Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle

Diabetologia

Volumn 55, Issue 2, 2012, Pages 457-467

  Habegger, K M ^a   Penque, B A ^a   Sealls, W ^a   Tackett, L ^a   Bell, L N ^a   Blue, E K ^a   Gallagher, P J ^a   Sturek, M ^a   Alloosh, M A ^a   Steinberg, H O ^b   Considine, R V ^a   Elmendorf, J S ^a  

^a INDIANA UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Actin; Cholesterol; Fatty acid; GLUT4; Insulin resistance; Membrane; Palmitate; Skeletal muscle

Indexed keywords

CHOLESTEROL; F ACTIN; GLUCOSE TRANSPORTER 4; HEXOSAMINE; PALMITIC ACID;

3 HYDROXY 3 METHYL GLUTARYL COENZYME A REDUCTASE GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT DISTRIBUTION; CARBOHYDRATE SYNTHESIS; CELL MEMBRANE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE; GENE EXPRESSION; GENE FUNCTION; GLUCOSE TRANSPORT; GLYCOSYLATION; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID RAFT; LIPID STORAGE; MALE; MOUSE; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ACTINS; ADULT; ANIMALS; BIOLOGICAL TRANSPORT; BIOPSY, NEEDLE; CELL MEMBRANE; CHOLESTEROL; CYTOSKELETON; FATTY ACIDS; FEMALE; GLUCOSE; HUMANS; INSULIN; MALE; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; MIDDLE AGED; MUSCLE, SKELETAL; PALMITIC ACID; RATS;

EID: 84856715266     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2334-y     Document Type: Article

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