Regulation of the rat SREBP-1c promoter in primary rat hepatocytes

Biochemical and Biophysical Research Communications

Volumn 290, Issue 1, 2002, Pages 256-262

  Deng, Xiong ^a   Cagen, Lauren M ^a   Wilcox, Henry G ^a   Park, Edwards A ^a   Raghow, Rajendra ^a,b   Elam, Marshall B ^a,b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUCLADESINE; GAMMA LINOLENIC ACID; GENOMIC DNA; GLUCOSE; ICOSAPENTAENOIC ACID; INSULIN; ISOPROTEIN; LINOLEIC ACID; LUCIFERASE; OLEIC ACID; PALMITIC ACID; POLYUNSATURATED FATTY ACID; PROTEIN; PROTEIN NF Y; PROTEIN SRE; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DNA FLANKING REGION; EXON; GENETIC TRANSFECTION; LIVER CELL; MALE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; REPORTER GENE; TRANSCRIPTION INITIATION;

EID: 0036291460     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.6148     Document Type: Article

References (29)

1. Nutritional and hormonal regulation of mRNA levels of lipogenic enzymes in primary cultures of rat hepatocytes
2. Identification of an inverted CCAAT box motif in the fatty acid synthase gene as an essential element for the modification of transcriptional regulation by cAMP
3. Polyunsaturated fatty acid regulation of gene transcription: A molecular mechanism to improve the metabolic syndrome
4. Molecular mechanisms of insulin modulated signaling and regulation of gene transcription
5. Physiological and nutritional regulation of enzymes of triacylglycerol synthesis
6. ADD1: A novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
7. Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
8. Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells
9. Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice
10. Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozatocin-induced diabetes
11. Sterol regulatory element binding protein 1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
12. Sterol response element binding protein 1c (SREBP1c) is involved in the polyunsaturated fatty acid suppression of hepatic S14 gene transcription
13. Insulin effects on sterol regulatory element binding protein 1c (SREBP-1c) transcriptional activity in rat hepatocytes
14. Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13
15. Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene
16. Regulation of mouse sterol regulatory element binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ
17. Identification of liver X receptor as an activator of the sterol regulatory element binding protein 1c gene promoter
18. Insulin promotes the biosynthesis and secretion of apolipoprotein B-48 by dramatically altering apolipoprotein B mRNA editing
19. Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty acid synthase gene transcription
20. Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver
21. Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes
22. Two CACGTG motifs with proper spacing dictate the carbohydrate regulation of hepatic gene transcription
23. Carbohydrate regulation of hepatic gene transcription
24. Unsaturated fatty acids down-regulate SREBP isoforms 1a and 1c by two mechanisms in HEK 293 cells
25. The roles of sterol regulatory elemenmt binding proteins in the transactivation of the rat ATP citrate-lyase promoter
26. Different sterol regulatory element-binding protein isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase
27. Different sterol regulatory element-binding protein isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase
28. Different sterol regulatory element-binding protein isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase
29. Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes