Copper-induced immunotoxicity involves cell cycle arrest and cell death in the spleen and thymus

Toxicology

Volumn 293, Issue 1-3, 2012, Pages 78-88

  Mitra, Soham ^a   Keswani, Tarun ^a   Dey, Manali ^a   Bhattacharya, Shaswati ^a   Sarkar, Samrat ^a   Goswami, Suranjana ^a   Ghosh, Nabanita ^a   Dutta, Anuradha ^a   Bhattacharyya, Arindam ^a  

^a UNIVERSITY OF CALCUTTA   (India)

Author keywords

Bax; Copper; EndoG; Immunotoxicity; Spleen; Thymus; Ubiquitin

Indexed keywords

COPPER CHLORIDE; LIPOCORTIN 5; PROTEIN BAX;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL ASSAY; CELL COUNT; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL FUNCTION; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNE SYSTEM; IMMUNOHISTOCHEMISTRY; IMMUNOTOXICITY; MORPHOMETRICS; MOUSE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN; SPLEEN CELL; THYMOCYTE; THYMUS; THYMUS ATROPHY; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; ATROPHY; BCL-2-ASSOCIATED X PROTEIN; CELL COUNT; CELL CYCLE CHECKPOINTS; CELL DEATH; CELLS, CULTURED; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDODEOXYRIBONUCLEASES; IMMUNOSUPPRESSIVE AGENTS; INJECTIONS, INTRAPERITONEAL; LETHAL DOSE 50; MICE; ORGAN SIZE; RANDOM ALLOCATION; SPLEEN; THYMUS GLAND; UBIQUITIN;

MUS;

EID: 84857064405     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.12.013     Document Type: Article

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