메뉴 건너뛰기




Volumn 20, Issue 13, 2000, Pages 4580-4590

Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN P21;

EID: 0034045930     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.13.4580-4590.2000     Document Type: Article
Times cited : (107)

References (53)
  • 1
    • 0028037048 scopus 로고
    • Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells
    • Ahmad, S., T. Mineta, R. L. Martuza, and R. I. Glazer. 1994. Antisense expression of protein kinase C alpha inhibits the growth and tumorigenicity of human glioblastoma cells. Neurosurgery 35:904-909.
    • (1994) Neurosurgery , vol.35 , pp. 904-909
    • Ahmad, S.1    Mineta, T.2    Martuza, R.L.3    Glazer, R.I.4
  • 2
    • 0032145348 scopus 로고    scopus 로고
    • Regulation of the cell cycle at the G2/M boundary in metastatic melanoma cells by 12-O-tetradecanoyl phorbol-13-acetate (TPA) by blocking p34cdc2 kinase activity
    • Arita, Y., P. Buffolino, and D. L. Coppock. 1998. Regulation of the cell cycle at the G2/M boundary in metastatic melanoma cells by 12-O-tetradecanoyl phorbol-13-acetate (TPA) by blocking p34cdc2 kinase activity. Exp. Cell Res. 242:381-390.
    • (1998) Exp. Cell Res. , vol.242 , pp. 381-390
    • Arita, Y.1    Buffolino, P.2    Coppock, D.L.3
  • 3
    • 0027185914 scopus 로고
    • High dose tamoxifen in the treatment of recurrent high-grade glioma: A report of clinical stabilization and tumor regression
    • Baltuch, G. H., G. Shenouda, A. Langleben, and J. H. Villemure. 1993. High dose tamoxifen in the treatment of recurrent high-grade glioma: a report of clinical stabilization and tumor regression. Can. J. Neurol. Sci. 20:168-170.
    • (1993) Can. J. Neurol. Sci. , vol.20 , pp. 168-170
    • Baltuch, G.H.1    Shenouda, G.2    Langleben, A.3    Villemure, J.H.4
  • 4
    • 0027496591 scopus 로고
    • Staurosporine differentially inhibits glioma versus non-glioma cell lines
    • Baltuch, G. H., N. P. Dooley, W. T. Couldwell, and V. W. Yong. 1993. Staurosporine differentially inhibits glioma versus non-glioma cell lines. J. Neurooncol. 16:141-147.
    • (1993) J. Neurooncol. , vol.16 , pp. 141-147
    • Baltuch, G.H.1    Dooley, N.P.2    Couldwell, W.T.3    Yong, V.W.4
  • 6
    • 8944239874 scopus 로고    scopus 로고
    • Inhibition of the growth of glioblastomas by CPG41251, an inhibitor of protein kinase C, and by phorbol ester tumor promoter
    • Begemann, M., S. A. Kashimawo, Y. J. A. Choi, et al. 1996. Inhibition of the growth of glioblastomas by CPG41251, an inhibitor of protein kinase C, and by phorbol ester tumor promoter. Clin. Cancer Res. 2:1017-1030.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 1017-1030
    • Begemann, M.1    Kashimawo, S.A.2    Choi, Y.J.A.3
  • 7
    • 0031906358 scopus 로고    scopus 로고
    • Molecular genetics correlates of p16, CDK4, and Rb immunochemistry in glioblastomas
    • Burns, K. L., K. Ueki, S. L. Jhung, J. Koh, and D. N. Louis. 1998. Molecular genetics correlates of p16, CDK4, and Rb immunochemistry in glioblastomas. J. Neuropathol. Exp. Neurol. 57:122-130.
    • (1998) J. Neuropathol. Exp. Neurol. , vol.57 , pp. 122-130
    • Burns, K.L.1    Ueki, K.2    Jhung, S.L.3    Koh, J.4    Louis, D.N.5
  • 8
    • 0033559264 scopus 로고    scopus 로고
    • The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
    • Cheng, M., P. Olivier, J. A. Dielh, M. Fero, M. F. Roussel, J. M. Roberts, and C. J. Sherr. 1999. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 18:1571-1583.
