Postischemic hyperactivity in the Mongolian gerbil correlates with loss of hippocampal neurons

Behavioral Neuroscience

Volumn 111, Issue 6, 1997, Pages 1205-1216

  Andersen, Maibritt B ^a,c   Zimmer, Jens ^b   Sams Dodd, Frank ^a  

^a H LUNDBECK A S   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CELL LOSS; COMMON CAROTID ARTERY; CONTROLLED STUDY; GERBIL; HABITUATION; HIPPOCAMPUS; HYPERACTIVITY; LOCOMOTION; NERVE CELL; NONHUMAN;

ANIMALS; ASTROCYTES; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; GERBILLINAE; HIPPOCAMPUS; HYPERKINESIS; ISCHEMIA; MALE; MOTOR ACTIVITY; NEOSTRIATUM; TIME FACTORS;

EID: 0345244850     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.111.6.1205     Document Type: Article

References (29)

1. Amano, A., Hasegawa, M., Hasegawa, T., & Nabeshima, T. (1993). Characteristics of transient cerebral ischemia-induced deficits on various learning and memory tasks in male Mongolian gerbils. Japanese Journal of Pharmacology, 63, 469-477.
2. Amaral, D. G., & Witter, M. P. (1995). Hippocampal formation. In G. Paxinos (Ed.), The rat nervous system (pp. 443-493). San Diego: Academic Press.
3. Babcock, A. M., Baker, D. A., & Lovec, R. (1993). Locomotor activity in the ischemic gerbil. Brain Research, 625, 351-354.
4. Castellano, B., Gonzáles, B., Jensen, M. B., Pedersen, E. B., Finsen, B. R., & Zimmer, J. (1991). A double staining technique for simultaneous demonstration of astrocytes and microglia in brain sections and astroglial cell cultures. The Journal of Histochemistry and Cytochemistry; 39, 561-568.
5. Chandler, M. J., DeLeo, J., & Carney, J. M. (1985). An unanesthe- tized-gerbil model of cerebral ischemia-induced behavioral changes. Journal of Pharmacological Methods, 14, 137-146.
6. Colbourne, F., & Corbett, D. (1995). Delayed postischemic hypothermia: A six month survival study using behavioral and histological assessments of neuroprotection. Journal of Neuroscience, 15, 7250-7260.
7. Corbett, D., Evans, S. J., & Nurse, S. M. (1992). Impaired acquisition of the Morris water maze following global ischemic damage in the gerbil. NeuroReport, 3, 204-206.
8. Finsen, B., Sørensen, T., Castellano, B., Pedersen, E. B., & Zimmer, J. (1991). Leukocyte infiltration and glial reactions in xenografts of mouse brain tissue undergoing rejection in the adult rat brain: A light and electron microscopical immunocytochemical study. Journal of Neuroimmunology, 32, 159-183.
9. Gerhardt, S. C., & Boast, C. A. (1988). Motor activity changes following cerebral ischemia in gerbils are correlated with the degree of neuronal degeneration in hippocampus. Behavioral Neuroscience, 102, 301-303.
10. Glickman, S. E., Higgins, T. J., & Isaacson, R. L. (1970). Some effects of hippocampal lesions on the behavior of Mongolian gerbils. Physiology & Behavior, 5, 931-938.
11. Hagan, J. J., & Beaughard, M. (1990). The effects of forebrain ischaemia on spatial learning. Behavioural Brain Research, 41, 151-160.
12. Jarrard, L. E. (1989). On the use of ibotenic acid to lesion selectively different components of the hippocampal formation. Journal of Neuroscience Methods, 29, 251-259.
13. Jarrard, L. E. (1993). On the role of the hippocampus in learning and memory in the rat. Behavioral and Neural Biology, 60, 9-26.
14. Jørgensen, M. B., Finsen, B. R., Jensen, M. B., Castellano, B., Diemer, N. H., and Zimmer, J. (1993). Microglial and astroglial reactions to ischemic and kainic acid-induced lesions of the adult rat hippocampus. Experimental Neurology, 120, 70-88.
15. Karasawa, Y., Araki, H., & Otomo, S. (1994). Changes in locomotor activity and passive avoidance task performance induced by cerebral ischemia in Mongolian gerbils. Stroke, 25, 645-650.
16. Katoh, A., Ishibashi, C., Shiomi, T., Takahara, Y., & Eigyo, M. (1992). Ischemia-induced irreversible deficit of memory function in gerbils. Brain Research, 577, 57-63.
17. Kuroiwa, T., Bonnekoh, P., & Hossmann, K.-A. (1991). Locomotor hyperactivity and hippocampal CA1 injury after transient forebrain ischemia of gerbils. Neuroscience Letters, 122, 141-144.
18. Loskota, J. W., Lomax, P., & Verity, M. A. (1974). A siereotaxic atlas of the Mongolian gerbil brain (Meriones unguiculatus). Ann Arbor, MI: Ann Arbor Science.
19. Mileson, B. E., & Schwartz, R. D. (1991). The use of locomotor activity as a behavioral screen for neuronal damage following transient forebrain ischemia in gerbils. Neuroscience Letters, 128, 71-76.
20. Nurse, S., & Corbett, D. (1994). Direct measurement of brain temperature during and after intraischemic hypothermia: Correlation with behavioral, physiological, and histological endpoints. Journal of Neuroscience, 14, 7726-7734.
21. O'Keefe, J. (1971). The hippocampus as a spatial map: Preliminary evidence from unit activity in the freely-moving rat. Brain Research, 34, 171-175.
22. O'Keefe, J., & Nadel, L. (1978). The hippocampus as a cognitive map. Oxford, England: Clarendon Press.
23. O'Neill, M., Caldwell, M., Earley, B., Canney, M., O'Halloran, A., Kelly, J., Leonard, B. E., & Junien, J.-L. (1995). The a receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia. European Journal of Pharmacology, 283, 217-225.
24. O'Neill, M., Canney, M., Earley, B., Junien, J.-L., & Leonard, B. E. (1996). The novel sigma ligand JO 1784 protects against ischaemia-induced behavioural changes, cell death and receptor dysfunction in the gerbil. Neurochemistry International. 28(2), 193-207.
25. Phillis, J. W. (1995). CI-966, a GABA uptake inhibitor, antagonizes ischemia-induced neuronal degeneration in the gerbil. General Pharmacology, 26, 1061-1064.
26. Phillis, J. W. (1996). Cerebroprotective action of the phospholipase inhibitor Quinacrine in the ischemia/reperfused gerbil hippocampus. Life Sciences, 58, PL97-PL101.
27. Sams-Dodd, F. (1995). Automation of the social interaction test by a video-tracking system: Behavioural effects of repeated phencyclidine treatment. Journal of Neuroscience Methods, 59, 157-167.
28. Sams-Dodd, F. (1996). Phencyclidine-induced stereotyped behaviour and social isolation in rats: A possible animal model of schizophrenia. Behavioural Pharmacology, 7, 3-23.
29. Wang, D., & Corbett, D. (1990). Cerebral ischemia, locomotor activity and spatial mapping. Brain Research, 533, 78-82.