Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 4, 2010, Pages 1633-1640

  Arioka, Shingo ^a,c   Sakagami, Masahiro ^c   Uematsu, Rie ^a   Yamaguchi, Hiroto ^c   Togame, Hiroko ^c   Takemoto, Hiroshi ^c   Hinou, Hiroshi ^a   Nishimura, Shin Ichiro ^a,b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c SHIONOGI AND CO LTD   (Japan)

Author keywords

Chagas' disease; Inhibitors; Natural product library; Trypanosoma cruzi trans sialidase

Indexed keywords

6 CHLORO 9,10 DIHYDRO 4,5,7 TRIHYDROXY 9,10 DIOXO 2 ANTHRACENECARBOXYLIC ACID; ANTHRAQUINONE DERIVATIVE; ANTIPROTOZOAL AGENT; FLAVAN 3 OL; FLAVAN DERIVATIVE; FLAVANOID; FLAVANONE; FLAVONE; FLAVONOL; ISOFLAVONE; MYRICETIN; SIALIDASE; SIALIDASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SPECIFICITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME SPECIFICITY; IC 50; LIGHT SCATTERING; NONHUMAN; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI;

BASE SEQUENCE; DNA PRIMERS; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GLYCOPROTEINS; NEURAMINIDASE; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA CRUZI;

PROTOZOA; TRYPANOSOMA CRUZI;

EID: 76049093946     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.12.062     Document Type: Article

References (38)

