Inhibition of Nodal suppresses angiogenesis and growth of human gliomas

Journal of Neuro-Oncology

Volumn 104, Issue 1, 2011, Pages 21-31

  Hueng, Dueng Yuan ^a,b   Lin, Gu Jiun ^b   Huang, Shing Hwa ^a   Liu, Li Wen ^e   Ju, Da Tong ^a   Chen, Yuan Wu ^a   Sytwu, Huey Kang ^b   Chang, Chen ^c   Huang, Shih Ming ^b   Yeh, Yi Shian ^d   Lee, Horng Mo ^e,f   Ma, Hsin I ^a,b  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^f CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

CD31; ERK1 2; HIF 1 ; Nodal; RNA interference; VEGF

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN NODAL; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER GRADING; CANCER INHIBITION; CANCER SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE REPRESSION; GENE SILENCING; GENETIC CORRELATION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIMARY TUMOR; PROTEIN DEPLETION; PROTEIN SECRETION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SURVIVAL TIME;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD31; BENZAMIDES; BRAIN NEOPLASMS; CELL LINE, TRANSFORMED; CELL PROLIFERATION; COMPUTATIONAL BIOLOGY; DIOXOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MAGNETIC RESONANCE IMAGING; MICE; NEOVASCULARIZATION, PATHOLOGIC; NODAL PROTEIN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 80052742592     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-010-0467-3     Document Type: Article

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