-
1
-
-
77951107086
-
Synthetic biology: Applications come of age
-
Khalil, A. S. & Collins, J. J. Synthetic biology: applications come of age. Nat. Rev. Genet. 11, 367-379 (2010)
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 367-379
-
-
Khalil, A.S.1
Collins, J.J.2
-
2
-
-
66249088017
-
The second wave of synthetic biology: From modules to systems
-
Purnick, P. E. & Weiss, R. The second wave of synthetic biology: from modules to systems. Nat. Rev. Mol. Cell. Biol. 10, 410-422 (2009)
-
(2009)
Nat. Rev. Mol. Cell. Biol.
, vol.10
, pp. 410-422
-
-
Purnick, P.E.1
Weiss, R.2
-
3
-
-
33846950348
-
Challenges in engineering microbes for biofuels production
-
Stephanopoulos, G. Challenges in engineering microbes for biofuels production. Science 315, 801-804 (2007)
-
(2007)
Science
, vol.315
, pp. 801-804
-
-
Stephanopoulos, G.1
-
4
-
-
33645870422
-
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
-
Ro, D. K. et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 440, 940-943 (2006)
-
(2006)
Nature
, vol.440
, pp. 940-943
-
-
Ro, D.K.1
-
5
-
-
17844374314
-
A synthetic multicellular system for programmed pattern formation
-
DOI 10.1038/nature03461
-
Basu, S., Gerchman, Y., Collins, C. H., Arnold, F. H. & Weiss, R. A synthetic multicellular system for programmed pattern formation. Nature 434, 1130-1134 (2005) (Pubitemid 40663491)
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1130-1134
-
-
Basu, S.1
Gerchman, Y.2
Collins, C.H.3
Arnold, F.H.4
Weiss, R.5
-
6
-
-
0034688173
-
A synthetic oscillatory network of transcriptional regulators
-
DOI 10.1038/35002125
-
Elowitz, M. B. & Leibler, S. A synthetic oscillatory network of transcriptional regulators. Nature 403, 335-338 (2000) (Pubitemid 30062393)
-
(2000)
Nature
, vol.403
, Issue.6767
, pp. 335-338
-
-
Elowitz, M.B.1
Leibier, S.2
-
7
-
-
0034688174
-
Construction of a genetic toggle switch in Escherichia coli
-
DOI 10.1038/35002131
-
Gardner, T. S., Cantor, C. R. & Collins, J. J. Construction of a genetic toggle switch in Escherichia coli. Nature 403, 339-342 (2000) (Pubitemid 30062394)
-
(2000)
Nature
, vol.403
, Issue.6767
, pp. 339-342
-
-
Gardner, T.S.1
Cantor, C.R.2
Collins, J.J.3
-
8
-
-
57049159362
-
A fast, robust and tunable synthetic gene oscillator
-
DOI 10.1038/nature07389, PII NATURE07389
-
Stricker, J. et al. A fast, robust and tunable synthetic gene oscillator. Nature 456, 516-519 (2008) (Pubitemid 352759003)
-
(2008)
Nature
, vol.456
, Issue.7221
, pp. 516-519
-
-
Stricker, J.1
Cookson, S.2
Bennett, M.R.3
Mather, W.H.4
Tsimring, L.S.5
Hasty, J.6
-
9
-
-
67549145283
-
A synthetic genetic edge detection program
-
Tabor, J. J. et al. A synthetic genetic edge detection program. Cell 137, 1272-1281 (2009)
-
(2009)
Cell
, vol.137
, pp. 1272-1281
-
-
Tabor, J.J.1
-
10
-
-
54249113318
-
Higher-order cellular information processing with synthetic RNA devices
-
Win, M. N. & Smolke, C. D. Higher-order cellular information processing with synthetic RNA devices. Science 322, 456-460 (2008)
-
(2008)
Science
, vol.322
, pp. 456-460
-
-
Win, M.N.1
Smolke, C.D.2
-
11
-
-
73549083223
-
Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem
-
Song, H., Payne, S., Gray, M. & You, L. Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem. Nat. Chem. Biol. 5, 929-935 (2009)
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 929-935
-
-
Song, H.1
Payne, S.2
Gray, M.3
You, L.4
-
12
-
-
34447505900
-
A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells
-
DOI 10.1016/j.cell.2007.05.045, PII S0092867407006848
-
Deans, T. L., Cantor, C. R. & Collins, J. J. A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell 130, 363-372 (2007) (Pubitemid 47081136)
-
(2007)
Cell
, vol.130
, Issue.2
, pp. 363-372
-
-
Deans, T.L.1
Cantor, C.R.2
Collins, J.J.3
-
13
-
-
79957457314
-
De novo design and construction of an inducible gene expression system in mammalian cells
-
Karlsson, M., Weber, W. & Fussenegger, M. De novo design and construction of an inducible gene expression system in mammalian cells. Methods Enzymol. 497, 239-253 (2011)
-
(2011)
Methods Enzymol.