    • (1999) EMBO J. , vol.18 , pp. 1571-1583
    • Cheng, M.1    Olivier, P.2    Dielh, J.A.3    Fero, M.4    Roussel, M.F.5    Roberts, J.M.6    Sherr, C.J.7
  • 9
    • 0030982897 scopus 로고    scopus 로고
    • Cyclin dependent kinase 6 (CDK6) amplification in human gliomas identified using two-dimensional separation of genomic DNA
    • Costello, J. F., C. Plass, W. Arap, V. M. Chapman, W. A. Held, M. S. Berger, H. J. S. Huang, and W. K. Cavenee. 1997. Cyclin dependent kinase 6 (CDK6) amplification in human gliomas identified using two-dimensional separation of genomic DNA. Cancer Res. 57:1250-1254.
    • (1997) Cancer Res. , vol.57 , pp. 1250-1254
    • Costello, J.F.1    Plass, C.2    Arap, W.3    Chapman, V.M.4    Held, W.A.5    Berger, M.S.6    Huang, H.J.S.7    Cavenee, W.K.8
  • 10
    • 0026746408 scopus 로고
    • Protein kinase C activity correlates with the growth rate of malignant gliomas. II. Effect of glioma mitogens and modulators of PKC
    • Couldwell, W. T., J. P. Antel, and V. W. Yong. 1992. Protein kinase C activity correlates with the growth rate of malignant gliomas. II. Effect of glioma mitogens and modulators of PKC. Neurosurgery 31:717-724.
    • (1992) Neurosurgery , vol.31 , pp. 717-724
    • Couldwell, W.T.1    Antel, J.P.2    Yong, V.W.3
  • 13
    • 0028051952 scopus 로고
    • The protein kinase C activator, phorbol ester, cooperates with wild type p53 species in ras transformed embryo fibroblasts growth arrest
    • Delphin, C., and J. Baudier. 1994. The protein kinase C activator, phorbol ester, cooperates with wild type p53 species in ras transformed embryo fibroblasts growth arrest. J. Biol. Chem. 269:29579-29587.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29579-29587
    • Delphin, C.1    Baudier, J.2
  • 14
    • 0030728496 scopus 로고    scopus 로고
    • Cyclin and cyclin-dependent kinase expression in human astrocytoma cell lines
    • Dirks, P. B., S. L. Hubbard, M. Murakami, and J. T. Rutka. 1997. Cyclin and cyclin-dependent kinase expression in human astrocytoma cell lines. J. Neuropathol. Exp. Neurol. 56:291-300.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 291-300
    • Dirks, P.B.1    Hubbard, S.L.2    Murakami, M.3    Rutka, J.T.4
  • 15
    • 0032704902 scopus 로고    scopus 로고
    • The protein SET regulates the inhibitory effect of p21/Cip1 on cyclin-E-cyclin dependent kinase-2 activity
    • Estanyol, J. M., M. Jaumont, O. Casanovas, A. Rodriguez-Vilarrupla, N. Agell, and O. Bachs. 1999. The protein SET regulates the inhibitory effect of p21/Cip1 on cyclin-E-cyclin dependent kinase-2 activity. J. Biol. Chem. 274: 33161-33165.
    • (1999) J. Biol. Chem. , vol.274 , pp. 33161-33165
    • Estanyol, J.M.1    Jaumont, M.2    Casanovas, O.3    Rodriguez-Vilarrupla, A.4    Agell, N.5    Bachs, O.6
  • 16
    • 0031984081 scopus 로고    scopus 로고
    • The role of protein kinase C in G1 and G2/M phases of the cell cycle
    • Fishman, D. D., S. Segal, and E. Livneh. 1998. The role of protein kinase C in G1 and G2/M phases of the cell cycle. Int. J. Oncol. 12:181-186.
