CCN2/CTGF increases expression of miR-302 micrornas, which target the TGFβ type II receptor with implications for nephropathic cell phenotypes

Journal of Cell Science

Volumn 125, Issue 23, 2012, Pages 5621-5629

  Faherty, Noel ^a   Curran, Simon P ^a   O'Donovan, Helen ^a   Martin, Finian ^a   Godson, Catherine ^a   Brazil, Derek P ^b   Crean, John K ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

CCN2 CTGF; MicroRNA; Nephropathy; TGF

Indexed keywords

COMPLEMENTARY DNA; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; MICRORNA; MICRORNA 302; THROMBOSPONDIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; URETER OBSTRUCTION;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CONNECTIVE TISSUE GROWTH FACTOR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MALE; MESANGIAL CELLS; MICE; MICE, INBRED C57BL; MICRORNAS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84874708151     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.105528     Document Type: Article

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