The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome

Immunobiology

Volumn 218, Issue 4, 2013, Pages 664-673

  Schweneker, Katrin ^a   Gorka, Oliver ^a   Schweneker, Marc ^a   Poeck, Hendrik ^a   Tschopp, Jürg ^b   Peschel, Christian ^a   Ruland, Jürgen ^a,c   Groß, Olaf ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Adjuvant; Inflammasome; Nlrp3; TDB; Tuberculosis

Indexed keywords

ADAPTOR PROTEIN; CHEMOKINE; CORD FACTOR; CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; POTASSIUM; PROTEIN CARD9; REACTIVE OXYGEN METABOLITE; TREHALOSE 6,6' DIBEHENATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; LYSOSOME; MOUSE; NEUTROPHIL; NONHUMAN; POTASSIUM CELL LEVEL; POTASSIUM TRANSPORT; PRIORITY JOURNAL; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADJUVANTS, IMMUNOLOGIC; ANIMALS; CARRIER PROTEINS; CASPASE 1; CHEMOKINES; CORD FACTORS; GLYCOLIPIDS; IMMUNITY, INNATE; INFLAMMASOMES; INTERLEUKIN-1BETA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES;

EID: 84875257761     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2012.07.029     Document Type: Article

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