Sustained adenosine exposure causes lung endothelial apoptosis: A possible contributor to cigarette smoke-induced endothelial apoptosis and lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 5, 2013, Pages

  Lu, Qing ^a   Sakhatskyy, Pavlo ^a   Newton, Julie ^a   Shamirian, Paul ^a   Hsiao, Vivian ^a   Curren, Sean ^a   Gabino Miranda, Gustavo Andres ^a   Pedroza, Mesias ^b   Blackburn, Michael R ^b   Rounds, Sharon ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Adenosine; Cigarette smoke; Mitochondria; Nucleoside transporters; Oxidative stress

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE RECEPTOR; CASPASE 3; CASPASE 9; CIGARETTE SMOKE; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEOSIDE TRANSPORTER; PENTOSTATIN; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENDOTHELIUM CELL; ENZYME ACTIVATION; IN VITRO STUDY; LONG TERM EXPOSURE; LUNG ALVEOLUS CELL; LUNG COMPLIANCE; LUNG EMPHYSEMA; LUNG ENDOTHELIUM; LUNG INJURY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE INHIBITORS; ANIMALS; APOPTOSIS; CATTLE; ENDOTHELIAL CELLS; ENDOTHELIUM; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG INJURY; MICE; MICE, INBRED AKR; MICE, INBRED C57BL; MITOCHONDRIA; NUCLEOSIDE TRANSPORT PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PENTOSTATIN; SMOKE;

EID: 84874636716     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00161.2012     Document Type: Article

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