    • (1998) Int. J. Oncol. , vol.12 , pp. 181-186
    • Fishman, D.D.1    Segal, S.2    Livneh, E.3
  • 17
    • 0030946540 scopus 로고    scopus 로고
    • Protein kinase C mediated cell cycle arrest involves induction of p21Waf1/Cip1 and p27Kip1 and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells
    • Frey, M. R., M. L. Saxon, X. Zhao, A. Rollins, S. S. Evans, and J. D. Black. 1997. Protein kinase C mediated cell cycle arrest involves induction of p21Waf1/Cip1 and p27Kip1 and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells. J. Biol. Chem. 272:9424-9435.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9424-9435
    • Frey, M.R.1    Saxon, M.L.2    Zhao, X.3    Rollins, A.4    Evans, S.S.5    Black, J.D.6
  • 18
    • 0030827303 scopus 로고    scopus 로고
    • Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein
    • Funk, J. O., S. Waga, J. B. Harry, E. Espling, B. Stillman, and D. A. Galloway. 1997. Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes Dev. 11:2090-2100.
    • (1997) Genes Dev. , vol.11 , pp. 2090-2100
    • Funk, J.O.1    Waga, S.2    Harry, J.B.3    Espling, E.4    Stillman, B.5    Galloway, D.A.6
  • 19
    • 0030029622 scopus 로고
    • Protein kinase C inhibits the CAK-CDK2 cyclin dependent kinase cascade and G1/S cell cycle progression in human diploid fibroblasts
    • Hamada, K., N. Takuwa, W. Zhou, M. Kumada, and Y. Takuwa. 1993. Protein kinase C inhibits the CAK-CDK2 cyclin dependent kinase cascade and G1/S cell cycle progression in human diploid fibroblasts. Biochim. Biophys. Acta 1310:149-156.
    • (1993) Biochim. Biophys. Acta , vol.1310 , pp. 149-156
    • Hamada, K.1    Takuwa, N.2    Zhou, W.3    Kumada, M.4    Takuwa, Y.5
  • 20
    • 0027569091 scopus 로고
    • Phorbol ester induced monocytic differentiation is associated with G2 delay and down regulation of cdc25 expression
    • Hass, R., H. Gunji, M. Hirano, R. Weichselbaum, and D. Kufe. 1993. Phorbol ester induced monocytic differentiation is associated with G2 delay and down regulation of cdc25 expression. Cell Growth Differ. 4:159-156.
    • (1993) Cell Growth Differ. , vol.4 , pp. 159-1156
    • Hass, R.1    Gunji, H.2    Hirano, M.3    Weichselbaum, R.4    Kufe, D.5
  • 21
    • 0028970955 scopus 로고
    • Lack of p16INK4 or retinoblastoma protein (Rb), or amplification associated overexpression of CDK4 is observed in distinct subsets of malignant glial tumors and cell lines
    • He, J., J. J. Olson, and C. D. James. 1995. Lack of p16INK4 or retinoblastoma protein (Rb), or amplification associated overexpression of CDK4 is observed in distinct subsets of malignant glial tumors and cell lines. Cancer Res. 55:4833-4836.
    • (1995) Cancer Res. , vol.55 , pp. 4833-4836
    • He, J.1    Olson, J.J.2    James, C.D.3
  • 22
    • 0030046322 scopus 로고    scopus 로고
    • Hypermethylation associated inactivation indicates a tumor suppressor role for p15/INK4b1
    • Herman, J. G., J. Jen, A. Merlo, and S. B. Baylin. 1996. Hypermethylation associated inactivation indicates a tumor suppressor role for p15/INK4b1. Cancer Res. 56:722-727.
    • (1996) Cancer Res. , vol.56 , pp. 722-727
    • Herman, J.G.1    Jen, J.2    Merlo, A.3    Baylin, S.B.4
  • 23
    • 0032568323 scopus 로고    scopus 로고
    • Regulation of the CDK inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F
    • Hiyama, H., Iavarone A., and S. A. Reeves. 1998. Regulation of the CDK inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F. Oncogene 16:1513-1523.
