Mechanism of extracellular ATP- and adenosine-induced apoptosis of cultured pulmonary artery endothelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 275, Issue 2 19-2, 1998, Pages

  Rounds, Sharon ^a,c   Yee, Winnie Lin ^b   Dawicki, Doloretta D ^a   Harrington, Elizabeth ^a   Parks, Nancy ^a   Cutaia, Michael V ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Acidosis; Adenosine 5' triphosphate; Adenosine deaminase; Adenosine kinase; Methyltransferase; Nitric oxide; S adenosyl L methionine; S adenosyl L homocysteine; S adenosyl L homocysteine hydrolase; Sodium hydrogen antiport

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE INHIBITOR; ADENOSINE TRIPHOSPHATE; ADENOSYLHOMOCYSTEINASE; ANTIPORTER; CHLOROQUINE; DNA FRAGMENT; LIPOPOLYSACCHARIDE; METHYLTRANSFERASE; NITRIC OXIDE; S ADENOSYLMETHIONINE; THYMIDINE; TUMOR NECROSIS FACTOR;

ANGIOGENESIS; ANIMAL TISSUE; APOPTOSIS; ARTERY ENDOTHELIUM; ARTICLE; CELL METABOLISM; CELL PH; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME INHIBITION; HYDROLYSIS; LUNG ARTERY; LUNG INJURY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE;

EID: 0031871194     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.275.2.l379     Document Type: Article

References (32)

