Cytotoxic Activity and Apoptosis-Inducing Potential of Di-spiropyrrolidino and Di-spiropyrrolizidino Oxindole Andrographolide Derivatives

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Dey, Sumit Kumar ^a   Bose, Dipayan ^a   Hazra, Abhijit ^a   Naskar, Subhendu ^a   Nandy, Abhishek ^a   Munda, Rudra Narayan ^a   Das, Subhadip ^a   Chatterjee, Nabanita ^a   Mondal, Nirup Bikash ^a   Banerjee, Sukdeb ^a   da Saha, Krishnas ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGRAPHOLIDE; AZOMETHINE YLIDE; CASPASE 3; CASPASE 9; DISPIROPYRROLIDINOOXINDOLE DERIVATIVE; DISPIROPYRROLIZIDINOOXINDOLE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROLINE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SARCOSINE; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DITERPENE; INDOLE DERIVATIVE; OXINDOLE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER MORTALITY; CELL CYCLE ARREST; CELL NUCLEUS; COLORECTAL CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYCLOADDITION; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LUNG CARCINOMA; MELANOMA; MITOCHONDRION; PANCREAS CARCINOMA; PROTEIN LOCALIZATION; UPREGULATION; UTERINE CERVIX CARCINOMA; CELL CYCLE; CELL CYCLE G1 PHASE; CELL SURVIVAL; CHEMICAL MODEL; CHEMISTRY; DNA DAMAGE; DRUG DESIGN; DRUG SCREENING; MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; DITERPENES; DNA DAMAGE; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; G1 PHASE; HUMANS; INDOLES; MASS SPECTROMETRY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MODELS, CHEMICAL; REACTIVE OXYGEN SPECIES;

EID: 84874600657     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058055     Document Type: Article

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