    • (1998) Oncogene , vol.16 , pp. 1513-1523
    • Hiyama, H.1    Iavarone, A.2    Reeves, S.A.3
  • 24
    • 0029965696 scopus 로고    scopus 로고
    • Protein kinase C isozymes and substrates
    • Jaken, S. 1996. Protein kinase C isozymes and substrates. Curr. Opin. Cell Biol. 8:168-173.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 168-173
    • Jaken, S.1
  • 25
    • 0030756473 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2
    • Jones, D. L., R. M. Alani, and K. Munger. 1997. The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2. Genes Dev. 11:2101-2111.
    • (1997) Genes Dev. , vol.11 , pp. 2101-2111
    • Jones, D.L.1    Alani, R.M.2    Munger, K.3
  • 27
    • 0027297104 scopus 로고
    • Characterization of ligand and substrate specificity for the calcium-dependent and calcium independent protein kinase C isozymes
    • Kazanietz, M. G., L. B. Areces, A. Bahador, H. Mischak, J. Goodnight, J. F. Mushinski, and P. M. Blumberg. 1993. Characterization of ligand and substrate specificity for the calcium-dependent and calcium independent protein kinase C isozymes. Mol. Pharmacol. 44:298-307.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 298-307
    • Kazanietz, M.G.1    Areces, L.B.2    Bahador, A.3    Mischak, H.4    Goodnight, J.5    Mushinski, J.F.6    Blumberg, P.M.7
  • 28
    • 0031749730 scopus 로고    scopus 로고
    • Expression of retinoblastoma gene product and p21/ Waf1/Cip1 protein in gliomas: Correlations with proliferation markers, p53 expression and survival
    • Korkolopoulou, P., K. Kouzelis, P. Christodoulou, A. Papanikolaou, and E. Thomas-Tsagli. 1998. Expression of retinoblastoma gene product and p21/ Waf1/Cip1 protein in gliomas: correlations with proliferation markers, p53 expression and survival. Acta Neuropathol. 95:617-624.
    • (1998) Acta Neuropathol. , vol.95 , pp. 617-624
    • Korkolopoulou, P.1    Kouzelis, K.2    Christodoulou, P.3    Papanikolaou, A.4    Thomas-Tsagli, E.5
  • 29
    • 0030020675 scopus 로고    scopus 로고
    • Cell cycle arrest in G2 phase induced by phorbol ester and diacylglycerol in vascular endothelial cells
    • Kosaka, C., T. Sasaguri, A. Ishida, and J. Ogata. 1996. Cell cycle arrest in G2 phase induced by phorbol ester and diacylglycerol in vascular endothelial cells. Am. J. Physiol. 270:C170-C178.
    • (1996) Am. J. Physiol. , vol.270
    • Kosaka, C.1    Sasaguri, T.2    Ishida, A.3    Ogata, J.4
  • 31
    • 0028990868 scopus 로고
    • The cdc-2 related kinase, PISSLRE, is essential for cell growth and acts in G2 phase of the cell cycle
    • Li, S., T. K. MacLachlan, A. De Luca, P. P. Claudio, G. Condorelli, and A. Giordano. 1995. The cdc-2 related kinase, PISSLRE, is essential for cell growth and acts in G2 phase of the cell cycle. Cancer Res. 55:3992-3995.
    • (1995) Cancer Res. , vol.55 , pp. 3992-3995
    • Li, S.1    MacLachlan, T.K.2    De Luca, A.3    Claudio, P.P.4    Condorelli, G.5    Giordano, A.6
  • 32
    • 0029940572 scopus 로고    scopus 로고
    • Linking protein kinase C to the cell cycle: Ectopic expression of PKC eta in N1H-3T3 cells alters the expression of cyclins and CDK inhibitors and induces adipogenesis
    • Livneh, E., T. Shimon, E. Bechor, Y. Doki, I. Schieren, and I. B. Weinstein. 1996. Linking protein kinase C to the cell cycle: ectopic expression of PKC eta in N1H-3T3 cells alters the expression of cyclins and CDK inhibitors and induces adipogenesis. Oncogene 12:1545-1555.
