Corosolic acid induces apoptotic cell death in human lung adenocarcinoma A549 cells in vitro

Food and Chemical Toxicology

Volumn 56, Issue , 2013, Pages 8-17

  Nho, Kyoung Jin ^a   Chun, Jin Mi ^a   Kim, Ho Kyoung ^a  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

A549 cells; Apoptosis; Caspase; Corosolic acid; Mitochondria; Reactive oxygen species

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; COROSOLIC ACID; CYTOCHROME C; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL XL; PROTEIN BID; REACTIVE OXYGEN METABOLITE; SURVIVIN; TRITERPENOID; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LUNG ADENOCARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; OLIGOPEPTIDES; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; TRITERPENES;

EID: 84874755036     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.02.002     Document Type: Article

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