α-Selective glycosylation affords mucin-related GalNAc amino acids and diketopiperazines active on Trypanosoma cruzi

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 7, 2013, Pages 1978-1987

  Martins Teixeira, Maristela B ^a   Campo, Vanessa L ^a   Biondo, Monica ^a   Sesti Costa, Renata ^a   Carneiro, Zumira A ^a   Silva, João S ^a   Carvalho, Ivone ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Glycosyl diketopiperazine; Glycosylation; Mucin; trans Sialidase; Trypanosoma cruzi

Indexed keywords

2 ACETAMIDO 2 DEOXY ALPHA DELTA GALACTOPYRANOSYL SERINE; 2 ACETAMIDO 2 DEOXY ALPHA DELTA GALACTOPYRANOSYL THREONINE; AMINO ACID; ANTITRYPANOSOMAL AGENT; ASPARTIL O (2 ACETAMIDO 2 DEOXY ALPHA DELTA GALACTOPYRANOSYL)LEVO TREONYL; BENZNIDAZOLE; MUCIN; N (FLUOREN 9 YLMETHOXYCARBONYL) (2 ACETAMIDO 2 DEOXY 3,4,6, TRI O ACETYL ALPHA DELTA GALACTOPYRANOSYL)THREONINE BENZYL ESTER 9; N (FLUOREN 9 YLMETHOXYCARBONYL) (2 ACETAMIDO DEOXY 3,4,6, TRI O ACETYL ALPHA DELTA GALACTOPYRANOSYL)SERINE BENZYL ESTER 9; N (FLUOREN 9 YLMETHOXYCARBONYL) (2 AZIDO 2 DEOXY 3,4,6, TRI O ACETYL ALPHA DELTA GALACTOPYRANOSYL) SERINE BENZYL ESTER 9; N (FLUOREN 9 YLMETHOXYCARBONYL) (2 AZIDO 2 DEOXY 3,4,6, TRI O ACETYL ALPHA DELTA GALACTOPYRANOSYL)THREONINE BENZYL ESTER 9; N (FLUOREN 9 YLMETHOXYCARBONYL) (2 AZIDO 2 DEOXY 3,4,6, TRI O ACETYL BETA DELTA GALACTOPYRANOSYL) SERINE BENZYL ESTER 9; N [(9H FLUOREN 9 YLMETHOXY)CARBONYL] ASPARTIL O (2 ACETAMIDO 3,4,6 TRI O ACETYL 2 DEOXY ALPHA DELTA GALACTOPYRANOSYL) LEVO SERINE BENZYL ESTER; N [(9H FLUOREN 9 YLMETHOXY)CARBONYL] ASPARTIL O (2 ACETAMIDO 3,4,6 TRI O ACETYL 2 DEOXY ALPHA DELTA GALACTOPYRANOSYL) LEVO THREONINE BENZYL ESTER; NIFURTIMOX; PIPERAZINEDIONE; PIPERIDINE; SERINE; SIALIDASE; SIALIDASE INHIBITOR; THREONINE; UNCLASSIFIED DRUG;

AMASTIGOTE; ARTICLE; CATALYSIS; CROSS COUPLING REACTION; CYCLIZATION; DRUG STRUCTURE; GLYCOSYLATION; IC 50; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

ACETYLGALACTOSAMINE; ANIMALS; CELL LINE; CELLS, CULTURED; CHAGAS DISEASE; DIKETOPIPERAZINES; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; MICE; MICE, INBRED C57BL; MUCINS; NEURAMINIDASE; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 84875211228     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.01.027     Document Type: Article

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