, vol.497
, pp. 239-253
-
-
Karlsson, M.1
Weber, W.2
Fussenegger, M.3
-
14
-
-
80051486871
-
Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template
-
Bleris, L. et al. Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template. Mol. Syst. Biol. 7, 519 (2011)
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 519
-
-
Bleris, L.1
-
15
-
-
34447310821
-
A universal RNAi-based logic evaluator that operates in mammalian cells
-
DOI 10.1038/nbt1307, PII NBT1307
-
Rinaudo, K. et al. A universal RNAi-based logic evaluator that operates in mammalian cells. Nat. Biotechnol. 25, 795-801 (2007) (Pubitemid 47052185)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.7
, pp. 795-801
-
-
Rinaudo, K.1
Bleris, L.2
Maddamsetti, R.3
Subramanian, S.4
Weiss, R.5
Benenson, Y.6
-
16
-
-
77956431677
-
Rationally designed logic integration of regulatory signals in mammalian cells
-
Leisner, M., Bleris, L., Lohmueller, J., Xie, Z. & Benenson, Y. Rationally designed logic integration of regulatory signals in mammalian cells. Nat. Nanotechnol. 5, 666-670 (2010)
-
(2010)
Nat. Nanotechnol.
, vol.5
, pp. 666-670
-
-
Leisner, M.1
Bleris, L.2
Lohmueller, J.3
Xie, Z.4
Benenson, Y.5
-
17
-
-
84863644753
-
Synthetic memory circuits for tracking human cell fate
-
Burrill, D. R., Inniss, M. C., Boyle, P. M. & Silver, P. A. Synthetic memory circuits for tracking human cell fate. Genes Dev. 26, 1486-1497 (2012)
-
(2012)
Genes Dev.
