메뉴 건너뛰기




Volumn 114, Issue 1, 2005, Pages 1-11

Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells

Author keywords

m; Apoptosis; Bax Bcl2; Caspases; M4Beu; Mitochondria; Ursolic acid

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS INDUCING FACTOR; PROTEIN BAX; PROTEIN BCL 2; TRITERPENE DERIVATIVE; URSOLIC ACID;

EID: 13244255330     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20588     Document Type: Article
Times cited : (149)

References (54)
  • 3
    • 0023948263 scopus 로고
    • Patterns of invasive melanoma in the Connecticut tumor registry: Is the long-term increase real?
    • Roush GC, Schymura MJ, Holdford TR. Patterns of invasive melanoma in the Connecticut tumor registry: is the long-term increase real? Cancer 1988;61:2586-95.
    • (1988) Cancer , vol.61 , pp. 2586-2595
    • Roush, G.C.1    Schymura, M.J.2    Holdford, T.R.3
  • 4
    • 0031819345 scopus 로고    scopus 로고
    • Semiological value of ABCDE criteria in the diagnosis of cutaneous pigmented tumors
    • Thomas L, Tranchand P, Berard F, Secchi T, Colin C, Moulin G. Semiological value of ABCDE criteria in the diagnosis of cutaneous pigmented tumors. Dermatology 1998;197:11-7.
    • (1998) Dermatology , vol.197 , pp. 11-17
    • Thomas, L.1    Tranchand, P.2    Berard, F.3    Secchi, T.4    Colin, C.5    Moulin, G.6
  • 7
    • 0029567968 scopus 로고
    • Pharmacology of oleanolic acid and ursolic acid
    • Liu J. Pharmacology of oleanolic acid and ursolic acid. J Ethnopharmacol 1995;49:57-68.
    • (1995) J Ethnopharmacol , vol.49 , pp. 57-68
    • Liu, J.1
  • 8
    • 0030002548 scopus 로고    scopus 로고
    • Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibrosarcoma cells
    • Cha HJ, Bae SK, Lee HY, Lee OH, Sato H, Seiki M, Park BC, Kim KW. Anti-invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase-9 (MMP-9) in HT1080 human fibrosarcoma cells. Cancer Res 1996;56:2281-4.
    • (1996) Cancer Res , vol.56 , pp. 2281-2284
    • Cha, H.J.1    Bae, S.K.2    Lee, H.Y.3    Lee, O.H.4    Sato, H.5    Seiki, M.6    Park, B.C.7    Kim, K.W.8
  • 9
    • 0035717684 scopus 로고    scopus 로고
    • Liposome-encapsulated ursolic acid increases ceramides and collagen in human skin cells
    • Both DM, Goodtzova K, Yarosh DB, Brown DA. Liposome-encapsulated ursolic acid increases ceramides and collagen in human skin cells. Arch Dermatol Res 2002;293:569-75.
    • (2002) Arch Dermatol Res , vol.293 , pp. 569-575
    • Both, D.M.1    Goodtzova, K.2    Yarosh, D.B.3    Brown, D.A.4
  • 10
    • 0034583325 scopus 로고    scopus 로고
    • Liposomal ursolic acid (merotaine) increases ceramides and collagen in human skin
    • Yarosh DB, Both D, Brown D. Liposomal ursolic acid (merotaine) increases ceramides and collagen in human skin. Horm Res 2000;54:318-21.
    • (2000) Horm Res , vol.54 , pp. 318-321
    • Yarosh, D.B.1    Both, D.2    Brown, D.3
  • 12
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H. Mechanisms and genes of cellular suicide. Science 1995;267:1445-9.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 13
    • 0032544268 scopus 로고    scopus 로고
    • Apoptotic pathways: The roads to ruin
    • Green DR. Apoptotic pathways: the roads to ruin. Cell 1998;94:695-8.
    • (1998) Cell , vol.94 , pp. 695-698
    • Green, D.R.1
  • 15
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshaw WC, Martins LM, Kaufmann SH. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 1999;68:383-424.
    • (1999) Annu Rev Biochem , vol.68 , pp. 383-424
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 16
    • 0037021415 scopus 로고    scopus 로고
    • A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis
