Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells

Journal of Biological Chemistry

Volumn 279, Issue 27, 2004, Pages 28458-28465

  Kim, Byung Chul ^a,b   Van Gelder, Howard ^a   Kim, Tae Aug ^a   Lee, Ho Jae ^a   Baik, Kim G ^a   Chun, Hyun Hye ^a   Lee, David A ^a   Choi, Kyeong Sook ^c   Kim, Seong Jin ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Kangwon National University   (South Korea)

^c Ajou University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; ENZYMES; RNA; VIRUSES;

APOPTOSIS; PHENOTYPES;

BIOCHEMISTRY;

ACTIVIN RECEPTOR; ACTIVIN RECEPTOR LIKE KINASE 7; CASPASE 3; CASPASE 9; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN SERINE THREONINE KINASE; PROTEIN SYNTHESIS INHIBITOR; SMAD2 PROTEIN; SMAD3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSCRIPTION; HEPATOMA CELL; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RAT;

ACTIVIN RECEPTORS, TYPE I; ADENOVIRIDAE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 9; CASPASES; CELL LINE; CELL LINE, TUMOR; CELL SEPARATION; CELL SURVIVAL; CYTOCHROMES C; DNA FRAGMENTATION; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; GENES, DOMINANT; GENETIC VECTORS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLASMIDS; RATS; RNA, SMALL INTERFERING; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANS-ACTIVATORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ADENOVIRIDAE; ANIMALIA; APOGON BRACHYGRAMMUS;

EID: 3142618508     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313277200     Document Type: Article

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