Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching

Journal of Biological Chemistry

Volumn 285, Issue 12, 2010, Pages 9114-9123

  Curnis, Flavio ^a   Cattaneo, Angela ^a   Longhi, Renato ^b   Sacchi, Angelina ^a   Gasparri, Anna Maria ^a   Pastorino, Fabio ^c   Di Matteo, Paola ^d   Traversari, Catia ^d   Bachi, Angela ^a   Ponzoni, Mirco ^c   Rizzardi, Gian Paolo ^d   Corti, Angelo ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b CNR   (Italy)

^c G GASLINI INSTITUTE   (Italy)

^d MOLMED S P A   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO GROUP; ANTICANCER DRUG; BIOLOGICAL PROPERTIES; CYCLIC PEPTIDES; DEGRADATION REACTION; DEGRADATION STUDY; DESIGN AND DEVELOPMENT; INTEGRINS; LINEAR PEPTIDES; MOLECULAR SCAFFOLDS; NATURAL PROTEINS; NEOVASCULATURE; NON-FUNCTIONAL; PEPTIDE SCAFFOLDS; POTENTIAL FUNCTION; RING COMPOUNDS; STRUCTURE-ACTIVITY STUDIES; TARGETED DELIVERY; TUMOR GROWTH;

ACETYLATION; ADHESION; AMINO ACIDS; BLOOD VESSEL PROSTHESES; CELL ADHESION; DEGRADATION; DRUG DELIVERY; ENDOTHELIAL CELLS; GLYCOPROTEINS; SCAFFOLDS; SELF ASSEMBLY; TUMORS;

PEPTIDES;

ALPHAVBETA1 INTEGRIN; ALPHAVBETA6 INTEGRIN; ALPHAVBETA8 INTEGRIN; ASPARAGINYLGLYCYLARGININE; INTEGRIN; INTEGRIN RECEPTOR; ISOASPARTYLGLYCYLARGININE; MICROSOMAL AMINOPEPTIDASE; MOLECULAR SCAFFOLD; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; ANTINEOPLASTIC AGENT; DISULFIDE; ISOASPARTIC ACID; NGR PEPTIDE; OLIGOPEPTIDE; RECOMBINANT PROTEIN;

ACETYLATION; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL LINE; CONTROLLED STUDY; ENDOTHELIUM CELL; FIBROSARCOMA; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; SOLID TUMOR; STRUCTURE ACTIVITY RELATION; TUMOR GROWTH; TUMOR VASCULARIZATION; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; CYTOLOGY; METABOLISM;

ANIMALS; ANTIGENS, CD13; ANTINEOPLASTIC AGENTS; CELL ADHESION; DISULFIDES; ENDOTHELIAL CELLS; HUMANS; INTEGRINS; ISOASPARTIC ACID; MICE; MICE, INBRED BALB C; OLIGOPEPTIDES; PROTEIN BINDING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77950572672     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.044297     Document Type: Article

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