Corosolic acid triggers mitochondria and caspase-dependent apoptotic cell death in osteosarcoma MG-63 cells

Phytotherapy Research

Volumn 25, Issue 9, 2011, Pages 1354-1361

  Cai, Xiaobing ^a   Zhang, Hao ^b   Tong, Dake ^b   Tan, Zhangyong ^b   Han, Dong ^b   Ji, Fang ^b   Hu, Wei ^b  

^a TENTH PEOPLE S HOSPITAL OF TONGJI UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; caspase; corosolic acid; mitochondria; osteosarcoma

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; COROSOLIC ACID; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL 2; TRITERPENOID; UNCLASSIFIED DRUG; BAX PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; TRITERPENE;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OSTEOSARCOMA; PROTEIN EXPRESSION; UPREGULATION; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OSTEOSARCOMA; TRITERPENES;

EID: 79957801142     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3422     Document Type: Article

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