, vol.26
, pp. 1486-1497
-
-
Burrill, D.R.1
Inniss, M.C.2
Boyle, P.M.3
Silver, P.A.4
-
18
-
-
3042822415
-
An engineered epigenetic transgene switch in mammalian cells
-
DOI 10.1038/nbt980
-
Kramer, B. P. et al. An engineered epigenetic transgene switch in mammalian cells. Nat. Biotechnol. 22, 867-870 (2004) (Pubitemid 38886606)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.7
, pp. 867-870
-
-
Kramer, B.P.1
Viretta, A.U.2
Baba, M.D.-E.3
Aubel, D.4
Weber, W.5
Fussenegger, M.6
-
19
-
-
58249117722
-
A tunable synthetic mammalian oscillator
-
Tigges, M., Marquez-Lago, T. T., Stelling, J. & Fussenegger, M. A tunable synthetic mammalian oscillator. Nature 457, 309-312 (2009)
-
(2009)
Nature
, vol.457
, pp. 309-312
-
-
Tigges, M.1
Marquez-Lago, T.T.2
Stelling, J.3
Fussenegger, M.4
-
20
-
-
78649429678
-
Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins
-
Culler, S. J., Hoff, K. G. & Smolke, C. D. Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins. Science 330, 1251-1255 (2010)
-
(2010)
Science
, vol.330
, pp. 1251-1255
-
-
Culler, S.J.1
Hoff, K.G.2
Smolke, C.D.3
-
21
-
-
80052456127
-
Multi-input RNAi-based logic circuit for identification of specific cancer cells
-
Xie, Z., Wroblewska, L., Prochazka, L., Weiss, R. & Benenson, Y. Multi-input RNAi-based logic circuit for identification of specific cancer cells. Science 333, 1307-1311 (2011)
-
(2011)
Science
, vol.333
, pp. 1307-1311
-
-
Xie, Z.1
Wroblewska, L.2
Prochazka, L.3
Weiss, R.4
Benenson, Y.5
-
22
-
-
80052484996
-
Synthetic biology moving into the clinic
-
Ruder, W. C., Lu, T. & Collins, J. J. Synthetic biology moving into the clinic. Science 333, 1248-1252 (2011)
-
(2011)
Science
, vol.333
, pp. 1248-1252
-
-
Ruder, W.C.1
Lu, T.2
Collins, J.J.3
-
23
-
-
0034608802
-
Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity
-
DOI 10.1073/pnas.130192197
-
Urlinger, S. et al. Exploring the sequence space for tetracycline- dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc. Natl Acad. Sci. USA 97, 7963-7968 (2000) (Pubitemid 30460756)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.14
, pp. 7963-7968
-
-
Urlinger, S.1
Baron, U.2
Thellmann, M.3
Hasan, M.T.4
Bujard, H.5
Hillen, W.6
-
24
-
-
0036714926
-
Macrolide-based transgene control in mammalian cells and mice
-
DOI 10.1038/nbt731
-
Weber, W. et al. Macrolide-based transgene control in mammalian cells and mice. Nat. Biotechnol. 20, 901-907 (2002) (Pubitemid 35001127)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.9
, pp. 901-907
-
-
Weber, W.1
Fux, C.2
Daoud-El Baba, M.3
Keller, B.4
Weber, C.C.5
Kramer, B.P.6
Heinzen, C.7
Aubel, D.8
Bailey, J.E.9
Fussenegger, M.10
-
25
-
-
0035491607
-
Conditional control of gene expression in the mouse
-
DOI 10.1038/35093537
-
Lewandoski, M. Conditional control of gene expression in the mouse. Nat. Rev. Genet. 2, 743-755 (2001) (Pubitemid 33685572)
-
(2001)
Nature Reviews Genetics
, vol.2
, Issue.10
, pp. 743-755
-
-
Lewandoski, M.1
-
26
-
-
0024024137
-
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression
-
Triezenberg, S. J., Kingsbury, R. C. & McKnight, S. L. Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. Genes Dev. 2, 718-729 (1988)
-
(1988)
Genes Dev.
, vol.2
, pp. 718-729
-
-
Triezenberg, S.J.1
Kingsbury, R.C.2
McKnight, S.L.3
-
27
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen, M. & Bujard, H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl Acad. Sci. USA 89, 5547-5551 (1992)
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
28
-
-
57849135041
-
RtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse
-
Morimoto, M. & Kopan, R. rtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse. Dev. Biol. 325, 171-178 (2009)
-
(2009)
Dev. Biol.