    • (1996) Oncogene , vol.12 , pp. 1545-1555
    • Livneh, E.1    Shimon, T.2    Bechor, E.3    Doki, Y.4    Schieren, I.5    Weinstein, I.B.6
  • 33
    • 0030795939 scopus 로고    scopus 로고
    • Linking protein kinase C to cell cycle control
    • Livneh, E., and D. D. Fishman. 1997. Linking protein kinase C to cell cycle control. Eur. J. Biochem. 248:1-9.
    • (1997) Eur. J. Biochem. , vol.248 , pp. 1-9
    • Livneh, E.1    Fishman, D.D.2
  • 35
    • 0031011719 scopus 로고    scopus 로고
    • Differential control of cyclins D1 and D3 and the CDK inhibitor p27/Kip1 by diverse signaling pathways in Swiss 3T3 cells
    • Mann, D. J., T. Higgins, N. C. Jones, and E. Rozengurt. 1997. Differential control of cyclins D1 and D3 and the CDK inhibitor p27/Kip1 by diverse signaling pathways in Swiss 3T3 cells. Oncogene 14:1759-1766.
    • (1997) Oncogene , vol.14 , pp. 1759-1766
    • Mann, D.J.1    Higgins, T.2    Jones, N.C.3    Rozengurt, E.4
  • 36
    • 0029661875 scopus 로고    scopus 로고
    • Involvement of p21Cip1 and p27Kip1 in the molecular mechanisms of steel factor induced proliferative synergy in vitro and of p21Cip1 in the maintenance of stem/progenitor cells in vivo
    • Mantel, C., Z. Luo, J. Canfield, S. Braun, C. Deng, and H. E. Broxmeyer. 1996. Involvement of p21Cip1 and p27Kip1 in the molecular mechanisms of Steel Factor induced proliferative synergy in vitro and of p21Cip1 in the maintenance of stem/progenitor cells in vivo. Blood 88:3710-3719.
    • (1996) Blood , vol.88 , pp. 3710-3719
    • Mantel, C.1    Luo, Z.2    Canfield, J.3    Braun, S.4    Deng, C.5    Broxmeyer, H.E.6
  • 39
    • 0032104245 scopus 로고    scopus 로고
    • The extended protein kinase C super-family
    • Mellor, H. and P. J. Parker. 1998. The extended protein kinase C super-family. Biochem. J. 332:281-292.
    • (1998) Biochem. J. , vol.332 , pp. 281-292
    • Mellor, H.1    Parker, P.J.2
  • 41
    • 0030987070 scopus 로고    scopus 로고
    • Regulation of protein kinase C
    • Newton, A. C. 1997. Regulation of protein kinase C. Curr. Opin. Cell Biol. 9: 161-167.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 161-167
    • Newton, A.C.1
  • 43
    • 0031040640 scopus 로고    scopus 로고
    • The effect of Calphostin C, a potent photodependent protein kinase C inhibitor, on the proliferation of glioma cells in vitro
    • Pollack, I. F., and S. Kawecki. 1997. The effect of Calphostin C, a potent photodependent protein kinase C inhibitor, on the proliferation of glioma cells in vitro. J. Neurooncol. 31:255-266.
    • (1997) J. Neurooncol. , vol.31 , pp. 255-266
    • Pollack, I.F.1    Kawecki, S.2
  • 44
    • 0025733712 scopus 로고
    • Activation of the PKC isotypes alpha, beta 1, gamma, delta, and epsilon by phorbol esters of different biological activities
    • Ryves, W. J., A. T. Evans, A. R. Olivier, P. J. Parker, and F. J. Evans. 1991. Activation of the PKC isotypes alpha, beta 1, gamma, delta, and epsilon by phorbol esters of different biological activities. FEBS Lett. 288:5-9.
    • (1991) FEBS Lett. , vol.288 , pp. 5-9
    • Ryves, W.J.1    Evans, A.T.2    Olivier, A.R.3    Parker, P.J.4    Evans, F.J.5
  • 45
    • 0031864708 scopus 로고    scopus 로고
    • A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth
    • Sioud, M. and D. R. Sorensen. 1998. A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth. Nat. Biotechnol. 16:556-561.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 556-561
    • Sioud, M.1    Sorensen, D.R.2
  • 46
    • 0028879890 scopus 로고
    • Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma
    • Sonoda, Y., T. Yoshimoto, and T. Sekiya. 1995. Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma. Oncogene 11:2145-2149.
