Xiang-Qi-Tang and its active components exhibit anti-inflammatory and anticoagulant properties by inhibiting MAPK and NF-κB signaling pathways in LPS-treated rat cardiac microvascular endothelial cells

Immunopharmacology and Immunotoxicology

Volumn 35, Issue 2, 2013, Pages 215-224

  He, Chang Liang ^a,b   Yi, Peng Fei ^b   Fan, Qiao Jia ^a   Shen, Hai Qing ^b   Jiang, Xiao Lin ^a   Qin, Qian Qian ^b   Song, Zhou ^b   Zhang, Cui ^b   Wu, Shuai Cheng ^b   Wei, Xu Bin ^b   Li, Ying Lun ^a   Fu, Ben Dong ^b  

^a SICHUAN AGRICULTURAL UNIVERSITY   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

Coagulation; Endothelial cell; Inflammation; Traditional Chinese medicine; Xiang Qi Tang

Indexed keywords

ALPHA CYPERONE; ANDROGRAPHOLIDE; ANTICOAGULANT AGENT; ANTIINFLAMMATORY AGENT; ASTRAGALOSIDE IV; CHINESE DRUG; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; KRUPPEL LIKE FACTOR 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT MEDICINAL PRODUCT; PLASMINOGEN ACTIVATOR INHIBITOR 1; STRESS ACTIVATED PROTEIN KINASE; THROMBOPLASTIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XIANG QI TANG; HERBACEOUS AGENT; KRUPPEL LIKE FACTOR; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANTICOAGULATION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEART MUSCLE CELL; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENDOTHELIUM CELL; HEART; INFLAMMATION; METABOLISM; MICROVASCULATURE; PHOSPHORYLATION; VASCULAR ENDOTHELIUM; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTICOAGULANTS; DRUGS, CHINESE HERBAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEART; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LIPOPOLYSACCHARIDES; MICROVESSELS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; THROMBOPLASTIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84875011300     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2012.744034     Document Type: Article

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