1. Barry, M. A., and A. Eastman. Identification of deoxyribonuclease II as an endonuclease involved in apoptosis. Arch. Biochem. Biophys. 300: 440-450, 1993.
2. Barry, M. A., J. E. Reynolds, and A. Eastman. Etoposide-induced apoptosis in human HL-60 cells is associated with intracellular acidification. Cancer Res. 53: 2349-2357, 1993.
3. Bergmann, S., V. Shatrov, F. Ratter, S. Schiemann, K. Schulze-Osthoff, and V. Lehmann. Adenosine and homocysteine together enhance TNF-mediated cytotoxicity but do not alter activation of nuclear factor-kB in L929 cells. J. Immunol. 153: 1736-1743, 1994.
4. Chiang, P. K., R. K. Gordon, J. Tal, G. C. Zeng, B. P. Doctor, K. Pardhasaradhi, and P. P. McCann. S-adenosylmethionine and methylation. FASEB J. 10: 471-480, 1996.
5. Cui, S., J. S. Reichner, R. B. Mateo, and J. E. Albina. Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or independent mechanisms. Cancer Res. 54: 2462-2467, 1994.
6. + antiport activity in bovine pulmonary artery endothelial cells. Am. J. Physiol. 267 (Lung Cell. Mol. Physiol. 11): L649-L659, 1994.
7. Dawicki, D. D., D. Chatterjee, J. Wyche, and S. Rounds. Extracellular ATP and adenosine cause apoptosis of pulmonary artery endothelial cells. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L485-L494, 1997.
8. Dawicki, D. D., J. McGowan-Jordan, S. Bullard, S. Pond, and S. Rounds. Extracellular nucleotides stimulate leukocyte adherence to cultured pulmonary artery endothelial cells. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L666-L673, 1995.
9. De La Haba, G., and G. L. Cantoni. The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine. J. Biol. Chem. 234: 603-608, 1959.
10. 2-purinergic receptors for extracellular ATP and other nucleotides. Am. J. Physiol. 265 (Cell Physiol. 34): C577-C606, 1993.
11. Firestein, G. S., D. A. Bullough, M. D. Erion, R. Jimenez, M. Ramirez-Weinhouse, J. Barankiewicz, C. W. Smith, H. E. Gruber, and K. M. Mullane. Inhibition of neutrophil adhesion by adenosine and an adenosine kinase inhibitor. J. Immunol. 154: 326-334, 1995.
12. Gottlieb, R. A., J. Nordberg, E. Skowronski, and B. M. Babior. Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification. Proc. Natl. Acad. Sci. USA 93: 654-658, 1996.
13. Han, Z., and J. H. Wyche. Guanosine induces necrosis of cultured aortic endothelial cells. Am. J. Pathol. 145: 423-427, 1994.
14. Hoyt, D. G., R. J. Mannix, J. M. Rusnak, B. R. Pitt, and J. S. Lazo. Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells. Am. J. Physiol. 269 (Lung Cell. Mol. Physiol. 13): L171-L177, 1995.
15. Kroemer, G., P. Petit, N. Zamzami, J.-L. Vayssière, and B. Mignotte. The biochemistry of programmed cell death. FASEB J. 9: 1277-1287, 1995.
16. + antiport. J. Biol. Chem. 270: 3203-3211, 1995.
17. Li, J.-M., R. A. Fenton, B. S. Cutler, and J. G. Dobson. Adenosine enhances nitric oxide production by vascular endothelial cells. Am. J. Physiol 269 (Cell Physiol. 38): C519-C523, 1995.
18. Mehdi, S., E. T. Jarvi, J. R. Koehl, J. R. McCarthy, and P. Bey. The mechanism of inhibition of S-adenosyl-L-homocysteine hydrolase by fluorine-containing adenosine analogs. J. Enzyme Inhib. 4: 1-13, 1990.
19. Perez-Sala, D., D. Collado-Escobar, and F. Mollinedo. Intracellular alkalinization suppresses lovastatin-induced apoptosis in HL-60 cells through the inactivation of a pH-dependent endonuclease. J. Biol. Chem. 270: 6235-6242, 1995.
20. Perna, A. F., D. Ingrosso, V. Zappia, P. Galletti, G. Capasso, and N. G. De Santo. Enzymatic methyl esterification of erythrocyte membrane proteins is impaired in chronic renal failure. J. Clin. Invest. 91: 2497-2503, 1993.
21. Polunovsky, V. A., B. Chen, C. Henke, D. Snover, C. Wendt, D. H. Ingbar, and P. B. Bitterman. Role of mesenchymal cell death in lung remodeling after injury. J. Clin. Invest. 92: 388-397, 1993.
22. Polunovsky, V. A., C. H. Wendt, D. H. Ingbar, M. S. Peterson, and P. B. Bitterman. Induction of endothelial cell apoptosis by TNFα: modulation by inhibitors of protein synthesis. Exp. Cell Res. 214: 584-594, 1994.
23. Rounds, S., L. Hsieh, and K. C. Agarwal. Effects of endotoxin injury on endothelial cell adenosine metabolism. J. Lab. Clin. Med. 123: 309-317, 1994.
24. Ryan, U. S., E. Clements, D. Halliston, and J. W. Ryan. Isolation and culture of pulmonary artery endothelial cells. Tissue Cell 10: 535-554, 1978.
25. Steller, H. Mechanisms and genes of cellular suicide. Science 267: 1445-1449, 1995.
26. Starkebaum, G., and J. M. Harlan. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J. Clin. Invest. 77: 1370-1376, 1986.
27. Thompson, C. B. Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462, 1995.
28. Ueland, P. M. Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase. Pharmacol. Rev. 34: 223-253, 1982.
29. Wakade, T. D., K. C. Palmer, R. McCauley, D. A. Przywara, and A. R. Wakade. Adenosine-induced apoptosis in chick embryonic sympathetic neurons: a new physiological role for adenosine. J. Physiol. (Lond.) 488: 123-138, 1995.
30. Zanovello, P., V. Bronte, A. Rosato, P. Pizzo, and F. DiVirgilio. Responses of mouse lymphocytes to extracellular ATP. II. Extracellular ATP causes cell type-dependent lysis and DNA fragmentation. J. Immunol. 145: 1545-1550, 1990.
31. Zheng, L. M., A. Zychlinsky, C.-C. Liu, D. M. Ojcius, and J. D.-E. Young. Extracellular ATP as a trigger for apoptosis or programmed cell death. J. Cell Biol. 112: 279-288, 1991.
32. + antiport and intracellular pH in the regulation of HL-60 apoptosis. Biochim. Biophys. Acta 1269: 122-128, 1995.