Anti-inflammatory effects of Polygala tenuifolia root through inhibition of NF-κB activation in lipopolysaccharide-induced BV2 microglial cells

Journal of Ethnopharmacology

Volumn 137, Issue 3, 2011, Pages 1402-1408

  Cheong, Myung Hee ^a   Lee, Sang Ryong ^a   Yoo, Hwa Seung ^a   Jeong, Jin Woo ^b,c   Kim, Gi Young ^d   Kim, Wun Jae ^e   Jung, In Chul ^a   Choi, Yung Hyun ^c  

^a Daejeon University   (South Korea)

^b Pusan National University   (South Korea)

^c Dong Eui University   (South Korea)

^d Jeju National University   (South Korea)

^e Chungbuk National University College of Medicine   (South Korea)

Author keywords

Cytokines; NF B; NO; PGE 2; Polygala tenuifolia

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MYELOID DIFFERENTIATION FACTOR 88; NITRIC OXIDE; PLANT EXTRACT; POLYGALA TENUIFOLIA EXTRACT; PROSTAGLANDIN E2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; INHIBITION KINETICS; MEDICINAL PLANT; MICROGLIA; NONHUMAN; PLANT ROOT; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; I-KAPPA B PROTEINS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PLANT ROOTS; PLANTS, MEDICINAL; POLYGALA; RNA, MESSENGER; SOLVENTS; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; WATER;

MURINAE; POLYGALA TENUIFOLIA;

EID: 80054909414     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.08.008     Document Type: Article

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