Conformational signals in the C-terminal domain of methionine adenosyltransferase I/III determine its nucleocytoplasmic distribution

FASEB Journal

Volumn 23, Issue 10, 2009, Pages 3347-3360

  Reytor, Edel ^a   Pérez Miguelsanz, Juliana ^b   Alvarez, Luis ^c   Pérez Sala, Dolores ^d   Pajares, María A ^a  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^d CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Epigenetic modifications; Nuclear methylation; S adenosylmethionine synthetase; Structural determinants of localization; Tissular expression

Indexed keywords

METHIONINE ADENOSYLTRANSFERASE; METHIONINE ADENOSYLTRANSFERASE I; METHIONINE ADENOSYLTRANSFERASE III; MONOMER; S ADENOSYLMETHIONINE; TETRAMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CELL LINE; CELL NUCLEUS; CELL NUCLEUS MATRIX; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONFORMATIONAL TRANSITION; CYTOPLASM; DNA MODIFICATION; EPIGENETICS; GEL FILTRATION CHROMATOGRAPHY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIVER; METHYLATION; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS;

ANIMALS; CELL NUCLEUS; CYTOPLASM; MALE; METHIONINE ADENOSYLTRANSFERASE; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

MAMMALIA; RATTUS;

EID: 70349663508     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-130187     Document Type: Article

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