1. Tanowitz H.B., Kirchhoff L.V., Simon D., Morris S.A., Weiss L.M., and Wittner M. Clin. Microbiol. Rev. 5 (1992) 400
2. World Health Organization Control Of Chagas disease Tech. Rep. Ser. 2002, 905, 1.
3. Urbina J.A., and Docampo R. Trends Parasitol. 19 (2003) 495
4. Brener Z. Pharmacol. Ther. 7 (1979) 71
5. Schmuñis G.A., Szarfman A., Coarasa L., Guilleron C., and Peralta J.M. Am. J. Trop. Med. Hyg. 29 (1980) 170
6. de Castro S.L. Acta Trop. 53 (1993) 83
7. Neres J., Bryce R.A., and Douglas K.T. Drug Discovery Today 13 (2008) 110
8. Nishimura S.-I., Lee K.B., Matsuoka K., and Lee Y.C. Biochem. Biophys. Res. Commun. 199 (1994) 249
9. Previato J.O., Andrade A.F., Pessolani M.C., and Mendonça-Previato L. Mol. Biochem. Parasitol. 16 (1985) 85
10. Vandekerckhove F., Schenkman S., Pontes de Carvalho L., Tomlinson S., Kiso M., Yoshida M., Hasegawa A., and Nussenzweig V. Glycobiology 2 (1992) 541
11. Schenkman S., and Eichinger D. Parasitol. Today 9 (1993) 218
12. Tomlinson S., and Raper J. Parasitol. Today 14 (1998) 354
13. Pereira M.E., Zhang K., Gong Y., Herrera E.M., and Ming M. Infect. Immun. 64 (1996) 3884
14. Paris G., Ratier L., Amaya M.F., Nguyen T., Alzari P.M., and Frasch A.C. J. Mol. Biol. 345 (2005) 923
15. Verdine G.L. Nature 384 (1996) 11
16. Feher M., and Schmidt J.M. J. Chem. Inf. Comput. Sci. 43 (2003) 218
17. Harrigan G.G., and Goetz G.H. Comb. Chem. High Throughput Screen. 8 (2005) 529
18. Newman D.J., Cragg G.M., and Snader K.M. J. Nat. Prod. 66 (2003) 1022
19. Colman P.M., and Smith B.J. Structure 10 (2002) 1466
20. Ryan A.J., Gray N.M., Lowe P.N., and Chung C.W. J. Med. Chem. 46 (2003) 3448
21. Feng B.Y., and Shoichet B.K. Nat. Protocol 1 (2006) 550
22. Lipinski C.A., Lombardo F., Dominy B.W., and Feeney P.J. Adv. Drug Delivery Rev. 46 (2001) 3
23. Coan K.E., Maltby D.A., Burlingame A.L., and Shoichet B.K. J. Med. Chem. 52 (2009) 2067
24. Feng B.Y., Shelat A., Doman T.N., Guy R.K., and Shoichet B.K. Nat. Chem. Biol. 1 (2005) 146
25. Hata K., Koseki K., Yamaguchi K., Moriya S., Suzuki Y., Yingsakmongkon S., Hirai G., Sodeoka M., von Itzstein M., and Miyagi T. Antimicrob. Agents Chemother. 52 (2008) 3484
26. Schinor E.C., Salvador M.J., Ito I.Y., de Albuquerque S., and Dias D.A. Phytomedicine 11 (2004) 224
27. Kim J.H., Ryu H.W., Shim J.H., Park K.H., and Withers S.G. ChemBioChem 10 (2009) 2475
28. Buschiazzo A., Amaya M.F., Cremona M.L., Frasch A.C., and Alzari P.M. Mol. Cell 10 (2002) 757
29. Kuntz S., Wenzel U., and Daniel H. Eur. J. Nutr. 38 (1999) 133
30. Huang H.-S., Chen T.-C., Chen R.-H., Huang K.-F., Huang F.-C., Jhan J.-R., Chen C.-L., Lee C.-C., Lo Y., and Lin J.-J. Bioorg. Med. Chem. 17 (2009) 7418
31. Schenkman S., Chaves L.B., Pontes de Carvalho L.C., and Eichinger D. J. Biol. Chem. 269 (1994) 7970
32. El-Sayed, N. M.; Myler, P. J.; Bartholomeu, D. C.; Nilsson, D.; Aggarwal, G.; Tran, A. N.; Ghedin, E.; Worthey, E. A.; Delcher, A. L.; Blandin, G.; Westenberger, S. J.; Caler, E.; Cerqueira, G. C.; Branche, C.; Haas, B.; Anupama, A.; Arner, E.; Åslund, L.; Attipoe, P.; Bontempi, E.; Bringaud, F.; Burton, P.; Cadag, E.; Campbell, D. A.; Carrington, M.; Crabtree, J.; Darban, H.; da Silveira, J. F.; de Jong, P.; Edwards, K.; Englund, P. T.; Fazelina, G.; Feldblyum, T.; Ferella, M.; Frasch, A. C.; Gull, K.; Horn, D.; Hou, L.; Huang, Y.; Kindlund, E.; Klingbeil, M.; Kluge, S.; Koo, H.; Lacerda, D.; Levin, M. J.; Lorenzi, H.; Louie, T.; Machado, C. R.; McCulloch, R.; McKenna, A.; Mizuno, Y.; Mottram, J. C.; Nelson, S.; Ochaya, S.; Osoegawa, K.; Pai, G.; Parsons, M.; Pentony, M.; Pettersson, U.; Pop, M.; Ramirez, J. L.; Rinta, J.; Robertson, L.; Salzberg, S. L.; Sanchez, D. O.; Seyler, A.; Sharma, R.; Shetty, J.; Simpson, A. J.; Sisk, E.; Tammi, M. T.; Tarleton, R.; Teixeira, S.; Van Aken, S.; Vogt, C.; Ward, P.N.; Wickstead, B.; Wortman, J.; White, O.; Fraser, C.M.; Stuart, K.D.; Andersson, B. Science 2005, 309, 409.
33. Ribeirão M., Pereira-Chioccola V.L., Eichinger D., Rodrigues M.M., and Schenkman S. Glycobiology 7 (1997) 1237
34. Xiong A.S., Yao Q.H., Peng R.H., Li X., Fan H.Q., Cheng Z.M., and Li Y. Nucleic Acids Res. 32 (2004) e98
35. Xiong A.S., Yao Q.H., Peng R.H., Duan H., Li X., Fan H.Q., Cheng Z.M., and Li Y. Nat. Protocol 1 (2006) 791
36. In: Joseph Sambrook D.W.R. (Ed). Molecular Cloning: A Laboratory Manual. 3rd ed. Vols. 1-3 (2001), Cold Spring Harbor Laboratory Press, New York 1-999
37. Shapiro A.B., Walkup G.K., and Keating T.A. J. Biomol. Screen. 14 (2009) 1008
38. Zhang J.H., Chung T.D., and Oldenburg K.R. J. Biomol. Screen. 4 (1999) 67