Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway

Cellular and Molecular Life Sciences

Volumn 70, Issue 6, 2013, Pages 1123-1133

  Rodriguez Araujo, Gerardo ^a   Nakagami, Hironori ^a,b   Hayashi, Hiroki ^a   Mori, Masaki ^a   Shiuchi, Tetsuya ^c   Minokoshi, Yasuhiko ^c   Nakaoka, Yoshikazu ^a   Takami, Yoichi ^a   Komuro, Issei ^a   Morishita, Ryuichi ^a   Kaneda, Yasufumi ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

Adipocytes; Alpha synuclein; Gab1; Glucose uptake; Glucose utilization; Myocytes

Indexed keywords

ADAPTOR PROTEIN; ALPHA SYNUCLEIN; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHATIDIC ACID RECEPTOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN GAB1; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; IN VITRO STUDY; IN VIVO STUDY; METABOLIC REGULATION; MOUSE; NONHUMAN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADIPOCYTES; ALPHA-SYNUCLEIN; ANALYSIS OF VARIANCE; ANIMALS; CALORIMETRY, INDIRECT; CELL LINE; GLUCOSE; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

MUS;

EID: 84875228139     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1198-8     Document Type: Article

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