    • (1995) Oncogene , vol.11 , pp. 2145-2149
    • Sonoda, Y.1    Yoshimoto, T.2    Sekiya, T.3
  • 47
    • 0030002649 scopus 로고    scopus 로고
    • Deletions and rearrangements inactivate the p16/INK4 gene in human glioma cells
    • Srivenugopal, K. S., and F. Ali-Osman. 1996. Deletions and rearrangements inactivate the p16/INK4 gene in human glioma cells. Oncogene 12:2029-2034.
    • (1996) Oncogene , vol.12 , pp. 2029-2034
    • Srivenugopal, K.S.1    Ali-Osman, F.2
  • 48
    • 0029666264 scopus 로고    scopus 로고
    • Beta2 protein kinase C is required for the G2/M transition of cell cycle
    • Thompson, L. J., and A. P. Fields. 1996. Beta2 protein kinase C is required for the G2/M transition of cell cycle. J. Biol. Chem. 271:15045-15053.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15045-15053
    • Thompson, L.J.1    Fields, A.P.2
  • 49
    • 0029833019 scopus 로고    scopus 로고
    • Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide
    • Yazaki, T., S. Ahmad, A. Chablavi, E. Zylber-Katz, N. M. Dean, S. D. Rabkin, R. L. Martuza, and R. I. Glazer. 1996. Treatment of glioblastoma U-87 by systemic administration of an antisense protein kinase C-alpha phosphorothioate oligodeoxynucleotide. Mol. Pharmacol. 50:236-242.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 236-242
    • Yazaki, T.1    Ahmad, S.2    Chablavi, A.3    Zylber-Katz, E.4    Dean, N.M.5    Rabkin, S.D.6    Martuza, R.L.7    Glazer, R.I.8
  • 50
    • 0028094798 scopus 로고
    • Protein kinase C in cultured adult human oligodendrocytes: A potential role for isoform alpha as a mediator of process outgrowth
    • Yong, V. W., N. P. Dooley, and P. G. Noble. 1994. Protein kinase C in cultured adult human oligodendrocytes: a potential role for isoform alpha as a mediator of process outgrowth. J. Neurosci. Res. 39:83-96.
    • (1994) J. Neurosci. Res. , vol.39 , pp. 83-96
    • Yong, V.W.1    Dooley, N.P.2    Noble, P.G.3
  • 51
    • 0029670422 scopus 로고    scopus 로고
    • Regulation of P21/Waf1/Cip1 expression by p53 independent mechanisms
    • Zeng, Y.-X., and W. S. El-Deiry. 1996. Regulation of P21/Waf1/Cip1 expression by p53 independent mechanisms. Oncogene 12:1557-1564.
    • (1996) Oncogene , vol.12 , pp. 1557-1564
    • Zeng, Y.-X.1    El-Deiry, W.S.2
  • 52
    • 0030701842 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor p21cip1 mediates the growth inhibitory effect of phorbol esters in human venous endothelial cells
    • Zezula, J., V. Sexl, C. Hutter, A. Karel, W. Schutz, and M. Freissmuth. 1997. The cyclin-dependent kinase inhibitor p21cip1 mediates the growth inhibitory effect of phorbol esters in human venous endothelial cells. J. Biol. Chem. 272:29967-29974.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29967-29974
    • Zezula, J.1    Sexl, V.2    Hutter, C.3    Karel, A.4    Schutz, W.5    Freissmuth, M.6
  • 53
    • 0028169236 scopus 로고
    • p21-containing cyclin kinases exist in both active and inactive states
    • Zhang, H., G. H. Hannon, and D. Beach. 1994. p21-containing cyclin kinases exist in both active and inactive states. Genes Dev. 8:1750-1758.
    • (1994) Genes Dev. , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.H.2    Beach, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.