Rapamycin protects heart from ischemia/reperfusion injury independent of autophagy by activating PI3 kinase-Akt pathway and mitochondria KATP channel

Pharmazie

Volumn 65, Issue 10, 2010, Pages 760-765

  Yang, Shu Sen ^b   Liu, You Bin ^a   Yu, Jiang Bo ^b   Fan, Ying ^b   Tang, Shou Yi ^b   Duan, Wen Tao ^b   Wang, Zheng ^b   Gan, Run Tao ^b   Yu, Bo ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 3 METHYLADENINE; 5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATASE (POTASSIUM); MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; POTASSIUM CHANNEL; PROTEIN KINASE B; RAPAMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISOLATED HEART; MALE; MITOCHONDRION; NONHUMAN; RAT; REPERFUSION INJURY;

ANIMALS; ANTI-BACTERIAL AGENTS; AUTOPHAGY; BLOTTING, WESTERN; CARDIOTONIC AGENTS; CORONARY CIRCULATION; HEART FUNCTION TESTS; HEMODYNAMICS; KATP CHANNELS; MALE; MITOCHONDRIA, HEART; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; RATS; RATS, WISTAR; SIROLIMUS;

EID: 78349242462     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2010.0576     Document Type: Article

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