Copper induced immunotoxicity promote differential apoptotic pathways in spleen and thymus

Toxicology

Volumn 306, Issue , 2013, Pages 74-84

  Mitra, Soham ^a   Keswani, Tarun ^a   Ghosh, Nabanita ^a   Goswami, Suranjana ^a   Datta, Anuradha ^a   Das, Salomie ^a   Maity, Subhajit ^a   Bhattacharyya, Arindam ^a  

^a UNIVERSITY OF CALCUTTA   (India)

Author keywords

Apoptosis; CD4+ T cell; CD8+ T cell; Copper; P53; ROS; Spleen; Thymus

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; COPPER; CUPRIC ION; CYCLOOXYGENASE 2; CYTOCHROME C; DEATH RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CYCLE ARREST; CELL LYSATE; CONTROLLED STUDY; IMMUNE DEFICIENCY; IMMUNOHISTOCHEMISTRY; IMMUNOTOXICITY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SPLEEN; SPLEEN CELL; THYMOCYTE; THYMUS;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; COPPER; MICE; RANDOM ALLOCATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SPLEEN; THYMUS GLAND; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84874672854     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.01.001     Document Type: Article

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