, vol.325
, pp. 171-178
-
-
Morimoto, M.1
Kopan, R.2
-
29
-
-
0032170171
-
Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells
-
Yao, F. et al. Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells. Hum. Gene Ther. 9, 1939-1950 (1998) (Pubitemid 28439099)
-
(1998)
Human Gene Therapy
, vol.9
, Issue.13
, pp. 1939-1950
-
-
Yao, F.1
Svensjo, T.2
Winkler, T.3
Lu, M.4
Eriksson, C.5
Eriksson, E.6
-
30
-
-
0023666091
-
The inducible lac operator-repressor system is functional in mammalian cells
-
Hu, M. C. & Davidson, N. The inducible lac operator-repressor system is functional in mammalian cells. Cell 48, 555-566 (1987)
-
(1987)
Cell
, vol.48
, pp. 555-566
-
-
Hu, M.C.1
Davidson, N.2
-
31
-
-
0041930790
-
Artificial regulatory networks and cascades for discrete multilevel transgene control in mammalian cells
-
DOI 10.1002/bit.10731
-
Kramer, B. P., Weber, W. & Fussenegger, M. Artificial regulatory networks and cascades for discrete multilevel transgene control in mammalian cells. Biotechnol. Bioeng. 83, 810-820 (2003) (Pubitemid 37039602)
-
(2003)
Biotechnology and Bioengineering
, vol.83
, Issue.7
, pp. 810-820
-
-
Kramer, B.P.1
Weber, W.2
Fussenegger, M.3
-
32
-
-
41649103031
-
Turning the gene tap off; implications of regulating gene expression for cancer therapeutics
-
DOI 10.1158/1535-7163.MCT-07-2328
-
Curtin, J. F., Candolfi, M., Xiong, W., Lowenstein, P. R. & Castro, M. G. Turning the gene tap off; implications of regulating gene expression for cancer therapeutics. Mol. Cancer Ther. 7, 439-448 (2008) (Pubitemid 351482126)
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, Issue.3
, pp. 439-448
-
-
Curtin, J.F.1
Candolfi, M.2
Xiong, W.3
Lowenstein, P.R.4
Castro, M.G.5
-
33
-
-
50549093286
-
Gene transfer: The challenge of regulated gene expression
-
Guo, Z. S., Li, Q., Bartlett, D. L., Yang, J. Y. & Fang, B. Gene transfer: the challenge of regulated gene expression. Trends Mol. Med. 14, 410-418 (2008)
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 410-418
-
-
Guo, Z.S.1
Li, Q.2
Bartlett, D.L.3
Yang, J.Y.4
Fang, B.5
-
34
-
-
33748195107
-
A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules
-
DOI 10.1016/j.cell.2006.07.025, PII S0092867406010130
-
Banaszynski, L. A., Chen, L. C., Maynard-Smith, L. A., Ooi, A. G. & Wandless, T. J. A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules. Cell 126, 995-1004 (2006) (Pubitemid 44310772)
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 995-1004
-
-
Banaszynski, L.A.1
Chen, L.-c.2
Maynard-Smith, L.A.3
Ooi, A.G.L.4
Wandless, T.J.5
-
35
-
-
62549083590
-
Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression
-
Nevozhay, D., Adams, R. M., Murphy, K. F., Josic, K. & Balázsi, G. Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression. Proc. Natl Acad. Sci. USA 106, 5123-5128 (2009)
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 5123-5128
-
-
Nevozhay, D.1
Adams, R.M.2
Murphy, K.F.3
Josic, K.4
Balázsi, G.5
-
36
-
-
33845616177
-
Phenotypic consequences of promoter-mediated transcriptional noise
-
DOI 10.1016/j.molcel.2006.11.003, PII S1097276506007441
-
Blake, W. J. et al. Phenotypic consequences of promoter-mediated transcriptional noise. Mol. Cell 24, 853-865 (2006) (Pubitemid 44960090)
-
(2006)
Molecular Cell
, vol.24
, Issue.6
, pp. 853-865
-
-
Blake, W.J.1
Balazsi, G.2
Kohanski, M.A.3
Isaacs, F.J.4
Murphy, K.F.5
Kuang, Y.6
Cantor, C.R.7
Walt, D.R.8
Collins, J.J.9
-
37
-
-
0022371467
-
A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
-
Boshart, M. et al. A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 41, 521-530 (1985) (Pubitemid 16219422)
-
(1985)
Cell
, vol.41
, Issue.2
, pp. 521-530
-
-
Boshart, M.1
Weber, F.2
Jahn, G.3
-
38
-
-
0015762456
-
A human cell line from a pleural effusion derived from a breast carcinoma
-
Soule, H. D., Vazguez, J., Long, A., Albert, S. & Brennan, M. A human cell line from a pleural effusion derived from a breast carcinoma. J. Natl Cancer Inst. 51, 1409-1416 (1973)
-
(1973)
