Artificial regulatory networks and cascades for discrete multilevel transgene control in mammalian cells

Biotechnology and Bioengineering

Volumn 83, Issue 7, 2003, Pages 810-820

  Kramer, Beat P ^a   Weber, Wilfried ^a   Fussenegger, Martin ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Autoregulation; Gene networks; Heterologous gene regulation; Macrolide responsive gene expression system (E.REX system); Streptogramin responsive gene expression system (PIP system); Tetracycline responsive gene expression system (Tet system)

Indexed keywords

ANIMAL CELL CULTURE; ANTIBIOTICS; TISSUE CULTURE;

GENE TRANSCRIPTIONS;

GENETIC ENGINEERING;

ALKALINE PHOSPHATASE PLACENTA ISOENZYME; AMYLASE; ANTIBIOTIC AGENT; ERYTHROMYCIN; MACROLIDE; MESSENGER RNA; PRISTINAMYCIN; STREPTOGRAMIN; TETRACYCLINE;

ANIMAL CELL; ARTICLE; ARTIFICIAL REGULATORY NETWORK; CHEMOLUMINESCENCE; CHO CELL; COLORIMETRY; CONTROL SYSTEM; GENE EXPRESSION REGULATION; GENE NETWORK; GENE THERAPY; MAMMAL CELL; MOLECULAR CLONING; NONHUMAN; PLASMID; TISSUE SPECIFICITY; TRANSGENE;

ALKALINE PHOSPHATASE; ALPHA-AMYLASE; ANIMALS; ANTI-BACTERIAL AGENTS; BIOTECHNOLOGY; CELLS; CELLS, CULTURED; CHEMILUMINESCENT MEASUREMENTS; CHO CELLS; CRICETINAE; CRICETULUS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMANS; MACROLIDES; MAMMALS; NEURAL NETWORKS (COMPUTER); PLASMIDS; STREPTOGRAMINS; TETRACYCLINE; TRANS-ACTIVATORS; TRANSFECTION; TRANSGENES;

MAMMALIA; SIGMOIDEA;

EID: 0041930790     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10731     Document Type: Article

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