Paeoniflorin protects human EA.hy926 endothelial cells against gamma-radiation induced oxidative injury by activating the NF-E2-related factor 2/heme oxygenase-1 pathway

Toxicology Letters

Volumn 218, Issue 3, 2013, Pages 224-234

  Yu, Jing ^a   Zhu, Xiaoyun ^b   Qi, Xin ^b   Che, Juanjuan ^a   Cao, Bangwei ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Department of Oncology   (China)

Author keywords

Heme oxygenase 1; Nuclear factor erythroid 2 related factor 2; Oxidative stress; Paeoniflorin; Reactive oxygen species

Indexed keywords

GLUTATHIONE; HEME OXYGENASE 1; LACTATE DEHYDROGENASE; MALONALDEHYDE; PAEONIFLORIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; GAMMA RADIATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; BENZOATES; BRIDGED COMPOUNDS; CELL LINE; CELL SURVIVAL; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUCOSIDES; GLUTATHIONE; HEME OXYGENASE-1; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; L-LACTATE DEHYDROGENASE; MALONDIALDEHYDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTOPORPHYRINS; RADIATION-PROTECTIVE AGENTS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSFECTION; UP-REGULATION;

EID: 84875235419     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.01.028     Document Type: Article

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