Stereoisomerism and biological activity of the selective and superactive α(v)β3 integrin inhibitor cyclo(-RGDfV-) and its retro-inverso peptide

Journal of the American Chemical Society

Volumn 119, Issue 6, 1997, Pages 1328-1335

  Wermuth, J ^a   Goodman, S L ^b   Jonczyk, A ^b   Kessler, H ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b MERCK KGAA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLO(ARGINYLGLYCYLASPARTYL DEXTRO PHENYLALANYLVALINE); CYCLOPENTAPEPTIDE; CYCLOPEPTIDE; CYTOTOXIC AGENT; FIBRINOGEN; INTEGRIN; UNCLASSIFIED DRUG; VITRONECTIN;

ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE; PEPTIDE SYNTHESIS; PROTEIN BINDING; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

EID: 0030901692     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja961908l     Document Type: Article

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