J. Natl Cancer Inst.
, vol.51
, pp. 1409-1416
-
-
Soule, H.D.1
Vazguez, J.2
Long, A.3
Albert, S.4
Brennan, M.5
-
39
-
-
0027501690
-
Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements
-
DOI 10.1016/0968-0004(93)90009-C
-
Gossen, M., Bonin, A. L. & Bujard, H. Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements. Trends Biochem. Sci. 18, 471-475 (1993) (Pubitemid 23362304)
-
(1993)
Trends in Biochemical Sciences
, vol.18
, Issue.12
, pp. 471-475
-
-
Gossen, M.1
Bonin, A.L.2
Bujard, H.3
-
40
-
-
34447536422
-
A more efficient RNAi inducible system for tight regulation of gene expression in mammalian cells and xenograft animals
-
DOI 10.1261/rna.520707
-
Zhang, J. et al. A more efficient RNAi inducible system for tight regulation of gene expression in mammalian cells and xenograft animals. RNA 13, 1375-1383 (2007) (Pubitemid 47080481)
-
(2007)
RNA
, vol.13
, Issue.8
, pp. 1375-1383
-
-
Zhang, J.1
Wang, C.2
Ke, N.3
Bliesath, J.4
Chionis, J.5
He, Q.S.6
Li, Q.-X.7
Chatterton, J.E.8
Wong-Staal, F.9
Zhou, D.10
-
41
-
-
77952492425
-
Tuning and controlling gene expression noise in synthetic gene networks
-
Murphy, K. F., Adams, R. M., Wang, X., Balázsi, G. & Collins, J. J. Tuning and controlling gene expression noise in synthetic gene networks. Nucleic Acids Res. 38, 2712-2726 (2010)
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 2712-2726
-
-
Murphy, K.F.1
Adams, R.M.2
Wang, X.3
Balázsi, G.4
Collins, J.J.5
-
42
-
-
0038780670
-
Eukaryotic intron loss
-
DOI 10.1126/science.1080559
-
Mourier, T. & Jeffares, D. C. Eukaryotic intron loss. Science 300, 1393 (2003) (Pubitemid 36638151)
-
(2003)
Science
, vol.300
, Issue.5624
, pp. 1393
-
-
Mourier, T.1
Jeffares, D.C.2
-
43
-
-
0001372225
-
Introns increase transcriptional efficiency in transgenic mice
-
Brinster, R. L., Allen, J. M., Behringer, R. R., Gelinas, R. E. & Palmiter, R. D. Introns increase transcriptional efficiency in transgenic mice. Proc. Natl Acad. Sci. USA 85, 836-840 (1988) (Pubitemid 18073924)
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, Issue.3
, pp. 836-840
-
-
Brinster, R.L.1
Allen, J.M.2
Behringer, R.R.3
Gelinas, R.E.4
Palmiter, R.D.5
-
44
-
-
0025906388
-
A generic intron increases gene expression in transgenic mice
-
Choi, T., Huang, M., Gorman, C. & Jaenisch, R. A generic intron increases gene expression in transgenic mice. Mol. Cell. Biol. 11, 3070-3074 (1991) (Pubitemid 21895693)
-
(1991)
Molecular and Cellular Biology
, vol.11
, Issue.6
, pp. 3070-3074
-
-
Choi, T.1
Huang, M.2
Gorman, C.3
Jaenisch, R.4
-
45
-
-
51149120433
-
Intron-mediated regulation of gene expression
-
Rose, A. B. Intron-mediated regulation of gene expression. Curr. Top Microbiol. Immunol. 326, 277-290 (2008)
-
(2008)
Curr. Top Microbiol. Immunol.
