Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia

Blood

Volumn 101, Issue 11, 2003, Pages 4446-4448

  Branger, Judith ^a   Van den Blink, Bernt ^b   Weijer, Sebastiaan ^b   Gupta, Abhya ^b   Van Deventer, Sander J H ^b   Hack, C Erik ^b   Peppelenbosch, Maikel P ^b   Van der Poll, Tom ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ANTIPLASMIN; BIRB 796 BS; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PLACEBO; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROCOAGULANT; PROTHROMBIN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; BIOLOGICAL MARKER; DORAMAPIMOD; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NAPHTHALENE DERIVATIVE; PYRAZOLE DERIVATIVE;

ANTICOAGULATION; ARTICLE; BLOOD CLOTTING; CELL ACTIVATION; DOSE RESPONSE; ENDOTHELIUM CELL; ENDOTOXEMIA; FIBRINOLYSIS; HUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; ADULT; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOLOGY; DOUBLE BLIND PROCEDURE; DRUG ANTAGONISM; DRUG EFFECT; MALE; METABOLISM; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; VASCULAR ENDOTHELIUM;

ADULT; BIOLOGICAL MARKERS; BLOOD COAGULATION; DOUBLE-BLIND METHOD; ENDOTHELIUM, VASCULAR; ENDOTOXEMIA; ENZYME INHIBITORS; FIBRINOLYSIS; HUMANS; LIPOPOLYSACCHARIDES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NAPHTHALENES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRAZOLES;

EID: 0037804774     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-11-3338     Document Type: Article

References (24)

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