructive cardiomyopathy
    • Jacques A, Messer A, Tsang V, McKenna W, Marston S. Evidence for reduced troponin I phosphorylation and altered troponin function in patients with hypertrophic obstructive cardiomyopathy. J Mol Cell Cardiol 2006;40:939.
    • (2006) J Mol Cell Cardiol , vol.40 , pp. 939
    • Jacques, A.1    Messer, A.2    Tsang, V.3    McKenna, W.4    Marston, S.5
  • 35
    • 30944461059 scopus 로고    scopus 로고
    • Thick filament proteins and performance in human heart failure
    • Palmer BM. Thick filament proteins and performance in human heart failure. Heart Fail Rev 2005;10:187-197.
    • (2005) Heart Fail Rev , vol.10 , pp. 187-197
    • Palmer, B.M.1
  • 37
    • 34547185623 scopus 로고    scopus 로고
    • Oxidative stress and redox signalling in cardiac hypertrophy and heart failure
    • Seddon M, Looi YH, Shah AM. Oxidative stress and redox signalling in cardiac hypertrophy and heart failure. Heart 2007;93:903-907.
    • (2007) Heart , vol.93 , pp. 903-907
    • Seddon, M.1    Looi, Y.H.2    Shah, A.M.3
  • 40
    • 33645806344 scopus 로고    scopus 로고
    • Focalized contractile impairment at hypertrophied myocardium proven in consideration of wall stress in patients with hypertrophic cardiomyopathy
    • Yamazaki T, Suzuki J, Shimamoto R, Tsuji T, Ohmoto Y, Toyo-Oka T et al. Focalized contractile impairment at hypertrophied myocardium proven in consideration of wall stress in patients with hypertrophic cardiomyopathy. Int Heart J 2006;47:247-258.
    • (2006) Int Heart J , vol.47 , pp. 247-258
    • Yamazaki, T.1    Suzuki, J.2    Shimamoto, R.3    Tsuji, T.4    Ohmoto, Y.5    Toyo-Oka, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.