Malignant hypertrophic cardiomyopathy caused by the Arg723Gly mutation in β-myosin heavy chain gene

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 12, 2000, Pages 2307-2313

  Enjuto, Montserrat ^a   Francino, Antonio ^a   Navarro López, Francisco ^a   Viles, Dolors ^a   Paré, Juan Carlos ^a   Ballesta, Antonio M ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Beta myosin heavy chain; Echocardiography; Gene mutations; Hypertrophic cardiomyopathy

Indexed keywords

AMINO ACID; ARGININE; CELL PROTEIN; DNA; GLYCINE; MYOSIN HEAVY CHAIN;

ADULT; AGED; ARTICLE; DNA SEQUENCE; ECHOCARDIOGRAPHY; FEMALE; GENE MUTATION; GENETIC CODE; HEART FAILURE; HEART TRANSPLANTATION; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; LIFE EXPECTANCY; MAJOR CLINICAL STUDY; MALE; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION MAPPING; SARCOMERE; SINGLE STRAND CONFORMATION POLYMORPHISM; SUDDEN DEATH; SURVIVAL RATE;

EID: 0034502475     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1260     Document Type: Article

References (17)

1. Implications of left ventricular remodeling in hypertrophic cardiomyopathy
2. Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy
3. Structural analysis of the titin gene in hypertrophic cardiomyopathy: Identification of a novel disease gene
4. Coexistence of sudden cardiac death and end-stage heart failure in familial hypertrophic cardiomyopathy
5. Molecular basis of familial cardiomyopathies
6. Problems in echocardiographic volume determinations: Echocardiographic-angiographic correlations in the presence or absence of asynergy
7. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
8. Exclusion of cardiac myosin heavy chain and actin gene involvement in hypertrophic cardiomyopathy of several French families
9. Occurrence and significance of progressive left ventricular wall thinning and relative cavity dilation in hypertrophic cardiomyopathy
10. Structural interpretation of the mutations in the ?:cardiac myosin that have been implicated in familial hypertrophic cardiomyopathy
11. Structure of the Actin-Myosin complex and its implications for muscle contraction
12. The neck region of the myosin motor domain acts as a lever arm to generate movement
13. Sporadic hypertrophic cardiomyopathy due to de novo mutations
14. Prognostic implications of novel β-cardiac myosin heavy chain gene mutations that cause familial hypertrophic cardiomyopathy
15. Early expression of a malignant phenotype of familial hypertrophic cardiomyopathy associated with a Gly716Arg myosin heavy chain mutation in a Korean family
16. Characterization of mutant myosins of Dictyostelium discoideum equivalent to human familial hypertrophic cardiomyopathy mutants. Molecular force level of mutant myosins may have a prognostic implication
17. Diagnostic value of electrocardiography and echocardiography for familial hypertrophic cardiomyopathy in a genotyped adult population