Biselectivity of isoDGR peptides for fibronectin binding integrin subtypes α5β1 and αvβ6: Conformational control through flanking amino acids

Journal of Medicinal Chemistry

Volumn 56, Issue 4, 2013, Pages 1509-1519

  Bochen, Alexander ^a   Marelli, Udaya Kiran ^a   Otto, Elke ^a   Pallarola, Diego ^b,f   Mas Moruno, Carlos ^a   Di Leva, Francesco Saverio ^c   Boehm, Heike ^b,f   Spatz, Joachim P ^b,f   Novellino, Ettore ^d   Kessler, Horst ^a,e   Marinelli, Luciana ^d  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b MAX PLANCK INSTITUTE FOR INTELLIGENT SYSTEMS   (Germany)

^c ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAVBETA6 INTEGRIN; FIBRONECTIN BINDING PROTEIN; MACROGOL; PENTAPEPTIDE; PHENYLGLYCINE; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL ADHESION; CHEMICAL BOND; CHIRALITY; CONFORMATIONAL TRANSITION; CYCLIZATION; DYNAMICS; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; GEOMETRY; IC 50; MOLECULAR DOCKING; MOLECULAR IMAGING; NONHUMAN; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RAT; STEREOCHEMISTRY;

EID: 84874612648     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301221x     Document Type: Article

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