    • Gupta S, Radha V, Sudhakar Ch, Swarup G. A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis. FEES Lett 2002;532:61-6.
    • (2002) FEES Lett , vol.532 , pp. 61-66
    • Gupta, S.1    Radha, V.2    Sudhakar, Ch.3    Swarup, G.4
  • 17
    • 0031731989 scopus 로고    scopus 로고
    • Genetics of programmed cell death in C. elegans: Past, present and future
    • Metzstein MM, Stanfield GM, Horvitz HR. Genetics of programmed cell death in C. elegans: past, present and future. Trends Genet 1998;14:410-6.
    • (1998) Trends Genet , vol.14 , pp. 410-416
    • Metzstein, M.M.1    Stanfield, G.M.2    Horvitz, H.R.3
  • 18
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO. The biochemistry of apoptosis. Nature 2000;407:770-6.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 19
    • 0034641980 scopus 로고    scopus 로고
    • Apoptosis in development
    • Meier P, Finch A, Evan G. Apoptosis in development. Nature 2000;407:796-801.
    • (2000) Nature , vol.407 , pp. 796-801
    • Meier, P.1    Finch, A.2    Evan, G.3
  • 20
  • 24
    • 0033452740 scopus 로고    scopus 로고
    • Bcl-X(S)-induced cell death in 3T3 cells does not require or induce caspase activation
    • Fridman JS, Benedict MA, Maybaum J. Bcl-X(S)-induced cell death in 3T3 cells does not require or induce caspase activation. Cancer Res 1999;59:5999-6004.
    • (1999) Cancer Res , vol.59 , pp. 5999-6004
    • Fridman, J.S.1    Benedict, M.A.2    Maybaum, J.3
  • 26
    • 0030613630 scopus 로고    scopus 로고
    • Enhancement by O6-benzyl-N2-acetylguanosine of N′-[2-chloroethyl]- N-[2-(methylsulphonyl)ethyl]-N′-nitrosourea therapeutic index on nude mice bearing resistant human melanoma
    • Debiton E, Cussac-Buchdhal C, Mounetou E, Rapp M, Dupuy JM, Maurizis JC, Veyre A, Madelmont JC. Enhancement by O6-benzyl-N2-acetylguanosine of N′-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N′-nitrosourea therapeutic index on nude mice bearing resistant human melanoma. Br J Cancer 1997;7:1157-62.
    • (1997) Br J Cancer , vol.7 , pp. 1157-1162
    • Debiton, E.1    Cussac-Buchdhal, C.2    Mounetou, E.3    Rapp, M.4    Dupuy, J.M.5    Maurizis, J.C.6    Veyre, A.7    Madelmont, J.C.8
  • 27
    • 0028323448 scopus 로고
    • Two human melanoma cell-line variants with enhanced in vivo tumor growth and metastatic capacity do not express the beta 3 integrin subunit
    • Boukerche H, Benchaibi M, Berthier-Vergnes O, Lizard G, Bailly M, Bailly M, McGregor JL. Two human melanoma cell-line variants with enhanced in vivo tumor growth and metastatic capacity do not express the beta 3 integrin subunit. Eur J Biochem 1994;220:485-91.
    • (1994) Eur J Biochem , vol.220 , pp. 485-491
    • Boukerche, H.1    Benchaibi, M.2    Berthier-Vergnes, O.3    Lizard, G.4    Bailly, M.5    Bailly, M.6    McGregor, J.L.7
  • 28
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 29
    • 0036015503 scopus 로고    scopus 로고
    • Visna virus-induced cytopathic effect in vitro is caused by apoptosis
    • Duval R, Delebassée S, Cardot PJ, Bosgiraud C. Visna virus-induced cytopathic effect in vitro is caused by apoptosis. Arch Virol 2002;147:943-59.
    • (2002) Arch Virol , vol.147 , pp. 943-959
    • Duval, R.1    Delebassée, S.2    Cardot, P.J.3    Bosgiraud, C.4
  • 30
    • 0036936398 scopus 로고    scopus 로고
    • Implication of caspases during maedi-visna virus-induced apoptosis
    • Duval R, Bellet V, Delebassee S, Bosgiraud C. Implication of caspases during maedi-visna virus-induced apoptosis. J Gen Virol 2002;83:3153-61.
    • (2002) J Gen Virol , vol.83 , pp. 3153-3161
    • Duval, R.1    Bellet, V.2    Delebassee, S.3    Bosgiraud, C.4
  • 31
    • 0348112521 scopus 로고    scopus 로고