, vol.326
, pp. 277-290
-
-
Rose, A.B.1
-
46
-
-
0025269031
-
Intervening sequences increase efficiency of RNA 3' processing and accumulation of cytoplasmic RNA
-
Huang, M. T. & Gorman, C. M. Intervening sequences increase efficiency of RNA 3' processing and accumulation of cytoplasmic RNA. Nucleic Acids Res. 18, 937-947 (1990)
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 937-947
-
-
Huang, M.T.1
Gorman, C.M.2
-
47
-
-
0018688932
-
Comparison of total sequence of a cloned rabbit β-globin gene and its flanking regions with a homologous mouse sequence
-
van Ooyen, A., van den Berg, J., Mantei, N. & Weissmann, C. Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence. Science 206, 337-344 (1979) (Pubitemid 10244190)
-
(1979)
Science
, vol.206
, Issue.4416
, pp. 337-344
-
-
Van Ooyen, A.1
Van Den Berg, J.2
Mantei, N.3
Weissmann, C.4
-
48
-
-
0033516966
-
Codon optimization effect on translational efficiency of DNA vaccine in mammalian cells: Analysis of plasmid DNA encoding a CTL epitope derived from microorganisms
-
DOI 10.1006/bbrc.1999.1050
-
Nagata, T., Uchijima, M., Yoshida, A., Kawashima, M. & Koide, Y. Codon optimization effect on translational efficiency of DNA vaccine in mammalian cells: analysis of plasmid DNA encoding a CTL epitope derived from microorganisms. Biochem. Biophys. Res. Commun. 261, 445-451 (1999) (Pubitemid 29392495)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.261
, Issue.2
, pp. 445-451
-
-
Nagata, T.1
Uchijima, M.2
Yoshida, A.3
Kawashima, M.4
Koide, Y.5
-
49
-
-
0029909407
-
Optimized codon usage and chromophore mutations provide enhanced sensitivity with the green fluorescent protein
-
DOI 10.1093/nar/24.22.4592
-
Yang, T. T., Cheng, L. & Kain, S. R. Optimized codon usage and chromophore mutations provide enhanced sensitivity with the green fluorescent protein. Nucleic Acids Res. 24, 4592-4593 (1996) (Pubitemid 26388650)
-
(1996)
Nucleic Acids Research
, vol.24
, Issue.22
, pp. 4592-4593
-
-
Yang, T.-T.1
Cheng, L.2
Kain, S.R.3
-
50
-
-
0021716406
-
A short amino acid sequence able to specify nuclear location
-
Kalderon, D., Roberts, B. L., Richardson, W. D. & Smith, A. E. A short amino acid sequence able to specify nuclear location. Cell 39, 499-509 (1984) (Pubitemid 15198589)
-
(1984)
Cell
, vol.39
, Issue.3
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
51
-
-
33645103149
-
Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression
-
Schambach, A. et al. Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression. Gene Ther. 13, 641-645 (2006)
-
(2006)
Gene Ther.
