Evidence coupling increased hexosamine biosynthesis pathway activity to membrane cholesterol toxicity and cortical filamentous actin derangement contributing to cellular insulin resistance

Endocrinology

Volumn 152, Issue 9, 2011, Pages 3373-3384

  Bhonagiri, Padma ^a   Pattar, Guruprasad R ^a   Habegger, Kirk M ^a   McCarthy, Alicia M ^a   Tackett, Lixuan ^a   Elmendorf, Jeffrey S ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; F ACTIN; GLUCOSAMINE; GLUCOSE; GLUCOSE TRANSPORTER 4; GLUTAMINE FRUCTOSE 6 PHOSPHATE AMINOTRANSFERASE; HEXOSAMINE; INSULIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CARBOHYDRATE SYNTHESIS; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVITY; GENE OVEREXPRESSION; GLUCOSE TRANSPORT; GLYCOSYLATION; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN RESPONSE; INSULIN SENSITIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ACTINS; ANIMALS; CELL MEMBRANE; CHOLESTEROL; CYTOSKELETON; GLUCOSE; HEXOSAMINES; INSULIN; INSULIN RESISTANCE; MICE; NITROGENOUS GROUP TRANSFERASES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; SIGNAL TRANSDUCTION;

EID: 80052466536     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1295     Document Type: Article

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