    • Sensitive and reliable JC-1 and TOTO-3 double staining to assess mitochondrial transmembrane potential and plasma membrane integrity: Interest for cell death investigations
    • Zuliani T, Duval R, Jayat C, Schnebert S, Andre P, Dumas M, Ratinaud MH. Sensitive and reliable JC-1 and TOTO-3 double staining to assess mitochondrial transmembrane potential and plasma membrane integrity: interest for cell death investigations. Cytometry 2003;54:100-8.
    • (2003) Cytometry , vol.54 , pp. 100-108
    • Zuliani, T.1    Duval, R.2    Jayat, C.3    Schnebert, S.4    Andre, P.5    Dumas, M.6    Ratinaud, M.H.7
  • 35
    • 0042530176 scopus 로고    scopus 로고
    • Ursolic acid inhibits proliferation and stimulates apoptosis in HT29 cells following activation of alkaline sphingomyelinase
    • Andersson D, Liu JJ, Nilsson A, Duan RD. Ursolic acid inhibits proliferation and stimulates apoptosis in HT29 cells following activation of alkaline sphingomyelinase. Anticancer Res 2003;23:3317-22.
    • (2003) Anticancer Res , vol.23 , pp. 3317-3322
    • Andersson, D.1    Liu, J.J.2    Nilsson, A.3    Duan, R.D.4
  • 36
    • 0029960889 scopus 로고    scopus 로고
    • MCF-7 cell cycle arrested at G1 through ursolic acid, and increased reduction of tetrazolium salts
    • Es-Saady D, Simon A, Jayat-Vignoles C, Chulia AJ, Delage C. MCF-7 cell cycle arrested at G1 through ursolic acid, and increased reduction of tetrazolium salts. Anticancer Res 1996;16:481-6.
    • (1996) Anticancer Res , vol.16 , pp. 481-486
    • Es-Saady, D.1    Simon, A.2    Jayat-Vignoles, C.3    Chulia, A.J.4    Delage, C.5
  • 37
    • 0035157543 scopus 로고    scopus 로고
    • Ursolic acid-induced changes in tumor growth, O2 consumption, and tumor interstitial fluid pressure
    • Lee I, Lee J, Lee YH, Leonard J. Ursolic acid-induced changes in tumor growth, O2 consumption, and tumor interstitial fluid pressure. Anticancer Res 2001;21:2827-33.
    • (2001) Anticancer Res , vol.21 , pp. 2827-2833
    • Lee, I.1    Lee, J.2    Lee, Y.H.3    Leonard, J.4
  • 38
    • 0027179465 scopus 로고
    • Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: A further pitfall in the use of the MTT assay for evaluating cell growth and survival
    • Pagliacci MC, Spinozzi F, Migliorati G, Fumi G, Smacchia M, Grignani F, Riccardi C, Nicoletti I. Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival. Eur J Cancer 1993;29:1573-7.
    • (1993) Eur J Cancer , vol.29 , pp. 1573-1577
    • Pagliacci, M.C.1    Spinozzi, F.2    Migliorati, G.3    Fumi, G.4    Smacchia, M.5    Grignani, F.6    Riccardi, C.7    Nicoletti, I.8
  • 39
    • 0034477152 scopus 로고    scopus 로고
    • Cytostatic, cytotoxic and protein tyrosine kinase inhibitory activity of ursolic acid in A431 human tumor cells
    • Hollosy F, Meszaros G, Bokonyi G, Idei M, Seprodi A, Szende B, Keri G. Cytostatic, cytotoxic and protein tyrosine kinase inhibitory activity of ursolic acid in A431 human tumor cells. Anticancer Res 2000;20:4563-70.
    • (2000) Anticancer Res , vol.20 , pp. 4563-4570
    • Hollosy, F.1    Meszaros, G.2    Bokonyi, G.3    Idei, M.4    Seprodi, A.5    Szende, B.6    Keri, G.7
  • 40
    • 0034664936 scopus 로고    scopus 로고
    • Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase
    • Mizushina Y, Iida A, Ohta K, Sugawara F, Sakaguchi K. Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase. Biochem J 2000;350:757-63.
    • (2000) Biochem J , vol.350 , pp. 757-763
    • Mizushina, Y.1    Iida, A.2    Ohta, K.3    Sugawara, F.4    Sakaguchi, K.5
  • 43
    • 0035989085 scopus 로고    scopus 로고
    • Ex vivo apoptotic potential of peripheral blood mononuclear cells of the elderly human subject