, vol.13
, pp. 641-645
-
-
Schambach, A.1
-
52
-
-
0023665902
-
An analysis of 50-noncoding sequences from 699 vertebrate messenger RNAs
-
Kozak, M. An analysis of 50-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15, 8125-8148 (1987)
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 8125-8148
-
-
Kozak, M.1
-
53
-
-
33750345805
-
Rational design of a super core promoter that enhances gene expression
-
DOI 10.1038/nmeth937, PII NMETH937
-
Juven-Gershon, T., Cheng, S. & Kadonaga, J. T. Rational design of a super core promoter that enhances gene expression. Nat. Methods 3, 917-922 (2006) (Pubitemid 44614727)
-
(2006)
Nature Methods
, vol.3
, Issue.11
, pp. 917-922
-
-
Juven-Gershon, T.1
Cheng, S.2
Kadonaga, J.T.3
-
54
-
-
34547925618
-
Combinatorial promoter design for engineering noisy gene expression
-
DOI 10.1073/pnas.0608451104
-
Murphy, K. F., Balázsi, G. & Collins, J. J. Combinatorial promoter design for engineering noisy gene expression. Proc. Natl Acad. Sci. USA 104, 12726-12731 (2007) (Pubitemid 47255222)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.31
, pp. 12726-12731
-
-
Murphy, K.F.1
Balazsi, G.2
Collins, J.J.3
-
55
-
-
24644516989
-
Optimization of tetracycline-responsive recombinant protein production and effect on cell growth and ER stress in mammalian cells
-
DOI 10.1002/bit.20566
-
Jones, J. et al. Optimization of tetracycline-responsive recombinant protein production and effect on cell growth and ER stress in mammalian cells. Biotechnol. Bioeng. 91, 722-732 (2005) (Pubitemid 41283865)
-
(2005)
Biotechnology and Bioengineering
, vol.91
, Issue.6
, pp. 722-732
-
-
Jones, J.1
Nivitchanyong, T.2
Giblin, C.3
Ciccarone, V.4
Judd, D.5
Gorfien, S.6
Krag, S.S.7
Betenbaugh, M.J.8
-
56
-
-
57849135041
-
RtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse
-
Morimoto, M. & Kopan, R. rtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse. Dev. Biol. 325, 171-178 (2009)
-
(2009)
Dev. Biol.
, vol.325
, pp. 171-178
-
-
Morimoto, M.1
Kopan, R.2
-
57
-
-
0026463972
-
Transgenic mice with a rhodopsin mutation (Pro23His): A mouse model of autosomal dominant retinitis pigmentosa
-
Olsson, J. E. et al. Transgenic mice with a rhodopsin mutation (Pro23His): a mouse model of autosomal dominant retinitis pigmentosa. Neuron 9, 815-830 (1992)
-
(1992)
Neuron
, vol.9
, pp. 815-830
-
-
Olsson, J.E.1
-
58
-
-
46949091517
-
Refinement and standardization of synthetic biological parts and devices
-
DOI 10.1038/nbt1413, PII NBT1413
-
Canton, B., Labno, A. & Endy, D. Refinement and standardization of synthetic biological parts and devices. Nat. Biotechnol. 26, 787-793 (2008) (Pubitemid 351961452)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.7
, pp. 787-793
-
-
Canton, B.1
Labno, A.2
Endy, D.3
-
59
-
-
65949097067
-
FlowCore: A bioconductor package for high throughput flow cytometry
-
Hahne, F. et al. flowCore: a bioconductor package for high throughput flow cytometry. BMC Bioinform. 10, 106 (2009)
-
(2009)
BMC Bioinform.
, vol.10
, pp. 106
-
-
Hahne, F.1
-
60
-
-
17644372713
-
Dizzy: Stochastic simulation of large-scale genetic regulatory networks (supplementary material)
-
DOI 10.1142/S0219720005001144, PII S0219720005001144
-
Ramsey, S., Orrell, D. & Bolouri, H. Dizzy: stochastic simulation of large-scale genetic regulatory networks (supplementary material). J. Bioinform. Comput. Biol. 3, 437-454 (2005). (Pubitemid 40561396)
-
(2005)
Journal of Bioinformatics and Computational Biology
, vol.3
, Issue.2
, pp. 437-454
-
-
Ramsey, S.1
Orrell, D.2
Bolouri, H.3
|