Hexosamine biosynthesis impairs insulin action via a cholesterolgenic response

Molecular Endocrinology

Volumn 27, Issue 3, 2013, Pages 536-547

  Penque, Brent A ^a   Hoggatt, April M ^a   Paul Herring, B ^a   Elmendorf, Jeffrey S ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 DIAZO 5 OXONORLEUCINE; CHOLESTEROL; GLUCOSE; HEXOSAMINE; HEXOSAMINE BIOSYNTHESIS PATHWAY; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LUCIFERASE; MESSENGER RNA; MITHRAMYCIN; N ACETYLGLUCOSAMINE; O LINKED BETA N ACETYLGLUCOSAMINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ADIPOCYTE; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELL STRAIN 3T3; CHOLESTEROL BLOOD LEVEL; CHROMATIN IMMUNOPRECIPITATION; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME MODIFICATION; ENZYME SPECIFICITY; GENE PRODUCT; GLUCOSE TRANSPORT; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION INITIATION;

3T3-L1 CELLS; ANIMALS; BIOSYNTHETIC PATHWAYS; CELL NUCLEUS; CHOLESTEROL; DIAZOOXONORLEUCINE; DNA; GLUCOSE; GLYCOSYLATION; HEXOSAMINES; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYPERINSULINISM; INSULIN; INSULIN RESISTANCE; MICE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN TRANSPORT; SP1 TRANSCRIPTION FACTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTIONAL ACTIVATION;

EID: 84874537922     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2012-1213     Document Type: Article

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