    • Szmit E, Trzonkowski P, Mysliwska J, Foester J, Mysliwski A. Ex vivo apoptotic potential of peripheral blood mononuclear cells of the elderly human subject. Cell Biol Int 2002;26:517-27.
    • (2002) Cell Biol Int , vol.26 , pp. 517-527
    • Szmit, E.1    Trzonkowski, P.2    Mysliwska, J.3    Foester, J.4    Mysliwski, A.5
  • 44
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-31.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 45
    • 0032901057 scopus 로고    scopus 로고
    • Activation of caspases and p53 by bovine herpesvirus 1 infection results in programmed cell death and efficient virus release
    • Devireddy L, Jones CJ. Activation of caspases and p53 by bovine herpesvirus 1 infection results in programmed cell death and efficient virus release. J Virol 1999;73:3778-88.
    • (1999) J Virol , vol.73 , pp. 3778-3788
    • Devireddy, L.1    Jones, C.J.2
  • 46
    • 0028821783 scopus 로고
    • Consequence of p53 gene expression by adenovirus vector on cell cycle arrest and apoptosis in human aortic vascular smooth muscle cells
    • Katayose D, Wersto R, Cowan K, Seth P. Consequence of p53 gene expression by adenovirus vector on cell cycle arrest and apoptosis in human aortic vascular smooth muscle cells. Biochem Biophys Res Commun 1995;215:446-51.
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 446-451
    • Katayose, D.1    Wersto, R.2    Cowan, K.3    Seth, P.4
  • 47
    • 0033162401 scopus 로고    scopus 로고
    • Involvement of heat-shock protein 70 and p53 proteins in attenuation of UVC-induced apoptosis by thermal stress in hepatocellular carcinoma cells
    • Chen YC, Lin-Shiau SY, Lin JK. Involvement of heat-shock protein 70 and p53 proteins in attenuation of UVC-induced apoptosis by thermal stress in hepatocellular carcinoma cells. Photochem Photobiol 1999;70:78-86.
    • (1999) Photochem Photobiol , vol.70 , pp. 78-86
    • Chen, Y.C.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 48
    • 0036478938 scopus 로고    scopus 로고
    • Introduction: Mitochondrial control of apoptosis
    • Kroemer G. Introduction: mitochondrial control of apoptosis. Biochimie 2002;84:103-4.
    • (2002) Biochimie , vol.84 , pp. 103-104
    • Kroemer, G.1
  • 50
    • 0037164865 scopus 로고    scopus 로고
    • Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli
    • Arnoult D, Parone P, Martinou JC, Antonsson B, Estaquier J, Ameinsen JC. Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli. J Cell Biol 2002;159:923-9.
    • (2002) J Cell Biol , vol.159 , pp. 923-929
    • Arnoult, D.1    Parone, P.2    Martinou, J.C.3    Antonsson, B.4    Estaquier, J.5    Ameinsen, J.C.6
  • 51
    • 0042237031 scopus 로고    scopus 로고
    • Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization
    • Arnoult D, Gaume B, Karbowski M, Sharpe JC, Cecconi F, Youle RJ. Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization. EMBO J 2003;22:4385-99.
    • (2003) EMBO J , vol.22 , pp. 4385-4399
    • Arnoult, D.1    Gaume, B.2    Karbowski, M.3    Sharpe, J.C.4    Cecconi, F.5    Youle, R.J.6
  • 52
    • 1542600200 scopus 로고    scopus 로고
    • Heat shock protein 70 neutralizes apoptosis-inducing factor
    • Kroemer G. Heat shock protein 70 neutralizes apoptosis-inducing factor. Sci World J 2001;1:590-2.
    • (2001) Sci World J , vol.1 , pp. 590-592
    • Kroemer, G.1
  • 54
    • 0038492656 scopus 로고    scopus 로고
    • Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase activation
    • Tan Y, Yu R, Pezzuto JM. Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase activation. Clin Cancer Res 2003;9:2866-75.
    • (2003) Clin Cancer Res , vol.9 , pp. 2866-2875
    • Tan, Y.1    Yu, R.2    Pezzuto, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.