NRF2 deficiency reduces life span of mice administered thoracic irradiation

Free Radical Biology and Medicine

Volumn 51, Issue 6, 2011, Pages 1175-1183

  Travis, Elizabeth L ^a   Rachakonda, Girish ^b   Zhou, Xinhui ^a   Korhonen, Katrina ^b   Sekhar, Konjeti R ^b   Biswas, Swati ^b   Freeman, Michael L ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

Free radicals; FSP 1; Late normal tissue injury; NRF2; Nrf2 null mice; PAI 1; Radiation induced fibrosis; TGF

Indexed keywords

CALVASCULIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; IRRADIATION; LIFESPAN; LUNG ALVEOLUS; LUNG FIBROBLAST; LUNG PARENCHYMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THORAX IRRADIATION;

ANIMALS; FIBROBLASTS; HUMANS; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; PLASMINOGEN ACTIVATOR INHIBITOR 1; RADIATION INJURIES, EXPERIMENTAL; RADIATION PNEUMONITIS; RADIATION, IONIZING; RADIOTHERAPY; S100 PROTEINS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 80051782981     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.05.038     Document Type: Article

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