Arecoline decreases interleukin-6 production and induces apoptosis and cell cycle arrest in human basal cell carcinoma cells

Toxicology and Applied Pharmacology

Volumn 258, Issue 2, 2012, Pages 199-207

  Huang, Li Wen ^a   Hsieh, Bau Shan ^b   Cheng, Hsiao Ling ^b   Hu, Yu Chen ^b   Chang, Wen Tsan ^b,c   Chang, Kee Lung ^b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Arecoline; BCC; Interleukin 6; P53

Indexed keywords

ARECOLINE; CASPASE 3; CYCLIN DEPENDENT KINASE 1; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BCL 2; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BASAL CELL CARCINOMA; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL STRUCTURE; CELL VIABILITY; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KERATINOCYTE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; ARECOLINE; CARCINOMA, BASAL CELL; CASPASE 3; CELL CYCLE; CELL LINE; CHROMATIN; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-6; KERATINOCYTES; MALE; MICE; RNA, MESSENGER; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

ARECA; MUS;

EID: 84855780139     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.11.001     Document Type: Article

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